MEGF8

 

Full name: multiple EGF like domains 8 Alias Symbol: SBP1|FLJ22365
Type: protein-coding gene Cytoband: 19q13.2
Entrez ID: 1954 HGNC ID: HGNC:3233 Ensembl Gene: ENSG00000105429 OMIM ID: 604267
Drug and gene relationship at DGIdb

 

Expression of MEGF8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MEGF8 1954 227327_at 0.2056 0.5150
GSE20347 MEGF8 1954 214778_at -0.1161 0.1288
GSE23400 MEGF8 1954 214778_at 0.0177 0.6503
GSE26886 MEGF8 1954 227327_at 0.1047 0.6198
GSE29001 MEGF8 1954 214778_at 0.1824 0.7557
GSE38129 MEGF8 1954 214778_at -0.1301 0.2762
GSE45670 MEGF8 1954 227327_at -0.0085 0.9491
GSE53622 MEGF8 1954 53141 -0.0160 0.8659
GSE53624 MEGF8 1954 53141 -0.1274 0.0607
GSE63941 MEGF8 1954 227327_at -0.6391 0.1026
GSE77861 MEGF8 1954 227327_at 0.0667 0.7427
GSE97050 MEGF8 1954 A_33_P3715177 -0.1876 0.4995
SRP007169 MEGF8 1954 RNAseq 0.0908 0.8417
SRP008496 MEGF8 1954 RNAseq -0.0480 0.9138
SRP064894 MEGF8 1954 RNAseq 0.6763 0.0058
SRP133303 MEGF8 1954 RNAseq -0.2414 0.2140
SRP159526 MEGF8 1954 RNAseq 0.6546 0.0383
SRP193095 MEGF8 1954 RNAseq 0.3059 0.0415
SRP219564 MEGF8 1954 RNAseq -0.3258 0.4928
TCGA MEGF8 1954 RNAseq -0.2834 0.0000

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MEGF8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MEGF8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MEGF8 1954 4 5 21
GSE20123 MEGF8 1954 4 4 22
GSE43470 MEGF8 1954 5 11 27
GSE46452 MEGF8 1954 47 1 11
GSE47630 MEGF8 1954 8 6 26
GSE54993 MEGF8 1954 17 4 49
GSE54994 MEGF8 1954 7 12 34
GSE60625 MEGF8 1954 9 0 2
GSE74703 MEGF8 1954 5 7 24
GSE74704 MEGF8 1954 4 2 14
TCGA MEGF8 1954 13 16 67

Total number of gains: 123; Total number of losses: 68; Total Number of normals: 297.  


 

Somatic mutations of MEGF8:

 

Generating mutation plots.

 

Highly correlated genes for MEGF8:

 

Showing top 20/123 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MEGF8C7orf610.72212303
MEGF8INF20.711004303
MEGF8FAM110B0.701177303
MEGF8SLC34A10.700685303
MEGF8ING50.694988303
MEGF8GTF2IRD20.693581303
MEGF8CACNA1H0.676302303
MEGF8RNF1230.675498303
MEGF8KIRREL20.67447303
MEGF8CPAMD80.673962403
MEGF8C16orf950.6737303
MEGF8CDH40.667248303
MEGF8ZFAT0.659403303
MEGF8SYNPO0.659087303
MEGF8TMEM120B0.656213403
MEGF8ITGB1BP20.655764303
MEGF8ZBTB480.655085303
MEGF8DOHH0.654689403
MEGF8IER5L0.651652403
MEGF8USP510.650285403

For details and further investigation, click here