| Full name: calcium voltage-gated channel subunit alpha1 H | Alias Symbol: Cav3.2 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 8912 | HGNC ID: HGNC:1395 | Ensembl Gene: ENSG00000196557 | OMIM ID: 607904 |
| Drug and gene relationship at DGIdb | |||
CACNA1H involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04020 | Calcium signaling pathway | |
| hsa04713 | Circadian entrainment |
Expression of CACNA1H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACNA1H | 8912 | 205845_at | -0.5798 | 0.4187 | |
| GSE20347 | CACNA1H | 8912 | 205845_at | -0.1914 | 0.0594 | |
| GSE23400 | CACNA1H | 8912 | 205845_at | -0.3373 | 0.0000 | |
| GSE26886 | CACNA1H | 8912 | 222960_at | 0.4275 | 0.0100 | |
| GSE29001 | CACNA1H | 8912 | 205845_at | -0.2276 | 0.1616 | |
| GSE38129 | CACNA1H | 8912 | 205845_at | -0.4664 | 0.0031 | |
| GSE45670 | CACNA1H | 8912 | 205845_at | -0.1659 | 0.1405 | |
| GSE63941 | CACNA1H | 8912 | 222960_at | -0.0305 | 0.8300 | |
| GSE77861 | CACNA1H | 8912 | 222960_at | -0.0692 | 0.7337 | |
| GSE97050 | CACNA1H | 8912 | A_33_P3218960 | -0.6676 | 0.1889 | |
| SRP007169 | CACNA1H | 8912 | RNAseq | 3.0383 | 0.0023 | |
| SRP064894 | CACNA1H | 8912 | RNAseq | -0.1391 | 0.7340 | |
| SRP133303 | CACNA1H | 8912 | RNAseq | -0.6703 | 0.2157 | |
| SRP159526 | CACNA1H | 8912 | RNAseq | -0.9880 | 0.0722 | |
| SRP193095 | CACNA1H | 8912 | RNAseq | 0.8966 | 0.0291 | |
| SRP219564 | CACNA1H | 8912 | RNAseq | -0.7930 | 0.4121 | |
| TCGA | CACNA1H | 8912 | RNAseq | -0.7744 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CACNA1H expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CACNA1H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACNA1H | 8912 | 5 | 5 | 20 | |
| GSE20123 | CACNA1H | 8912 | 5 | 4 | 21 | |
| GSE43470 | CACNA1H | 8912 | 4 | 7 | 32 | |
| GSE46452 | CACNA1H | 8912 | 38 | 1 | 20 | |
| GSE47630 | CACNA1H | 8912 | 13 | 6 | 21 | |
| GSE54993 | CACNA1H | 8912 | 3 | 5 | 62 | |
| GSE54994 | CACNA1H | 8912 | 5 | 9 | 39 | |
| GSE60625 | CACNA1H | 8912 | 4 | 0 | 7 | |
| GSE74703 | CACNA1H | 8912 | 4 | 5 | 27 | |
| GSE74704 | CACNA1H | 8912 | 3 | 2 | 15 | |
| TCGA | CACNA1H | 8912 | 19 | 14 | 63 |
Total number of gains: 103; Total number of losses: 58; Total Number of normals: 327.
Somatic mutations of CACNA1H:
Generating mutation plots.
Highly correlated genes for CACNA1H:
Showing top 20/879 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACNA1H | STXBP6 | 0.843625 | 4 | 0 | 4 |
| CACNA1H | HMCN2 | 0.794619 | 3 | 0 | 3 |
| CACNA1H | NPY | 0.785637 | 6 | 0 | 6 |
| CACNA1H | PLIN4 | 0.782465 | 3 | 0 | 3 |
| CACNA1H | SFRP5 | 0.774362 | 3 | 0 | 3 |
| CACNA1H | GRIK3 | 0.765237 | 4 | 0 | 4 |
| CACNA1H | NKX6-1 | 0.763094 | 5 | 0 | 5 |
| CACNA1H | LAMA2 | 0.762186 | 4 | 0 | 4 |
| CACNA1H | STMN2 | 0.760604 | 5 | 0 | 5 |
| CACNA1H | CLIP3 | 0.757942 | 6 | 0 | 5 |
| CACNA1H | HMX1 | 0.757764 | 3 | 0 | 3 |
| CACNA1H | GDF2 | 0.750067 | 3 | 0 | 3 |
| CACNA1H | KCND3 | 0.749671 | 5 | 0 | 4 |
| CACNA1H | ADAMTSL3 | 0.748545 | 5 | 0 | 4 |
| CACNA1H | C9orf24 | 0.747733 | 3 | 0 | 3 |
| CACNA1H | PPP1R12A | 0.742539 | 3 | 0 | 3 |
| CACNA1H | FLNA | 0.738089 | 3 | 0 | 3 |
| CACNA1H | KCNC2 | 0.736427 | 3 | 0 | 3 |
| CACNA1H | FRRS1L | 0.736175 | 4 | 0 | 3 |
| CACNA1H | PPP3CB | 0.734535 | 3 | 0 | 3 |
For details and further investigation, click here
