| Full name: DExH-box helicase 30 | Alias Symbol: KIAA0890|FLJ11214 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 22907 | HGNC ID: HGNC:16716 | Ensembl Gene: ENSG00000132153 | OMIM ID: 616423 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DHX30:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX30 | 22907 | 212674_s_at | 0.3762 | 0.2569 | |
| GSE20347 | DHX30 | 22907 | 212674_s_at | 0.0309 | 0.8126 | |
| GSE23400 | DHX30 | 22907 | 212674_s_at | 0.0194 | 0.7433 | |
| GSE26886 | DHX30 | 22907 | 212674_s_at | 0.2603 | 0.0766 | |
| GSE29001 | DHX30 | 22907 | 212674_s_at | -0.0728 | 0.8302 | |
| GSE38129 | DHX30 | 22907 | 212674_s_at | 0.0356 | 0.7315 | |
| GSE45670 | DHX30 | 22907 | 212674_s_at | -0.0431 | 0.6890 | |
| GSE53622 | DHX30 | 22907 | 39324 | -0.0523 | 0.2840 | |
| GSE53624 | DHX30 | 22907 | 24127 | 0.0845 | 0.0946 | |
| GSE63941 | DHX30 | 22907 | 212674_s_at | -0.2868 | 0.3646 | |
| GSE77861 | DHX30 | 22907 | 239772_x_at | -0.2826 | 0.0295 | |
| GSE97050 | DHX30 | 22907 | A_33_P3383936 | 0.0984 | 0.6194 | |
| SRP007169 | DHX30 | 22907 | RNAseq | 0.1834 | 0.6932 | |
| SRP008496 | DHX30 | 22907 | RNAseq | 0.4023 | 0.1914 | |
| SRP064894 | DHX30 | 22907 | RNAseq | 0.2577 | 0.1007 | |
| SRP133303 | DHX30 | 22907 | RNAseq | -0.1572 | 0.2747 | |
| SRP159526 | DHX30 | 22907 | RNAseq | 0.3032 | 0.1708 | |
| SRP193095 | DHX30 | 22907 | RNAseq | 0.0648 | 0.4549 | |
| SRP219564 | DHX30 | 22907 | RNAseq | -0.0093 | 0.9808 | |
| TCGA | DHX30 | 22907 | RNAseq | -0.1029 | 0.0189 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DHX30 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX30:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX30 | 22907 | 0 | 18 | 12 | |
| GSE20123 | DHX30 | 22907 | 0 | 19 | 11 | |
| GSE43470 | DHX30 | 22907 | 0 | 19 | 24 | |
| GSE46452 | DHX30 | 22907 | 2 | 17 | 40 | |
| GSE47630 | DHX30 | 22907 | 2 | 23 | 15 | |
| GSE54993 | DHX30 | 22907 | 6 | 2 | 62 | |
| GSE54994 | DHX30 | 22907 | 0 | 36 | 17 | |
| GSE60625 | DHX30 | 22907 | 5 | 0 | 6 | |
| GSE74703 | DHX30 | 22907 | 0 | 15 | 21 | |
| GSE74704 | DHX30 | 22907 | 0 | 12 | 8 | |
| TCGA | DHX30 | 22907 | 0 | 76 | 20 |
Total number of gains: 15; Total number of losses: 237; Total Number of normals: 236.
Somatic mutations of DHX30:
Generating mutation plots.
Highly correlated genes for DHX30:
Showing top 20/246 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX30 | ZNF641 | 0.786784 | 3 | 0 | 3 |
| DHX30 | ZNF736 | 0.770543 | 3 | 0 | 3 |
| DHX30 | ZNF41 | 0.737446 | 3 | 0 | 3 |
| DHX30 | ZNF251 | 0.735468 | 3 | 0 | 3 |
| DHX30 | ZNF579 | 0.73456 | 4 | 0 | 4 |
| DHX30 | KRI1 | 0.733263 | 3 | 0 | 3 |
| DHX30 | CHD3 | 0.730749 | 3 | 0 | 3 |
| DHX30 | PTBP1 | 0.727619 | 3 | 0 | 3 |
| DHX30 | HGS | 0.727325 | 3 | 0 | 3 |
| DHX30 | SAMD3 | 0.725864 | 3 | 0 | 3 |
| DHX30 | CISD3 | 0.723729 | 3 | 0 | 3 |
| DHX30 | ZNF155 | 0.721595 | 3 | 0 | 3 |
| DHX30 | EFCAB7 | 0.719493 | 3 | 0 | 3 |
| DHX30 | NMD3 | 0.717634 | 3 | 0 | 3 |
| DHX30 | CLCN7 | 0.717578 | 3 | 0 | 3 |
| DHX30 | KRR1 | 0.715491 | 3 | 0 | 3 |
| DHX30 | SKI | 0.715302 | 4 | 0 | 3 |
| DHX30 | MLLT6 | 0.713613 | 3 | 0 | 3 |
| DHX30 | POLDIP3 | 0.710054 | 3 | 0 | 3 |
| DHX30 | BAG6 | 0.707803 | 5 | 0 | 5 |
For details and further investigation, click here
