| Full name: immediate early response 5 like | Alias Symbol: bA247A12.2 | ||
| Type: protein-coding gene | Cytoband: 9q34.11 | ||
| Entrez ID: 389792 | HGNC ID: HGNC:23679 | Ensembl Gene: ENSG00000188483 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IER5L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IER5L | 389792 | 226552_at | 0.3544 | 0.2257 | |
| GSE26886 | IER5L | 389792 | 226552_at | 1.0291 | 0.0004 | |
| GSE45670 | IER5L | 389792 | 226552_at | 0.5404 | 0.0053 | |
| GSE53622 | IER5L | 389792 | 53664 | 0.8699 | 0.0000 | |
| GSE53624 | IER5L | 389792 | 53664 | 1.1740 | 0.0000 | |
| GSE63941 | IER5L | 389792 | 226552_at | -1.0514 | 0.1381 | |
| GSE77861 | IER5L | 389792 | 226552_at | 0.1974 | 0.3036 | |
| GSE97050 | IER5L | 389792 | A_33_P3302312 | -0.0491 | 0.8633 | |
| SRP007169 | IER5L | 389792 | RNAseq | 1.4881 | 0.0024 | |
| SRP008496 | IER5L | 389792 | RNAseq | 1.2406 | 0.0010 | |
| SRP064894 | IER5L | 389792 | RNAseq | 2.2129 | 0.0000 | |
| SRP133303 | IER5L | 389792 | RNAseq | 1.0995 | 0.0000 | |
| SRP159526 | IER5L | 389792 | RNAseq | 1.1363 | 0.0074 | |
| SRP193095 | IER5L | 389792 | RNAseq | 1.2745 | 0.0000 | |
| SRP219564 | IER5L | 389792 | RNAseq | 0.6212 | 0.2113 | |
| TCGA | IER5L | 389792 | RNAseq | 0.3885 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by IER5L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IER5L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IER5L | 389792 | 6 | 9 | 15 | |
| GSE20123 | IER5L | 389792 | 6 | 9 | 15 | |
| GSE43470 | IER5L | 389792 | 5 | 8 | 30 | |
| GSE46452 | IER5L | 389792 | 6 | 13 | 40 | |
| GSE47630 | IER5L | 389792 | 3 | 16 | 21 | |
| GSE54993 | IER5L | 389792 | 3 | 3 | 64 | |
| GSE54994 | IER5L | 389792 | 11 | 8 | 34 | |
| GSE60625 | IER5L | 389792 | 0 | 0 | 11 | |
| GSE74703 | IER5L | 389792 | 5 | 6 | 25 | |
| GSE74704 | IER5L | 389792 | 3 | 7 | 10 | |
| TCGA | IER5L | 389792 | 27 | 25 | 44 |
Total number of gains: 75; Total number of losses: 104; Total Number of normals: 309.
Somatic mutations of IER5L:
Generating mutation plots.
Highly correlated genes for IER5L:
Showing top 20/368 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IER5L | NTNG2 | 0.789374 | 3 | 0 | 3 |
| IER5L | FOXE3 | 0.784595 | 3 | 0 | 3 |
| IER5L | ALX1 | 0.779911 | 3 | 0 | 3 |
| IER5L | ZNF133 | 0.779418 | 3 | 0 | 3 |
| IER5L | C19orf53 | 0.735161 | 3 | 0 | 3 |
| IER5L | ZNF446 | 0.730946 | 3 | 0 | 3 |
| IER5L | ASMTL | 0.723314 | 3 | 0 | 3 |
| IER5L | CDC34 | 0.722372 | 3 | 0 | 3 |
| IER5L | STAC3 | 0.721846 | 3 | 0 | 3 |
| IER5L | CHGB | 0.720328 | 3 | 0 | 3 |
| IER5L | COPS7B | 0.717564 | 3 | 0 | 3 |
| IER5L | PRDM13 | 0.717423 | 3 | 0 | 3 |
| IER5L | VAV2 | 0.698268 | 6 | 0 | 5 |
| IER5L | BAX | 0.692067 | 4 | 0 | 4 |
| IER5L | ZBTB24 | 0.684139 | 3 | 0 | 3 |
| IER5L | BCL2L12 | 0.68109 | 6 | 0 | 6 |
| IER5L | ZWINT | 0.679367 | 4 | 0 | 4 |
| IER5L | PMEPA1 | 0.675726 | 7 | 0 | 6 |
| IER5L | FBXO15 | 0.674761 | 3 | 0 | 3 |
| IER5L | TRIM17 | 0.670442 | 4 | 0 | 4 |
For details and further investigation, click here
