| Full name: ring finger protein 4 | Alias Symbol: RES4-26|SNURF|SLX5 | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 6047 | HGNC ID: HGNC:10067 | Ensembl Gene: ENSG00000063978 | OMIM ID: 602850 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RNF4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF4 | 6047 | 212696_s_at | 0.4848 | 0.0870 | |
| GSE20347 | RNF4 | 6047 | 212696_s_at | 0.0952 | 0.4210 | |
| GSE23400 | RNF4 | 6047 | 212696_s_at | 0.0299 | 0.5845 | |
| GSE26886 | RNF4 | 6047 | 212696_s_at | -0.1591 | 0.4386 | |
| GSE29001 | RNF4 | 6047 | 212696_s_at | 0.1338 | 0.5532 | |
| GSE38129 | RNF4 | 6047 | 212696_s_at | 0.1541 | 0.0541 | |
| GSE45670 | RNF4 | 6047 | 212696_s_at | -0.0108 | 0.9340 | |
| GSE63941 | RNF4 | 6047 | 212696_s_at | -0.1377 | 0.5942 | |
| GSE77861 | RNF4 | 6047 | 212696_s_at | 0.1062 | 0.5127 | |
| GSE97050 | RNF4 | 6047 | A_23_P167308 | 0.1689 | 0.3900 | |
| SRP007169 | RNF4 | 6047 | RNAseq | -0.5018 | 0.2087 | |
| SRP008496 | RNF4 | 6047 | RNAseq | -0.4478 | 0.0530 | |
| SRP064894 | RNF4 | 6047 | RNAseq | -0.0150 | 0.9291 | |
| SRP133303 | RNF4 | 6047 | RNAseq | 0.1298 | 0.2434 | |
| SRP159526 | RNF4 | 6047 | RNAseq | -0.0451 | 0.8072 | |
| SRP193095 | RNF4 | 6047 | RNAseq | -0.1743 | 0.0715 | |
| SRP219564 | RNF4 | 6047 | RNAseq | -0.0692 | 0.6948 | |
| TCGA | RNF4 | 6047 | RNAseq | -0.0681 | 0.1426 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RNF4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RNF4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF4 | 6047 | 0 | 16 | 14 | |
| GSE20123 | RNF4 | 6047 | 0 | 16 | 14 | |
| GSE43470 | RNF4 | 6047 | 0 | 17 | 26 | |
| GSE46452 | RNF4 | 6047 | 1 | 36 | 22 | |
| GSE47630 | RNF4 | 6047 | 1 | 19 | 20 | |
| GSE54993 | RNF4 | 6047 | 11 | 0 | 59 | |
| GSE54994 | RNF4 | 6047 | 3 | 12 | 38 | |
| GSE60625 | RNF4 | 6047 | 0 | 0 | 11 | |
| GSE74703 | RNF4 | 6047 | 0 | 13 | 23 | |
| GSE74704 | RNF4 | 6047 | 0 | 8 | 12 | |
| TCGA | RNF4 | 6047 | 8 | 49 | 39 |
Total number of gains: 24; Total number of losses: 186; Total Number of normals: 278.
Somatic mutations of RNF4:
Generating mutation plots.
Highly correlated genes for RNF4:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF4 | SLC1A5 | 0.832212 | 3 | 0 | 3 |
| RNF4 | WDR5 | 0.820733 | 3 | 0 | 3 |
| RNF4 | UHMK1 | 0.816654 | 3 | 0 | 3 |
| RNF4 | SP3 | 0.815843 | 3 | 0 | 3 |
| RNF4 | NUDT19 | 0.812595 | 3 | 0 | 3 |
| RNF4 | PACS1 | 0.803168 | 3 | 0 | 3 |
| RNF4 | PPP1R16A | 0.791857 | 3 | 0 | 3 |
| RNF4 | LIMK1 | 0.785494 | 3 | 0 | 3 |
| RNF4 | GPR153 | 0.785303 | 3 | 0 | 3 |
| RNF4 | MAP3K2 | 0.785144 | 3 | 0 | 3 |
| RNF4 | ORC2 | 0.774687 | 3 | 0 | 3 |
| RNF4 | PDCD2L | 0.774172 | 3 | 0 | 3 |
| RNF4 | SGSH | 0.77048 | 3 | 0 | 3 |
| RNF4 | GPATCH2 | 0.769717 | 3 | 0 | 3 |
| RNF4 | GK5 | 0.769361 | 3 | 0 | 3 |
| RNF4 | TOP1MT | 0.767482 | 3 | 0 | 3 |
| RNF4 | OCIAD2 | 0.765985 | 3 | 0 | 3 |
| RNF4 | SMYD2 | 0.764346 | 3 | 0 | 3 |
| RNF4 | BBS4 | 0.764162 | 3 | 0 | 3 |
| RNF4 | PDE7A | 0.763697 | 3 | 0 | 3 |
For details and further investigation, click here
