| Full name: BCL2 like 10 | Alias Symbol: Diva|Boo|BCL-B | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 10017 | HGNC ID: HGNC:993 | Ensembl Gene: ENSG00000137875 | OMIM ID: 606910 |
| Drug and gene relationship at DGIdb | |||
Expression of BCL2L10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCL2L10 | 10017 | 236491_at | -0.4788 | 0.6645 | |
| GSE20347 | BCL2L10 | 10017 | 221320_at | -0.1302 | 0.0817 | |
| GSE23400 | BCL2L10 | 10017 | 221320_at | -0.0616 | 0.0969 | |
| GSE26886 | BCL2L10 | 10017 | 236491_at | 0.0682 | 0.8749 | |
| GSE29001 | BCL2L10 | 10017 | 221320_at | -0.0662 | 0.6743 | |
| GSE38129 | BCL2L10 | 10017 | 221320_at | -0.1208 | 0.1407 | |
| GSE45670 | BCL2L10 | 10017 | 236491_at | 0.0905 | 0.7254 | |
| GSE53622 | BCL2L10 | 10017 | 38923 | -0.0346 | 0.8144 | |
| GSE53624 | BCL2L10 | 10017 | 38923 | -0.3051 | 0.0044 | |
| GSE63941 | BCL2L10 | 10017 | 221320_at | 0.0621 | 0.8113 | |
| GSE77861 | BCL2L10 | 10017 | 221320_at | -0.0787 | 0.5767 | |
| GSE97050 | BCL2L10 | 10017 | A_23_P163209 | 0.0711 | 0.7537 | |
| SRP007169 | BCL2L10 | 10017 | RNAseq | -1.7185 | 0.0285 | |
| SRP064894 | BCL2L10 | 10017 | RNAseq | -0.7477 | 0.0731 | |
| SRP133303 | BCL2L10 | 10017 | RNAseq | 0.2377 | 0.6666 | |
| SRP159526 | BCL2L10 | 10017 | RNAseq | -0.8208 | 0.0561 | |
| TCGA | BCL2L10 | 10017 | RNAseq | 0.4608 | 0.1867 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BCL2L10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCL2L10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCL2L10 | 10017 | 5 | 4 | 21 | |
| GSE20123 | BCL2L10 | 10017 | 5 | 4 | 21 | |
| GSE43470 | BCL2L10 | 10017 | 4 | 3 | 36 | |
| GSE46452 | BCL2L10 | 10017 | 3 | 7 | 49 | |
| GSE47630 | BCL2L10 | 10017 | 8 | 10 | 22 | |
| GSE54993 | BCL2L10 | 10017 | 5 | 6 | 59 | |
| GSE54994 | BCL2L10 | 10017 | 5 | 7 | 41 | |
| GSE60625 | BCL2L10 | 10017 | 4 | 0 | 7 | |
| GSE74703 | BCL2L10 | 10017 | 4 | 2 | 30 | |
| GSE74704 | BCL2L10 | 10017 | 2 | 3 | 15 | |
| TCGA | BCL2L10 | 10017 | 9 | 17 | 70 |
Total number of gains: 54; Total number of losses: 63; Total Number of normals: 371.
Somatic mutations of BCL2L10:
Generating mutation plots.
Highly correlated genes for BCL2L10:
Showing top 20/344 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCL2L10 | LRTM1 | 0.765846 | 3 | 0 | 3 |
| BCL2L10 | PPP1R14D | 0.736724 | 4 | 0 | 3 |
| BCL2L10 | ARHGAP30 | 0.734602 | 3 | 0 | 3 |
| BCL2L10 | AGAP2 | 0.733898 | 4 | 0 | 4 |
| BCL2L10 | CEND1 | 0.730628 | 4 | 0 | 4 |
| BCL2L10 | ADAMTS13 | 0.721032 | 4 | 0 | 4 |
| BCL2L10 | FAM189A1 | 0.716356 | 3 | 0 | 3 |
| BCL2L10 | SLC22A7 | 0.710252 | 4 | 0 | 4 |
| BCL2L10 | NLRP13 | 0.709793 | 3 | 0 | 3 |
| BCL2L10 | SPTA1 | 0.698814 | 4 | 0 | 4 |
| BCL2L10 | DNAI1 | 0.691359 | 4 | 0 | 4 |
| BCL2L10 | CNPY1 | 0.691113 | 3 | 0 | 3 |
| BCL2L10 | ADAMTS7 | 0.691058 | 5 | 0 | 4 |
| BCL2L10 | GNB3 | 0.688204 | 4 | 0 | 4 |
| BCL2L10 | RBP4 | 0.687114 | 3 | 0 | 3 |
| BCL2L10 | ABCC6 | 0.684438 | 4 | 0 | 4 |
| BCL2L10 | KIF17 | 0.683652 | 4 | 0 | 3 |
| BCL2L10 | VCX2 | 0.68342 | 4 | 0 | 4 |
| BCL2L10 | NKX6-3 | 0.674593 | 3 | 0 | 3 |
| BCL2L10 | NCR3 | 0.671229 | 4 | 0 | 3 |
For details and further investigation, click here
