| Full name: glutamine-fructose-6-phosphate transaminase 2 | Alias Symbol: GFAT2 | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 9945 | HGNC ID: HGNC:4242 | Ensembl Gene: ENSG00000131459 | OMIM ID: 603865 |
| Drug and gene relationship at DGIdb | |||
Expression of GFPT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GFPT2 | 9945 | 205100_at | -0.0786 | 0.9357 | |
| GSE20347 | GFPT2 | 9945 | 205100_at | 0.4258 | 0.0122 | |
| GSE23400 | GFPT2 | 9945 | 205100_at | 0.2699 | 0.0106 | |
| GSE26886 | GFPT2 | 9945 | 205100_at | 1.0690 | 0.0050 | |
| GSE29001 | GFPT2 | 9945 | 205100_at | 0.5948 | 0.0580 | |
| GSE38129 | GFPT2 | 9945 | 205100_at | 0.1311 | 0.6548 | |
| GSE45670 | GFPT2 | 9945 | 205100_at | -0.7276 | 0.1321 | |
| GSE53622 | GFPT2 | 9945 | 29570 | 0.8738 | 0.0002 | |
| GSE53624 | GFPT2 | 9945 | 29570 | 1.2200 | 0.0000 | |
| GSE63941 | GFPT2 | 9945 | 205100_at | -1.6251 | 0.2014 | |
| GSE77861 | GFPT2 | 9945 | 205100_at | 0.2868 | 0.1869 | |
| GSE97050 | GFPT2 | 9945 | A_23_P144916 | 1.0410 | 0.1084 | |
| SRP007169 | GFPT2 | 9945 | RNAseq | 3.7942 | 0.0000 | |
| SRP008496 | GFPT2 | 9945 | RNAseq | 2.9447 | 0.0000 | |
| SRP064894 | GFPT2 | 9945 | RNAseq | 0.3504 | 0.4169 | |
| SRP133303 | GFPT2 | 9945 | RNAseq | 1.8254 | 0.0006 | |
| SRP159526 | GFPT2 | 9945 | RNAseq | 0.4430 | 0.1898 | |
| SRP193095 | GFPT2 | 9945 | RNAseq | 3.4050 | 0.0000 | |
| SRP219564 | GFPT2 | 9945 | RNAseq | 1.1414 | 0.0765 | |
| TCGA | GFPT2 | 9945 | RNAseq | -0.0973 | 0.5680 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by GFPT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GFPT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GFPT2 | 9945 | 2 | 12 | 16 | |
| GSE20123 | GFPT2 | 9945 | 2 | 12 | 16 | |
| GSE43470 | GFPT2 | 9945 | 1 | 11 | 31 | |
| GSE46452 | GFPT2 | 9945 | 0 | 27 | 32 | |
| GSE47630 | GFPT2 | 9945 | 1 | 20 | 19 | |
| GSE54993 | GFPT2 | 9945 | 10 | 2 | 58 | |
| GSE54994 | GFPT2 | 9945 | 3 | 18 | 32 | |
| GSE60625 | GFPT2 | 9945 | 1 | 0 | 10 | |
| GSE74703 | GFPT2 | 9945 | 1 | 7 | 28 | |
| GSE74704 | GFPT2 | 9945 | 1 | 6 | 13 | |
| TCGA | GFPT2 | 9945 | 12 | 34 | 50 |
Total number of gains: 34; Total number of losses: 149; Total Number of normals: 305.
Somatic mutations of GFPT2:
Generating mutation plots.
Highly correlated genes for GFPT2:
Showing top 20/854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GFPT2 | PKN3 | 0.781973 | 3 | 0 | 3 |
| GFPT2 | FIBCD1 | 0.760634 | 3 | 0 | 3 |
| GFPT2 | LRRC8C | 0.750429 | 3 | 0 | 3 |
| GFPT2 | PPP1R35 | 0.742902 | 3 | 0 | 3 |
| GFPT2 | NEIL2 | 0.725812 | 3 | 0 | 3 |
| GFPT2 | MEPCE | 0.724186 | 3 | 0 | 3 |
| GFPT2 | PACS1 | 0.723093 | 4 | 0 | 3 |
| GFPT2 | FCGR3A | 0.717284 | 3 | 0 | 3 |
| GFPT2 | PARM1 | 0.716351 | 3 | 0 | 3 |
| GFPT2 | SEC61A2 | 0.715286 | 3 | 0 | 3 |
| GFPT2 | TRIM47 | 0.711095 | 4 | 0 | 3 |
| GFPT2 | CABIN1 | 0.711073 | 3 | 0 | 3 |
| GFPT2 | R3HDM2 | 0.710854 | 3 | 0 | 3 |
| GFPT2 | NFAM1 | 0.709686 | 3 | 0 | 3 |
| GFPT2 | POLRMT | 0.705809 | 3 | 0 | 3 |
| GFPT2 | FCHO1 | 0.701341 | 3 | 0 | 3 |
| GFPT2 | NNMT | 0.693918 | 4 | 0 | 4 |
| GFPT2 | PSEN2 | 0.693528 | 3 | 0 | 3 |
| GFPT2 | YBEY | 0.691596 | 3 | 0 | 3 |
| GFPT2 | ITIH6 | 0.686998 | 3 | 0 | 3 |
For details and further investigation, click here
