| Full name: mediator complex subunit 9 | Alias Symbol: FLJ10193|MED25 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 55090 | HGNC ID: HGNC:25487 | Ensembl Gene: ENSG00000141026 | OMIM ID: 609878 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MED9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MED9 | 55090 | 218372_at | 0.2258 | 0.1754 | |
| GSE20347 | MED9 | 55090 | 218372_at | 0.2377 | 0.0134 | |
| GSE23400 | MED9 | 55090 | 218372_at | 0.1096 | 0.0182 | |
| GSE26886 | MED9 | 55090 | 218372_at | 0.5596 | 0.0001 | |
| GSE29001 | MED9 | 55090 | 218372_at | 0.4288 | 0.0724 | |
| GSE38129 | MED9 | 55090 | 218372_at | 0.1812 | 0.0239 | |
| GSE45670 | MED9 | 55090 | 218372_at | 0.2674 | 0.0085 | |
| GSE53622 | MED9 | 55090 | 112728 | 0.3160 | 0.0000 | |
| GSE53624 | MED9 | 55090 | 112728 | 0.6642 | 0.0000 | |
| GSE63941 | MED9 | 55090 | 218372_at | 0.2753 | 0.5098 | |
| GSE77861 | MED9 | 55090 | 218372_at | 0.2053 | 0.3671 | |
| GSE97050 | MED9 | 55090 | A_23_P66402 | 0.0082 | 0.9801 | |
| SRP007169 | MED9 | 55090 | RNAseq | 0.7071 | 0.1615 | |
| SRP008496 | MED9 | 55090 | RNAseq | 0.4912 | 0.1161 | |
| SRP064894 | MED9 | 55090 | RNAseq | 0.9969 | 0.0000 | |
| SRP133303 | MED9 | 55090 | RNAseq | 0.6545 | 0.0000 | |
| SRP159526 | MED9 | 55090 | RNAseq | 0.9494 | 0.0001 | |
| SRP193095 | MED9 | 55090 | RNAseq | 0.3467 | 0.0060 | |
| SRP219564 | MED9 | 55090 | RNAseq | 0.7049 | 0.0996 | |
| TCGA | MED9 | 55090 | RNAseq | -0.0728 | 0.2435 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MED9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MED9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MED9 | 55090 | 3 | 3 | 24 | |
| GSE20123 | MED9 | 55090 | 3 | 4 | 23 | |
| GSE43470 | MED9 | 55090 | 1 | 5 | 37 | |
| GSE46452 | MED9 | 55090 | 34 | 1 | 24 | |
| GSE47630 | MED9 | 55090 | 7 | 1 | 32 | |
| GSE54993 | MED9 | 55090 | 3 | 3 | 64 | |
| GSE54994 | MED9 | 55090 | 6 | 5 | 42 | |
| GSE60625 | MED9 | 55090 | 4 | 0 | 7 | |
| GSE74703 | MED9 | 55090 | 1 | 2 | 33 | |
| GSE74704 | MED9 | 55090 | 2 | 1 | 17 | |
| TCGA | MED9 | 55090 | 18 | 23 | 55 |
Total number of gains: 82; Total number of losses: 48; Total Number of normals: 358.
Somatic mutations of MED9:
Generating mutation plots.
Highly correlated genes for MED9:
Showing top 20/1274 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MED9 | HMBOX1 | 0.821085 | 3 | 0 | 3 |
| MED9 | ROMO1 | 0.808096 | 3 | 0 | 3 |
| MED9 | BCL9L | 0.80639 | 3 | 0 | 3 |
| MED9 | TMEM63B | 0.789933 | 3 | 0 | 3 |
| MED9 | KRTCAP2 | 0.787739 | 4 | 0 | 4 |
| MED9 | CENPT | 0.783122 | 3 | 0 | 3 |
| MED9 | EVI5L | 0.771865 | 3 | 0 | 3 |
| MED9 | PKNOX1 | 0.762122 | 3 | 0 | 3 |
| MED9 | ZNF683 | 0.7605 | 3 | 0 | 3 |
| MED9 | TERF2 | 0.752777 | 3 | 0 | 3 |
| MED9 | EIF3G | 0.751104 | 3 | 0 | 3 |
| MED9 | FAM90A1 | 0.75052 | 3 | 0 | 3 |
| MED9 | MDN1 | 0.74851 | 3 | 0 | 3 |
| MED9 | GATAD2B | 0.746232 | 3 | 0 | 3 |
| MED9 | CHORDC1 | 0.744823 | 3 | 0 | 3 |
| MED9 | SAMD1 | 0.742467 | 5 | 0 | 4 |
| MED9 | XRRA1 | 0.730678 | 3 | 0 | 3 |
| MED9 | DRAP1 | 0.730266 | 3 | 0 | 3 |
| MED9 | CDKN2D | 0.724352 | 3 | 0 | 3 |
| MED9 | ZNF496 | 0.720852 | 5 | 0 | 5 |
For details and further investigation, click here
