| Full name: family with sequence similarity 149 member B1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 317662 | HGNC ID: HGNC:29162 | Ensembl Gene: ENSG00000138286 | OMIM ID: 618413 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM149B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM149B1 | 317662 | 213463_s_at | -0.7409 | 0.0343 | |
| GSE20347 | FAM149B1 | 317662 | 213463_s_at | -0.8451 | 0.0000 | |
| GSE23400 | FAM149B1 | 317662 | 213463_s_at | -0.1774 | 0.0000 | |
| GSE26886 | FAM149B1 | 317662 | 213463_s_at | -1.2625 | 0.0000 | |
| GSE29001 | FAM149B1 | 317662 | 213463_s_at | -1.0360 | 0.0009 | |
| GSE38129 | FAM149B1 | 317662 | 213463_s_at | -0.8445 | 0.0000 | |
| GSE45670 | FAM149B1 | 317662 | 213463_s_at | -0.5918 | 0.0006 | |
| GSE53622 | FAM149B1 | 317662 | 43066 | -0.5080 | 0.0000 | |
| GSE53624 | FAM149B1 | 317662 | 43066 | -0.6505 | 0.0000 | |
| GSE63941 | FAM149B1 | 317662 | 213463_s_at | -0.8555 | 0.1430 | |
| GSE77861 | FAM149B1 | 317662 | 213463_s_at | -0.4983 | 0.0060 | |
| GSE97050 | FAM149B1 | 317662 | A_33_P3422679 | -0.3684 | 0.2559 | |
| SRP007169 | FAM149B1 | 317662 | RNAseq | -1.3561 | 0.0007 | |
| SRP008496 | FAM149B1 | 317662 | RNAseq | -1.1180 | 0.0000 | |
| SRP064894 | FAM149B1 | 317662 | RNAseq | -0.3816 | 0.0052 | |
| SRP133303 | FAM149B1 | 317662 | RNAseq | -0.2035 | 0.1566 | |
| SRP159526 | FAM149B1 | 317662 | RNAseq | -0.7499 | 0.0002 | |
| SRP193095 | FAM149B1 | 317662 | RNAseq | -0.5602 | 0.0000 | |
| SRP219564 | FAM149B1 | 317662 | RNAseq | -0.5422 | 0.0047 | |
| TCGA | FAM149B1 | 317662 | RNAseq | -0.2286 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by FAM149B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM149B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM149B1 | 317662 | 3 | 4 | 23 | |
| GSE20123 | FAM149B1 | 317662 | 3 | 3 | 24 | |
| GSE43470 | FAM149B1 | 317662 | 1 | 8 | 34 | |
| GSE46452 | FAM149B1 | 317662 | 0 | 11 | 48 | |
| GSE47630 | FAM149B1 | 317662 | 2 | 14 | 24 | |
| GSE54993 | FAM149B1 | 317662 | 7 | 0 | 63 | |
| GSE54994 | FAM149B1 | 317662 | 2 | 10 | 41 | |
| GSE60625 | FAM149B1 | 317662 | 0 | 0 | 11 | |
| GSE74703 | FAM149B1 | 317662 | 1 | 5 | 30 | |
| GSE74704 | FAM149B1 | 317662 | 1 | 1 | 18 | |
| TCGA | FAM149B1 | 317662 | 11 | 23 | 62 |
Total number of gains: 31; Total number of losses: 79; Total Number of normals: 378.
Somatic mutations of FAM149B1:
Generating mutation plots.
Highly correlated genes for FAM149B1:
Showing top 20/1732 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM149B1 | SLC35B3 | 0.817624 | 3 | 0 | 3 |
| FAM149B1 | ZNF436 | 0.803315 | 4 | 0 | 4 |
| FAM149B1 | ZNF540 | 0.788042 | 3 | 0 | 3 |
| FAM149B1 | GALNT11 | 0.746623 | 4 | 0 | 4 |
| FAM149B1 | USP9Y | 0.746536 | 3 | 0 | 3 |
| FAM149B1 | EIF4E3 | 0.746215 | 8 | 0 | 7 |
| FAM149B1 | KDM5D | 0.742303 | 3 | 0 | 3 |
| FAM149B1 | RHBDF1 | 0.73372 | 5 | 0 | 5 |
| FAM149B1 | CRYL1 | 0.731135 | 11 | 0 | 10 |
| FAM149B1 | DLG2 | 0.730691 | 10 | 0 | 9 |
| FAM149B1 | FBXL3 | 0.726057 | 5 | 0 | 4 |
| FAM149B1 | RAB40AL | 0.723352 | 3 | 0 | 3 |
| FAM149B1 | SORT1 | 0.723258 | 11 | 0 | 11 |
| FAM149B1 | CCSER2 | 0.719796 | 8 | 0 | 8 |
| FAM149B1 | PAIP2B | 0.719009 | 11 | 0 | 10 |
| FAM149B1 | UBQLN1 | 0.718774 | 3 | 0 | 3 |
| FAM149B1 | SLC25A27 | 0.717739 | 4 | 0 | 3 |
| FAM149B1 | FCER1A | 0.716841 | 10 | 0 | 10 |
| FAM149B1 | TMEM132C | 0.715122 | 3 | 0 | 3 |
| FAM149B1 | C3orf38 | 0.713734 | 5 | 0 | 4 |
For details and further investigation, click here
