| Full name: methylphosphate capping enzyme | Alias Symbol: FLJ20257|MePCE | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 56257 | HGNC ID: HGNC:20247 | Ensembl Gene: ENSG00000146834 | OMIM ID: 611478 |
| Drug and gene relationship at DGIdb | |||
Expression of MEPCE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEPCE | 56257 | 219798_s_at | 0.6066 | 0.3592 | |
| GSE20347 | MEPCE | 56257 | 219798_s_at | 0.6090 | 0.0000 | |
| GSE23400 | MEPCE | 56257 | 219798_s_at | 0.2896 | 0.0000 | |
| GSE26886 | MEPCE | 56257 | 219798_s_at | 0.4781 | 0.0358 | |
| GSE29001 | MEPCE | 56257 | 219798_s_at | 0.4590 | 0.0087 | |
| GSE38129 | MEPCE | 56257 | 219798_s_at | 0.5219 | 0.0000 | |
| GSE45670 | MEPCE | 56257 | 219798_s_at | 0.4953 | 0.0035 | |
| GSE53622 | MEPCE | 56257 | 37834 | 0.5510 | 0.0000 | |
| GSE53624 | MEPCE | 56257 | 37834 | 0.6642 | 0.0000 | |
| GSE63941 | MEPCE | 56257 | 219798_s_at | 0.6540 | 0.1578 | |
| GSE77861 | MEPCE | 56257 | 219798_s_at | 0.2709 | 0.1437 | |
| GSE97050 | MEPCE | 56257 | A_24_P312189 | 0.1738 | 0.7043 | |
| SRP007169 | MEPCE | 56257 | RNAseq | 0.3916 | 0.2522 | |
| SRP008496 | MEPCE | 56257 | RNAseq | 0.5669 | 0.0542 | |
| SRP064894 | MEPCE | 56257 | RNAseq | 0.7750 | 0.0032 | |
| SRP133303 | MEPCE | 56257 | RNAseq | 0.3643 | 0.0078 | |
| SRP159526 | MEPCE | 56257 | RNAseq | 0.2403 | 0.2751 | |
| SRP193095 | MEPCE | 56257 | RNAseq | 0.5174 | 0.0020 | |
| SRP219564 | MEPCE | 56257 | RNAseq | 0.3163 | 0.4426 | |
| TCGA | MEPCE | 56257 | RNAseq | 0.0299 | 0.5608 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MEPCE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEPCE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEPCE | 56257 | 13 | 0 | 17 | |
| GSE20123 | MEPCE | 56257 | 13 | 0 | 17 | |
| GSE43470 | MEPCE | 56257 | 7 | 2 | 34 | |
| GSE46452 | MEPCE | 56257 | 11 | 1 | 47 | |
| GSE47630 | MEPCE | 56257 | 7 | 3 | 30 | |
| GSE54993 | MEPCE | 56257 | 1 | 9 | 60 | |
| GSE54994 | MEPCE | 56257 | 16 | 3 | 34 | |
| GSE60625 | MEPCE | 56257 | 0 | 0 | 11 | |
| GSE74703 | MEPCE | 56257 | 7 | 1 | 28 | |
| GSE74704 | MEPCE | 56257 | 9 | 0 | 11 | |
| TCGA | MEPCE | 56257 | 52 | 6 | 38 |
Total number of gains: 136; Total number of losses: 25; Total Number of normals: 327.
Somatic mutations of MEPCE:
Generating mutation plots.
Highly correlated genes for MEPCE:
Showing top 20/1341 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEPCE | TTLL1 | 0.795545 | 4 | 0 | 4 |
| MEPCE | GTPBP6 | 0.763099 | 3 | 0 | 3 |
| MEPCE | NSD1 | 0.762937 | 3 | 0 | 3 |
| MEPCE | ARL6IP4 | 0.759301 | 3 | 0 | 3 |
| MEPCE | PI4KA | 0.757228 | 3 | 0 | 3 |
| MEPCE | TAF6 | 0.751319 | 11 | 0 | 11 |
| MEPCE | EEF2 | 0.747891 | 3 | 0 | 3 |
| MEPCE | DAG1 | 0.738397 | 4 | 0 | 4 |
| MEPCE | MRI1 | 0.737107 | 3 | 0 | 3 |
| MEPCE | USP20 | 0.731664 | 3 | 0 | 3 |
| MEPCE | GFPT2 | 0.724186 | 3 | 0 | 3 |
| MEPCE | ZNF124 | 0.723971 | 3 | 0 | 3 |
| MEPCE | NXF1 | 0.720692 | 4 | 0 | 3 |
| MEPCE | FEM1A | 0.717208 | 3 | 0 | 3 |
| MEPCE | EFCAB7 | 0.717101 | 3 | 0 | 3 |
| MEPCE | ELOF1 | 0.715453 | 4 | 0 | 4 |
| MEPCE | ZNF32 | 0.712483 | 5 | 0 | 5 |
| MEPCE | ATXN2 | 0.709906 | 3 | 0 | 3 |
| MEPCE | STAT5A | 0.703319 | 3 | 0 | 3 |
| MEPCE | ZNF567 | 0.701732 | 3 | 0 | 3 |
For details and further investigation, click here
