| Full name: interferon regulatory factor 2 binding protein like | Alias Symbol: EAP1|KIAA1865 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 64207 | HGNC ID: HGNC:14282 | Ensembl Gene: ENSG00000119669 | OMIM ID: 611720 |
Screen Evidence:
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Expression of IRF2BPL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IRF2BPL | 64207 | 223474_at | 0.4830 | 0.1499 | |
| GSE26886 | IRF2BPL | 64207 | 223474_at | 0.3998 | 0.0356 | |
| GSE45670 | IRF2BPL | 64207 | 223474_at | -0.0801 | 0.7691 | |
| GSE53622 | IRF2BPL | 64207 | 128317 | 0.6460 | 0.0000 | |
| GSE53624 | IRF2BPL | 64207 | 128317 | 0.6248 | 0.0000 | |
| GSE63941 | IRF2BPL | 64207 | 223474_at | -0.2267 | 0.5061 | |
| GSE77861 | IRF2BPL | 64207 | 223474_at | 0.8709 | 0.0164 | |
| GSE97050 | IRF2BPL | 64207 | A_32_P466514 | 0.1483 | 0.7808 | |
| SRP007169 | IRF2BPL | 64207 | RNAseq | 0.6637 | 0.0472 | |
| SRP008496 | IRF2BPL | 64207 | RNAseq | 0.6749 | 0.0010 | |
| SRP064894 | IRF2BPL | 64207 | RNAseq | 0.3727 | 0.1131 | |
| SRP133303 | IRF2BPL | 64207 | RNAseq | 0.3400 | 0.0320 | |
| SRP159526 | IRF2BPL | 64207 | RNAseq | 1.2207 | 0.0007 | |
| SRP193095 | IRF2BPL | 64207 | RNAseq | 0.9216 | 0.0000 | |
| SRP219564 | IRF2BPL | 64207 | RNAseq | 0.2888 | 0.4926 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IRF2BPL expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of IRF2BPL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IRF2BPL | 64207 | 8 | 3 | 19 | |
| GSE20123 | IRF2BPL | 64207 | 8 | 3 | 19 | |
| GSE43470 | IRF2BPL | 64207 | 8 | 3 | 32 | |
| GSE46452 | IRF2BPL | 64207 | 16 | 3 | 40 | |
| GSE47630 | IRF2BPL | 64207 | 11 | 8 | 21 | |
| GSE54993 | IRF2BPL | 64207 | 3 | 8 | 59 | |
| GSE54994 | IRF2BPL | 64207 | 19 | 4 | 30 | |
| GSE60625 | IRF2BPL | 64207 | 0 | 2 | 9 | |
| GSE74703 | IRF2BPL | 64207 | 7 | 3 | 26 | |
| GSE74704 | IRF2BPL | 64207 | 3 | 3 | 14 | |
| TCGA | IRF2BPL | 64207 | 33 | 15 | 48 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of IRF2BPL:
Generating mutation plots.
Highly correlated genes for IRF2BPL:
Showing top 20/1237 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IRF2BPL | TUBA1B | 0.879137 | 3 | 0 | 3 |
| IRF2BPL | SLC39A1 | 0.861984 | 3 | 0 | 3 |
| IRF2BPL | CBL | 0.843708 | 3 | 0 | 3 |
| IRF2BPL | FEZ2 | 0.833945 | 3 | 0 | 3 |
| IRF2BPL | HRH1 | 0.821769 | 3 | 0 | 3 |
| IRF2BPL | DDX28 | 0.818183 | 3 | 0 | 3 |
| IRF2BPL | CERS2 | 0.809661 | 3 | 0 | 3 |
| IRF2BPL | ADAR | 0.803498 | 3 | 0 | 3 |
| IRF2BPL | CSNK2A2 | 0.802323 | 3 | 0 | 3 |
| IRF2BPL | ZFHX3 | 0.794681 | 4 | 0 | 4 |
| IRF2BPL | SPATA5 | 0.7915 | 3 | 0 | 3 |
| IRF2BPL | GAS2L1 | 0.790083 | 3 | 0 | 3 |
| IRF2BPL | DDB1 | 0.785621 | 3 | 0 | 3 |
| IRF2BPL | TMEM208 | 0.781486 | 3 | 0 | 3 |
| IRF2BPL | MPHOSPH6 | 0.780221 | 3 | 0 | 3 |
| IRF2BPL | RAB11FIP5 | 0.779318 | 3 | 0 | 3 |
| IRF2BPL | ATXN1L | 0.777163 | 3 | 0 | 3 |
| IRF2BPL | DOLK | 0.772313 | 3 | 0 | 3 |
| IRF2BPL | TRAP1 | 0.770387 | 3 | 0 | 3 |
| IRF2BPL | TFIP11 | 0.770043 | 3 | 0 | 3 |
For details and further investigation, click here
