ZBTB48

 

Full name: zinc finger and BTB domain containing 48 Alias Symbol: ZNF855|TZAP
Type: protein-coding gene Cytoband: 1p36.31
Entrez ID: 3104 HGNC ID: HGNC:4930 Ensembl Gene: ENSG00000204859 OMIM ID: 165270
Drug and gene relationship at DGIdb

 

Expression of ZBTB48:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZBTB48 3104 205025_at 0.5367 0.1957
GSE20347 ZBTB48 3104 205025_at 0.1594 0.2702
GSE23400 ZBTB48 3104 205025_at 0.1857 0.0004
GSE26886 ZBTB48 3104 205025_at 1.0302 0.0001
GSE29001 ZBTB48 3104 205025_at 0.0656 0.6863
GSE38129 ZBTB48 3104 205025_at 0.1676 0.1020
GSE45670 ZBTB48 3104 205025_at 0.3378 0.0016
GSE53622 ZBTB48 3104 94202 0.0428 0.2708
GSE53624 ZBTB48 3104 94202 -0.0124 0.8615
GSE63941 ZBTB48 3104 205025_at 1.1045 0.0034
GSE77861 ZBTB48 3104 205025_at 0.1108 0.7673
GSE97050 ZBTB48 3104 A_33_P3253264 -0.0664 0.7501
SRP007169 ZBTB48 3104 RNAseq -0.4794 0.3494
SRP064894 ZBTB48 3104 RNAseq 0.6254 0.0041
SRP133303 ZBTB48 3104 RNAseq -0.1898 0.1530
SRP159526 ZBTB48 3104 RNAseq 0.3364 0.3213
SRP193095 ZBTB48 3104 RNAseq 0.3732 0.0006
SRP219564 ZBTB48 3104 RNAseq 0.1253 0.6844
TCGA ZBTB48 3104 RNAseq -0.0313 0.6289

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by ZBTB48 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZBTB48:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZBTB48 3104 3 6 21
GSE20123 ZBTB48 3104 3 5 22
GSE43470 ZBTB48 3104 6 5 32
GSE46452 ZBTB48 3104 7 1 51
GSE47630 ZBTB48 3104 8 4 28
GSE54993 ZBTB48 3104 3 2 65
GSE54994 ZBTB48 3104 14 3 36
GSE60625 ZBTB48 3104 0 0 11
GSE74703 ZBTB48 3104 5 3 28
GSE74704 ZBTB48 3104 3 0 17
TCGA ZBTB48 3104 12 22 62

Total number of gains: 64; Total number of losses: 51; Total Number of normals: 373.  


 

Somatic mutations of ZBTB48:

 

Generating mutation plots.

 

Highly correlated genes for ZBTB48:

 

Showing top 20/310 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZBTB48OTUD50.846848303
ZBTB48FBRSL10.802647303
ZBTB48ISL20.772766303
ZBTB48SNORA71A0.730371303
ZBTB48ARL8A0.724671404
ZBTB48PYGO20.723439404
ZBTB48LRCH40.717207403
ZBTB48PRKAR1B0.708746303
ZBTB48SYCE1L0.704197404
ZBTB48C9orf1060.703168303
ZBTB48TP730.702188303
ZBTB48FAM24B0.701693403
ZBTB48MAPK150.698699303
ZBTB48BMP8B0.69721505
ZBTB48NRIP30.696237303
ZBTB48KRTAP4-10.690515303
ZBTB48CELF30.687125504
ZBTB48CCNL20.686819908
ZBTB48SLC35G10.685748303
ZBTB48C2orf810.685272303

For details and further investigation, click here