| Full name: RAB2B, member RAS oncogene family | Alias Symbol: FLJ14824 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 84932 | HGNC ID: HGNC:20246 | Ensembl Gene: ENSG00000129472 | OMIM ID: 607466 |
| Drug and gene relationship at DGIdb | |||
Expression of RAB2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB2B | 84932 | 225074_at | 0.2433 | 0.7630 | |
| GSE26886 | RAB2B | 84932 | 225074_at | 0.1162 | 0.5725 | |
| GSE45670 | RAB2B | 84932 | 225074_at | 0.2390 | 0.0977 | |
| GSE53622 | RAB2B | 84932 | 21381 | 0.5995 | 0.0000 | |
| GSE53624 | RAB2B | 84932 | 21381 | 0.3510 | 0.0000 | |
| GSE63941 | RAB2B | 84932 | 225074_at | 0.3103 | 0.5170 | |
| GSE77861 | RAB2B | 84932 | 225074_at | 1.0055 | 0.0239 | |
| GSE97050 | RAB2B | 84932 | A_23_P65466 | 0.2063 | 0.4835 | |
| SRP007169 | RAB2B | 84932 | RNAseq | 0.6005 | 0.1193 | |
| SRP008496 | RAB2B | 84932 | RNAseq | 0.4995 | 0.0874 | |
| SRP064894 | RAB2B | 84932 | RNAseq | 0.5122 | 0.0001 | |
| SRP133303 | RAB2B | 84932 | RNAseq | 0.6959 | 0.0289 | |
| SRP159526 | RAB2B | 84932 | RNAseq | 0.3140 | 0.0373 | |
| SRP193095 | RAB2B | 84932 | RNAseq | 0.3441 | 0.0003 | |
| SRP219564 | RAB2B | 84932 | RNAseq | 0.2127 | 0.3696 | |
| TCGA | RAB2B | 84932 | RNAseq | 0.0310 | 0.5796 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RAB2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB2B | 84932 | 9 | 3 | 18 | |
| GSE20123 | RAB2B | 84932 | 9 | 3 | 18 | |
| GSE43470 | RAB2B | 84932 | 7 | 2 | 34 | |
| GSE46452 | RAB2B | 84932 | 18 | 2 | 39 | |
| GSE47630 | RAB2B | 84932 | 10 | 10 | 20 | |
| GSE54993 | RAB2B | 84932 | 3 | 11 | 56 | |
| GSE54994 | RAB2B | 84932 | 18 | 5 | 30 | |
| GSE60625 | RAB2B | 84932 | 0 | 2 | 9 | |
| GSE74703 | RAB2B | 84932 | 6 | 2 | 28 | |
| GSE74704 | RAB2B | 84932 | 4 | 2 | 14 | |
| TCGA | RAB2B | 84932 | 27 | 16 | 53 |
Total number of gains: 111; Total number of losses: 58; Total Number of normals: 319.
Somatic mutations of RAB2B:
Generating mutation plots.
Highly correlated genes for RAB2B:
Showing top 20/566 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB2B | HNRNPM | 0.796381 | 3 | 0 | 3 |
| RAB2B | DLGAP4 | 0.780179 | 3 | 0 | 3 |
| RAB2B | CCT4 | 0.773515 | 3 | 0 | 3 |
| RAB2B | BOD1 | 0.773247 | 3 | 0 | 3 |
| RAB2B | ASS1 | 0.763387 | 3 | 0 | 3 |
| RAB2B | FAM192A | 0.744482 | 3 | 0 | 3 |
| RAB2B | EIF3G | 0.730889 | 4 | 0 | 4 |
| RAB2B | AKR1B1 | 0.73052 | 3 | 0 | 3 |
| RAB2B | TOX4 | 0.727934 | 5 | 0 | 5 |
| RAB2B | LMF2 | 0.726385 | 3 | 0 | 3 |
| RAB2B | SUPT16H | 0.723599 | 8 | 0 | 6 |
| RAB2B | ANPEP | 0.719444 | 3 | 0 | 3 |
| RAB2B | NIPA1 | 0.716559 | 3 | 0 | 3 |
| RAB2B | MLEC | 0.705498 | 3 | 0 | 3 |
| RAB2B | TMEM184B | 0.701721 | 4 | 0 | 4 |
| RAB2B | EPPK1 | 0.700743 | 3 | 0 | 3 |
| RAB2B | CEP170 | 0.700282 | 3 | 0 | 3 |
| RAB2B | PSMC1 | 0.700187 | 5 | 0 | 5 |
| RAB2B | FXR1 | 0.697138 | 4 | 0 | 4 |
| RAB2B | KHNYN | 0.696304 | 4 | 0 | 3 |
For details and further investigation, click here
