| Full name: ankyrin repeat domain 53 | Alias Symbol: FLJ12056|FLJ36160 | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 79998 | HGNC ID: HGNC:25691 | Ensembl Gene: ENSG00000144031 | OMIM ID: 617009 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKRD53:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKRD53 | 79998 | 244453_at | 0.0947 | 0.6937 | |
| GSE20347 | ANKRD53 | 79998 | 215759_at | -0.0817 | 0.1500 | |
| GSE23400 | ANKRD53 | 79998 | 215759_at | -0.1463 | 0.0000 | |
| GSE26886 | ANKRD53 | 79998 | 244453_at | 0.3164 | 0.0013 | |
| GSE29001 | ANKRD53 | 79998 | 215759_at | -0.0347 | 0.7830 | |
| GSE38129 | ANKRD53 | 79998 | 215759_at | -0.0870 | 0.1134 | |
| GSE45670 | ANKRD53 | 79998 | 244453_at | -0.0214 | 0.8252 | |
| GSE53622 | ANKRD53 | 79998 | 116241 | -0.1329 | 0.3370 | |
| GSE53624 | ANKRD53 | 79998 | 116241 | -0.0935 | 0.2961 | |
| GSE63941 | ANKRD53 | 79998 | 244453_at | 0.5468 | 0.0014 | |
| GSE77861 | ANKRD53 | 79998 | 244453_at | 0.0124 | 0.9286 | |
| GSE97050 | ANKRD53 | 79998 | A_24_P162979 | -0.1411 | 0.6790 | |
| SRP064894 | ANKRD53 | 79998 | RNAseq | -0.1429 | 0.7175 | |
| SRP133303 | ANKRD53 | 79998 | RNAseq | -0.8167 | 0.0122 | |
| SRP159526 | ANKRD53 | 79998 | RNAseq | 1.1188 | 0.1199 | |
| SRP219564 | ANKRD53 | 79998 | RNAseq | -0.3925 | 0.3088 | |
| TCGA | ANKRD53 | 79998 | RNAseq | -1.0650 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ANKRD53 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKRD53:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKRD53 | 79998 | 11 | 1 | 18 | |
| GSE20123 | ANKRD53 | 79998 | 11 | 1 | 18 | |
| GSE43470 | ANKRD53 | 79998 | 3 | 0 | 40 | |
| GSE46452 | ANKRD53 | 79998 | 2 | 3 | 54 | |
| GSE47630 | ANKRD53 | 79998 | 7 | 0 | 33 | |
| GSE54993 | ANKRD53 | 79998 | 0 | 6 | 64 | |
| GSE54994 | ANKRD53 | 79998 | 11 | 0 | 42 | |
| GSE60625 | ANKRD53 | 79998 | 0 | 3 | 8 | |
| GSE74703 | ANKRD53 | 79998 | 3 | 0 | 33 | |
| GSE74704 | ANKRD53 | 79998 | 9 | 0 | 11 | |
| TCGA | ANKRD53 | 79998 | 37 | 2 | 57 |
Total number of gains: 94; Total number of losses: 16; Total Number of normals: 378.
Somatic mutations of ANKRD53:
Generating mutation plots.
Highly correlated genes for ANKRD53:
Showing top 20/678 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKRD53 | GAS2L2 | 0.783496 | 3 | 0 | 3 |
| ANKRD53 | LINC00642 | 0.753352 | 3 | 0 | 3 |
| ANKRD53 | ZNF491 | 0.748465 | 3 | 0 | 3 |
| ANKRD53 | LRRC18 | 0.730934 | 3 | 0 | 3 |
| ANKRD53 | EMID1 | 0.714796 | 3 | 0 | 3 |
| ANKRD53 | MATN1 | 0.708282 | 3 | 0 | 3 |
| ANKRD53 | GTF2IRD2 | 0.699076 | 3 | 0 | 3 |
| ANKRD53 | ZNF511 | 0.695717 | 3 | 0 | 3 |
| ANKRD53 | SRRM5 | 0.694445 | 3 | 0 | 3 |
| ANKRD53 | KLHL35 | 0.692616 | 3 | 0 | 3 |
| ANKRD53 | DYNC1I1 | 0.692113 | 3 | 0 | 3 |
| ANKRD53 | PRAMEF12 | 0.691822 | 4 | 0 | 3 |
| ANKRD53 | GPBAR1 | 0.691362 | 4 | 0 | 3 |
| ANKRD53 | RENBP | 0.689697 | 4 | 0 | 4 |
| ANKRD53 | GLTPD2 | 0.687022 | 3 | 0 | 3 |
| ANKRD53 | TUT1 | 0.67852 | 4 | 0 | 4 |
| ANKRD53 | C2orf81 | 0.674042 | 4 | 0 | 4 |
| ANKRD53 | MOGAT3 | 0.67377 | 4 | 0 | 3 |
| ANKRD53 | C11orf86 | 0.670345 | 3 | 0 | 3 |
| ANKRD53 | OSM | 0.669986 | 4 | 0 | 4 |
For details and further investigation, click here
