| Full name: NOP2/Sun RNA methyltransferase family member 7 | Alias Symbol: FLJ14001 | ||
| Type: protein-coding gene | Cytoband: 4p14 | ||
| Entrez ID: 79730 | HGNC ID: HGNC:25857 | Ensembl Gene: ENSG00000179299 | OMIM ID: 617185 |
| Drug and gene relationship at DGIdb | |||
Expression of NSUN7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NSUN7 | 79730 | 238983_at | -0.3778 | 0.5455 | |
| GSE20347 | NSUN7 | 79730 | 220194_at | -0.1027 | 0.0750 | |
| GSE23400 | NSUN7 | 79730 | 220194_at | -0.1189 | 0.0003 | |
| GSE26886 | NSUN7 | 79730 | 238983_at | -0.0992 | 0.8425 | |
| GSE29001 | NSUN7 | 79730 | 220194_at | -0.1296 | 0.5217 | |
| GSE38129 | NSUN7 | 79730 | 220194_at | -0.1399 | 0.0082 | |
| GSE45670 | NSUN7 | 79730 | 238983_at | -0.9828 | 0.0265 | |
| GSE53622 | NSUN7 | 79730 | 54874 | -1.2232 | 0.0000 | |
| GSE53624 | NSUN7 | 79730 | 54874 | -1.3212 | 0.0000 | |
| GSE63941 | NSUN7 | 79730 | 238983_at | 1.5887 | 0.0874 | |
| GSE77861 | NSUN7 | 79730 | 238983_at | -0.2565 | 0.1019 | |
| GSE97050 | NSUN7 | 79730 | A_24_P7121 | -0.2801 | 0.4910 | |
| SRP007169 | NSUN7 | 79730 | RNAseq | -1.7653 | 0.0335 | |
| SRP064894 | NSUN7 | 79730 | RNAseq | -1.3517 | 0.0000 | |
| SRP133303 | NSUN7 | 79730 | RNAseq | -1.4008 | 0.0000 | |
| SRP159526 | NSUN7 | 79730 | RNAseq | -0.6681 | 0.2565 | |
| SRP193095 | NSUN7 | 79730 | RNAseq | -0.9457 | 0.0001 | |
| SRP219564 | NSUN7 | 79730 | RNAseq | -1.1575 | 0.0491 | |
| TCGA | NSUN7 | 79730 | RNAseq | -0.7810 | 0.0081 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by NSUN7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NSUN7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NSUN7 | 79730 | 1 | 16 | 13 | |
| GSE20123 | NSUN7 | 79730 | 1 | 16 | 13 | |
| GSE43470 | NSUN7 | 79730 | 0 | 14 | 29 | |
| GSE46452 | NSUN7 | 79730 | 1 | 36 | 22 | |
| GSE47630 | NSUN7 | 79730 | 1 | 19 | 20 | |
| GSE54993 | NSUN7 | 79730 | 7 | 0 | 63 | |
| GSE54994 | NSUN7 | 79730 | 4 | 10 | 39 | |
| GSE60625 | NSUN7 | 79730 | 0 | 0 | 11 | |
| GSE74703 | NSUN7 | 79730 | 0 | 12 | 24 | |
| GSE74704 | NSUN7 | 79730 | 0 | 9 | 11 | |
| TCGA | NSUN7 | 79730 | 11 | 44 | 41 |
Total number of gains: 26; Total number of losses: 176; Total Number of normals: 286.
Somatic mutations of NSUN7:
Generating mutation plots.
Highly correlated genes for NSUN7:
Showing top 20/272 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NSUN7 | MATN1 | 0.762301 | 3 | 0 | 3 |
| NSUN7 | AKAP3 | 0.680788 | 3 | 0 | 3 |
| NSUN7 | EDDM3A | 0.679483 | 3 | 0 | 3 |
| NSUN7 | HTR1E | 0.645639 | 5 | 0 | 5 |
| NSUN7 | TAS2R9 | 0.634394 | 3 | 0 | 3 |
| NSUN7 | GREB1L | 0.634248 | 4 | 0 | 3 |
| NSUN7 | MTAP | 0.631876 | 4 | 0 | 3 |
| NSUN7 | WDR78 | 0.6316 | 3 | 0 | 3 |
| NSUN7 | ACRV1 | 0.626107 | 4 | 0 | 3 |
| NSUN7 | AICDA | 0.621214 | 3 | 0 | 3 |
| NSUN7 | RBM20 | 0.62061 | 4 | 0 | 3 |
| NSUN7 | FCN2 | 0.6204 | 4 | 0 | 3 |
| NSUN7 | POU4F2 | 0.618135 | 3 | 0 | 3 |
| NSUN7 | ICA1 | 0.617164 | 8 | 0 | 6 |
| NSUN7 | EPS8L3 | 0.614444 | 5 | 0 | 4 |
| NSUN7 | SVIP | 0.614288 | 6 | 0 | 5 |
| NSUN7 | PPM1L | 0.614223 | 5 | 0 | 5 |
| NSUN7 | ART3 | 0.6092 | 3 | 0 | 3 |
| NSUN7 | SPICE1 | 0.604829 | 3 | 0 | 3 |
| NSUN7 | VWA7 | 0.60451 | 4 | 0 | 3 |
For details and further investigation, click here
