| Full name: nucleoporin 35 | Alias Symbol: MP44 | ||
| Type: protein-coding gene | Cytoband: 2q32.1 | ||
| Entrez ID: 129401 | HGNC ID: HGNC:29797 | Ensembl Gene: ENSG00000163002 | OMIM ID: 608140 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUP35:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUP35 | 129401 | 225470_at | 0.7203 | 0.2311 | |
| GSE26886 | NUP35 | 129401 | 225470_at | -0.3175 | 0.3662 | |
| GSE45670 | NUP35 | 129401 | 225470_at | 0.4117 | 0.0248 | |
| GSE53622 | NUP35 | 129401 | 62705 | 0.2928 | 0.0001 | |
| GSE53624 | NUP35 | 129401 | 62705 | 0.5402 | 0.0000 | |
| GSE63941 | NUP35 | 129401 | 225470_at | 1.6537 | 0.0012 | |
| GSE77861 | NUP35 | 129401 | 225470_at | 0.6902 | 0.0162 | |
| GSE97050 | NUP35 | 129401 | A_23_P102320 | 0.3972 | 0.2837 | |
| SRP007169 | NUP35 | 129401 | RNAseq | 0.6616 | 0.1246 | |
| SRP008496 | NUP35 | 129401 | RNAseq | 0.9536 | 0.0001 | |
| SRP064894 | NUP35 | 129401 | RNAseq | 0.1514 | 0.5017 | |
| SRP133303 | NUP35 | 129401 | RNAseq | 0.3839 | 0.0103 | |
| SRP159526 | NUP35 | 129401 | RNAseq | 0.1821 | 0.4312 | |
| SRP193095 | NUP35 | 129401 | RNAseq | 0.3255 | 0.0509 | |
| SRP219564 | NUP35 | 129401 | RNAseq | 0.0267 | 0.9086 | |
| TCGA | NUP35 | 129401 | RNAseq | 0.1302 | 0.0449 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NUP35 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUP35:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUP35 | 129401 | 5 | 2 | 23 | |
| GSE20123 | NUP35 | 129401 | 5 | 2 | 23 | |
| GSE43470 | NUP35 | 129401 | 5 | 1 | 37 | |
| GSE46452 | NUP35 | 129401 | 1 | 4 | 54 | |
| GSE47630 | NUP35 | 129401 | 4 | 4 | 32 | |
| GSE54993 | NUP35 | 129401 | 0 | 5 | 65 | |
| GSE54994 | NUP35 | 129401 | 12 | 5 | 36 | |
| GSE60625 | NUP35 | 129401 | 0 | 3 | 8 | |
| GSE74703 | NUP35 | 129401 | 4 | 1 | 31 | |
| GSE74704 | NUP35 | 129401 | 2 | 2 | 16 | |
| TCGA | NUP35 | 129401 | 27 | 8 | 61 |
Total number of gains: 65; Total number of losses: 37; Total Number of normals: 386.
Somatic mutations of NUP35:
Generating mutation plots.
Highly correlated genes for NUP35:
Showing top 20/1123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUP35 | SMCHD1 | 0.826351 | 3 | 0 | 3 |
| NUP35 | INO80B | 0.822905 | 3 | 0 | 3 |
| NUP35 | CEBPZ | 0.807352 | 4 | 0 | 4 |
| NUP35 | NIPA2 | 0.799881 | 3 | 0 | 3 |
| NUP35 | DRAP1 | 0.790484 | 3 | 0 | 3 |
| NUP35 | TMEM135 | 0.786683 | 3 | 0 | 3 |
| NUP35 | GPR153 | 0.775788 | 3 | 0 | 3 |
| NUP35 | DSCC1 | 0.75823 | 5 | 0 | 5 |
| NUP35 | ANAPC1 | 0.751775 | 3 | 0 | 3 |
| NUP35 | RBMS1 | 0.751561 | 3 | 0 | 3 |
| NUP35 | ACBD6 | 0.750057 | 4 | 0 | 4 |
| NUP35 | FOXN2 | 0.748483 | 5 | 0 | 5 |
| NUP35 | CCDC86 | 0.741323 | 4 | 0 | 4 |
| NUP35 | HIBADH | 0.741068 | 3 | 0 | 3 |
| NUP35 | ASNSD1 | 0.73868 | 7 | 0 | 7 |
| NUP35 | C1orf112 | 0.737592 | 5 | 0 | 5 |
| NUP35 | FASTKD3 | 0.736448 | 3 | 0 | 3 |
| NUP35 | GSTO1 | 0.734955 | 3 | 0 | 3 |
| NUP35 | RUNX3 | 0.732024 | 3 | 0 | 3 |
| NUP35 | SUPT7L | 0.730998 | 4 | 0 | 3 |
For details and further investigation, click here
