| Full name: glucosamine-phosphate N-acetyltransferase 1 | Alias Symbol: Gpnat1|FLJ10607 | ||
| Type: protein-coding gene | Cytoband: 14q22.1 | ||
| Entrez ID: 64841 | HGNC ID: HGNC:19980 | Ensembl Gene: ENSG00000100522 | OMIM ID: 616510 |
| Drug and gene relationship at DGIdb | |||
Expression of GNPNAT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GNPNAT1 | 64841 | 225853_at | 1.0241 | 0.1231 | |
| GSE26886 | GNPNAT1 | 64841 | 225853_at | 0.1947 | 0.3601 | |
| GSE45670 | GNPNAT1 | 64841 | 225853_at | 0.6294 | 0.0012 | |
| GSE63941 | GNPNAT1 | 64841 | 225853_at | 0.4705 | 0.3307 | |
| GSE77861 | GNPNAT1 | 64841 | 225853_at | 0.8252 | 0.0443 | |
| GSE97050 | GNPNAT1 | 64841 | A_23_P429184 | 0.3932 | 0.2000 | |
| SRP007169 | GNPNAT1 | 64841 | RNAseq | 0.9003 | 0.0384 | |
| SRP008496 | GNPNAT1 | 64841 | RNAseq | 0.8396 | 0.0019 | |
| SRP064894 | GNPNAT1 | 64841 | RNAseq | 0.5390 | 0.0015 | |
| SRP133303 | GNPNAT1 | 64841 | RNAseq | 0.5458 | 0.0015 | |
| SRP159526 | GNPNAT1 | 64841 | RNAseq | 0.2093 | 0.4218 | |
| SRP193095 | GNPNAT1 | 64841 | RNAseq | 0.0806 | 0.6246 | |
| SRP219564 | GNPNAT1 | 64841 | RNAseq | 0.8527 | 0.0502 | |
| TCGA | GNPNAT1 | 64841 | RNAseq | -0.0577 | 0.3405 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GNPNAT1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GNPNAT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GNPNAT1 | 64841 | 8 | 3 | 19 | |
| GSE20123 | GNPNAT1 | 64841 | 8 | 3 | 19 | |
| GSE43470 | GNPNAT1 | 64841 | 9 | 1 | 33 | |
| GSE46452 | GNPNAT1 | 64841 | 16 | 3 | 40 | |
| GSE47630 | GNPNAT1 | 64841 | 11 | 10 | 19 | |
| GSE54993 | GNPNAT1 | 64841 | 3 | 8 | 59 | |
| GSE54994 | GNPNAT1 | 64841 | 19 | 4 | 30 | |
| GSE60625 | GNPNAT1 | 64841 | 0 | 2 | 9 | |
| GSE74703 | GNPNAT1 | 64841 | 8 | 1 | 27 | |
| GSE74704 | GNPNAT1 | 64841 | 3 | 2 | 15 | |
| TCGA | GNPNAT1 | 64841 | 34 | 12 | 50 |
Total number of gains: 119; Total number of losses: 49; Total Number of normals: 320.
Somatic mutations of GNPNAT1:
Generating mutation plots.
Highly correlated genes for GNPNAT1:
Showing top 20/614 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GNPNAT1 | TBC1D31 | 0.798652 | 3 | 0 | 3 |
| GNPNAT1 | IL12RB2 | 0.79496 | 3 | 0 | 3 |
| GNPNAT1 | SLC52A2 | 0.788305 | 3 | 0 | 3 |
| GNPNAT1 | WDR5 | 0.778418 | 3 | 0 | 3 |
| GNPNAT1 | RBM28 | 0.775741 | 3 | 0 | 3 |
| GNPNAT1 | UTP14A | 0.762235 | 3 | 0 | 3 |
| GNPNAT1 | DAP3 | 0.760591 | 3 | 0 | 3 |
| GNPNAT1 | TMEM260 | 0.760507 | 3 | 0 | 3 |
| GNPNAT1 | MTERF3 | 0.760085 | 3 | 0 | 3 |
| GNPNAT1 | HMGB3 | 0.759192 | 3 | 0 | 3 |
| GNPNAT1 | SCARB1 | 0.75687 | 3 | 0 | 3 |
| GNPNAT1 | COLGALT1 | 0.755272 | 3 | 0 | 3 |
| GNPNAT1 | SLC38A6 | 0.753125 | 3 | 0 | 3 |
| GNPNAT1 | PUF60 | 0.750539 | 3 | 0 | 3 |
| GNPNAT1 | CHD1L | 0.747481 | 3 | 0 | 3 |
| GNPNAT1 | NUDCD1 | 0.74635 | 3 | 0 | 3 |
| GNPNAT1 | FZD6 | 0.744152 | 3 | 0 | 3 |
| GNPNAT1 | IMP4 | 0.743375 | 3 | 0 | 3 |
| GNPNAT1 | DNAJC2 | 0.738605 | 3 | 0 | 3 |
| GNPNAT1 | MRPS17 | 0.737436 | 4 | 0 | 4 |
For details and further investigation, click here
