| Full name: midasin AAA ATPase 1 | Alias Symbol: KIAA0301|Rea1 | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 23195 | HGNC ID: HGNC:18302 | Ensembl Gene: ENSG00000112159 | OMIM ID: 618200 |
| Drug and gene relationship at DGIdb | |||
Expression of MDN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MDN1 | 23195 | 212693_at | 0.2066 | 0.5452 | |
| GSE20347 | MDN1 | 23195 | 212693_at | 0.1382 | 0.3534 | |
| GSE23400 | MDN1 | 23195 | 212693_at | 0.3330 | 0.0000 | |
| GSE26886 | MDN1 | 23195 | 212693_at | -0.5488 | 0.0524 | |
| GSE29001 | MDN1 | 23195 | 212693_at | 0.1898 | 0.5286 | |
| GSE38129 | MDN1 | 23195 | 212693_at | 0.1765 | 0.1631 | |
| GSE45670 | MDN1 | 23195 | 212693_at | 0.1265 | 0.3593 | |
| GSE53622 | MDN1 | 23195 | 51621 | -0.0841 | 0.3718 | |
| GSE53624 | MDN1 | 23195 | 51621 | 0.0409 | 0.6986 | |
| GSE63941 | MDN1 | 23195 | 212693_at | -0.0845 | 0.8491 | |
| GSE77861 | MDN1 | 23195 | 212693_at | 0.3468 | 0.2141 | |
| GSE97050 | MDN1 | 23195 | A_23_P365060 | 0.1126 | 0.5871 | |
| SRP007169 | MDN1 | 23195 | RNAseq | 1.6216 | 0.0002 | |
| SRP008496 | MDN1 | 23195 | RNAseq | 0.9236 | 0.0060 | |
| SRP064894 | MDN1 | 23195 | RNAseq | -0.1198 | 0.6457 | |
| SRP133303 | MDN1 | 23195 | RNAseq | -0.1711 | 0.2381 | |
| SRP159526 | MDN1 | 23195 | RNAseq | -0.1604 | 0.4773 | |
| SRP193095 | MDN1 | 23195 | RNAseq | 0.0379 | 0.7614 | |
| SRP219564 | MDN1 | 23195 | RNAseq | -0.3482 | 0.2402 | |
| TCGA | MDN1 | 23195 | RNAseq | -0.0638 | 0.1751 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MDN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MDN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MDN1 | 23195 | 1 | 4 | 25 | |
| GSE20123 | MDN1 | 23195 | 1 | 3 | 26 | |
| GSE43470 | MDN1 | 23195 | 2 | 1 | 40 | |
| GSE46452 | MDN1 | 23195 | 2 | 11 | 46 | |
| GSE47630 | MDN1 | 23195 | 8 | 6 | 26 | |
| GSE54993 | MDN1 | 23195 | 3 | 2 | 65 | |
| GSE54994 | MDN1 | 23195 | 8 | 10 | 35 | |
| GSE60625 | MDN1 | 23195 | 0 | 1 | 10 | |
| GSE74703 | MDN1 | 23195 | 2 | 1 | 33 | |
| GSE74704 | MDN1 | 23195 | 0 | 2 | 18 | |
| TCGA | MDN1 | 23195 | 6 | 21 | 69 |
Total number of gains: 33; Total number of losses: 62; Total Number of normals: 393.
Somatic mutations of MDN1:
Generating mutation plots.
Highly correlated genes for MDN1:
Showing top 20/409 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MDN1 | ZNF121 | 0.822839 | 3 | 0 | 3 |
| MDN1 | RLIM | 0.789702 | 3 | 0 | 3 |
| MDN1 | CDCA7 | 0.770855 | 3 | 0 | 3 |
| MDN1 | MED9 | 0.74851 | 3 | 0 | 3 |
| MDN1 | WDR37 | 0.743055 | 3 | 0 | 3 |
| MDN1 | TADA1 | 0.742503 | 3 | 0 | 3 |
| MDN1 | MSL1 | 0.739674 | 3 | 0 | 3 |
| MDN1 | NUP35 | 0.722986 | 4 | 0 | 4 |
| MDN1 | RTN3 | 0.721292 | 3 | 0 | 3 |
| MDN1 | ALS2 | 0.721191 | 3 | 0 | 3 |
| MDN1 | ARF1 | 0.71947 | 3 | 0 | 3 |
| MDN1 | WDR75 | 0.715583 | 4 | 0 | 3 |
| MDN1 | TERF2IP | 0.700869 | 3 | 0 | 3 |
| MDN1 | HEXA | 0.698462 | 3 | 0 | 3 |
| MDN1 | TATDN1 | 0.696321 | 4 | 0 | 3 |
| MDN1 | NEDD1 | 0.696175 | 3 | 0 | 3 |
| MDN1 | SNN | 0.692813 | 3 | 0 | 3 |
| MDN1 | LYPLAL1 | 0.690325 | 3 | 0 | 3 |
| MDN1 | IQCE | 0.690123 | 3 | 0 | 3 |
| MDN1 | TMEM237 | 0.689358 | 3 | 0 | 3 |
For details and further investigation, click here
