| Full name: lysophospholipase like 1 | Alias Symbol: Q96AV0 | ||
| Type: protein-coding gene | Cytoband: 1q41 | ||
| Entrez ID: 127018 | HGNC ID: HGNC:20440 | Ensembl Gene: ENSG00000143353 | OMIM ID: 616548 |
| Drug and gene relationship at DGIdb | |||
Expression of LYPLAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYPLAL1 | 127018 | 226851_at | -0.1852 | 0.6661 | |
| GSE26886 | LYPLAL1 | 127018 | 226851_at | 0.2017 | 0.5466 | |
| GSE45670 | LYPLAL1 | 127018 | 226851_at | 0.1312 | 0.4570 | |
| GSE53622 | LYPLAL1 | 127018 | 23413 | -0.5373 | 0.0000 | |
| GSE53624 | LYPLAL1 | 127018 | 23413 | -0.8565 | 0.0000 | |
| GSE63941 | LYPLAL1 | 127018 | 226851_at | 0.6401 | 0.1935 | |
| GSE77861 | LYPLAL1 | 127018 | 226851_at | -0.1356 | 0.7603 | |
| GSE97050 | LYPLAL1 | 127018 | A_33_P3352103 | -0.2570 | 0.2981 | |
| SRP007169 | LYPLAL1 | 127018 | RNAseq | -0.4666 | 0.3726 | |
| SRP008496 | LYPLAL1 | 127018 | RNAseq | -0.0165 | 0.9677 | |
| SRP064894 | LYPLAL1 | 127018 | RNAseq | -0.1000 | 0.4643 | |
| SRP133303 | LYPLAL1 | 127018 | RNAseq | 0.0641 | 0.7543 | |
| SRP159526 | LYPLAL1 | 127018 | RNAseq | -0.0051 | 0.9936 | |
| SRP193095 | LYPLAL1 | 127018 | RNAseq | -0.3149 | 0.0230 | |
| SRP219564 | LYPLAL1 | 127018 | RNAseq | -0.4632 | 0.0151 | |
| TCGA | LYPLAL1 | 127018 | RNAseq | 0.0111 | 0.9080 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LYPLAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYPLAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPLAL1 | 127018 | 9 | 0 | 21 | |
| GSE20123 | LYPLAL1 | 127018 | 8 | 0 | 22 | |
| GSE43470 | LYPLAL1 | 127018 | 8 | 1 | 34 | |
| GSE46452 | LYPLAL1 | 127018 | 3 | 1 | 55 | |
| GSE47630 | LYPLAL1 | 127018 | 15 | 0 | 25 | |
| GSE54993 | LYPLAL1 | 127018 | 0 | 6 | 64 | |
| GSE54994 | LYPLAL1 | 127018 | 15 | 0 | 38 | |
| GSE60625 | LYPLAL1 | 127018 | 0 | 0 | 11 | |
| GSE74703 | LYPLAL1 | 127018 | 8 | 1 | 27 | |
| GSE74704 | LYPLAL1 | 127018 | 2 | 0 | 18 | |
| TCGA | LYPLAL1 | 127018 | 45 | 3 | 48 |
Total number of gains: 113; Total number of losses: 12; Total Number of normals: 363.
Somatic mutations of LYPLAL1:
Generating mutation plots.
Highly correlated genes for LYPLAL1:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPLAL1 | HMGN3 | 0.816878 | 3 | 0 | 3 |
| LYPLAL1 | LYST | 0.807233 | 3 | 0 | 3 |
| LYPLAL1 | CIR1 | 0.802216 | 3 | 0 | 3 |
| LYPLAL1 | RPS4Y1 | 0.772288 | 3 | 0 | 3 |
| LYPLAL1 | SCAMP1 | 0.766661 | 3 | 0 | 3 |
| LYPLAL1 | RAD17 | 0.759972 | 3 | 0 | 3 |
| LYPLAL1 | RABGGTA | 0.748287 | 3 | 0 | 3 |
| LYPLAL1 | METAP2 | 0.733948 | 3 | 0 | 3 |
| LYPLAL1 | ENOSF1 | 0.726314 | 3 | 0 | 3 |
| LYPLAL1 | APPL1 | 0.721121 | 3 | 0 | 3 |
| LYPLAL1 | GOPC | 0.717945 | 3 | 0 | 3 |
| LYPLAL1 | CTDSPL | 0.714981 | 3 | 0 | 3 |
| LYPLAL1 | MRFAP1L1 | 0.710221 | 3 | 0 | 3 |
| LYPLAL1 | FBXL17 | 0.705415 | 4 | 0 | 4 |
| LYPLAL1 | NFIA | 0.701608 | 3 | 0 | 3 |
| LYPLAL1 | UBR3 | 0.697641 | 4 | 0 | 3 |
| LYPLAL1 | RGS7BP | 0.696759 | 3 | 0 | 3 |
| LYPLAL1 | IRAK1BP1 | 0.695108 | 3 | 0 | 3 |
| LYPLAL1 | VGLL4 | 0.694549 | 3 | 0 | 3 |
| LYPLAL1 | FAM149B1 | 0.693894 | 3 | 0 | 3 |
For details and further investigation, click here
