| Full name: chaperonin containing TCP1 subunit 5 | Alias Symbol: KIAA0098 | ||
| Type: protein-coding gene | Cytoband: 5p15.2 | ||
| Entrez ID: 22948 | HGNC ID: HGNC:1618 | Ensembl Gene: ENSG00000150753 | OMIM ID: 610150 |
| Drug and gene relationship at DGIdb | |||
Expression of CCT5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCT5 | 22948 | 208696_at | 0.9922 | 0.0250 | |
| GSE20347 | CCT5 | 22948 | 208696_at | 0.8485 | 0.0000 | |
| GSE23400 | CCT5 | 22948 | 208696_at | 0.8734 | 0.0000 | |
| GSE26886 | CCT5 | 22948 | 208696_at | 0.1694 | 0.4687 | |
| GSE29001 | CCT5 | 22948 | 208696_at | 0.6971 | 0.0271 | |
| GSE38129 | CCT5 | 22948 | 208696_at | 1.0220 | 0.0000 | |
| GSE45670 | CCT5 | 22948 | 208696_at | 0.8054 | 0.0001 | |
| GSE63941 | CCT5 | 22948 | 208696_at | 0.9594 | 0.0025 | |
| GSE77861 | CCT5 | 22948 | 208696_at | 0.7458 | 0.0092 | |
| GSE97050 | CCT5 | 22948 | A_24_P328872 | 0.1472 | 0.5977 | |
| SRP007169 | CCT5 | 22948 | RNAseq | 0.8063 | 0.0075 | |
| SRP008496 | CCT5 | 22948 | RNAseq | 0.6025 | 0.0513 | |
| SRP064894 | CCT5 | 22948 | RNAseq | 0.6373 | 0.0007 | |
| SRP133303 | CCT5 | 22948 | RNAseq | 0.9358 | 0.0000 | |
| SRP159526 | CCT5 | 22948 | RNAseq | 0.9993 | 0.0145 | |
| SRP193095 | CCT5 | 22948 | RNAseq | 0.6665 | 0.0002 | |
| SRP219564 | CCT5 | 22948 | RNAseq | 0.7827 | 0.0504 | |
| TCGA | CCT5 | 22948 | RNAseq | 0.3364 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by CCT5 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CCT5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCT5 | 22948 | 12 | 0 | 18 | |
| GSE20123 | CCT5 | 22948 | 12 | 0 | 18 | |
| GSE43470 | CCT5 | 22948 | 18 | 0 | 25 | |
| GSE46452 | CCT5 | 22948 | 6 | 22 | 31 | |
| GSE47630 | CCT5 | 22948 | 6 | 11 | 23 | |
| GSE54993 | CCT5 | 22948 | 5 | 5 | 60 | |
| GSE54994 | CCT5 | 22948 | 29 | 1 | 23 | |
| GSE60625 | CCT5 | 22948 | 0 | 0 | 11 | |
| GSE74703 | CCT5 | 22948 | 14 | 0 | 22 | |
| GSE74704 | CCT5 | 22948 | 11 | 0 | 9 | |
| TCGA | CCT5 | 22948 | 58 | 3 | 35 |
Total number of gains: 171; Total number of losses: 42; Total Number of normals: 275.
Somatic mutations of CCT5:
Generating mutation plots.
Highly correlated genes for CCT5:
Showing top 20/1879 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCT5 | XPR1 | 0.816826 | 4 | 0 | 4 |
| CCT5 | TRIP13 | 0.812046 | 9 | 0 | 9 |
| CCT5 | UBE2C | 0.802451 | 9 | 0 | 9 |
| CCT5 | PNPT1 | 0.799745 | 3 | 0 | 3 |
| CCT5 | BUB1 | 0.793974 | 7 | 0 | 7 |
| CCT5 | PDIA6 | 0.787415 | 8 | 0 | 8 |
| CCT5 | NOL11 | 0.784754 | 8 | 0 | 8 |
| CCT5 | AURKB | 0.78375 | 8 | 0 | 8 |
| CCT5 | MCM6 | 0.779056 | 8 | 0 | 8 |
| CCT5 | KIF2C | 0.773597 | 8 | 0 | 8 |
| CCT5 | ECT2 | 0.771829 | 8 | 0 | 7 |
| CCT5 | UBE2T | 0.771309 | 5 | 0 | 5 |
| CCT5 | MCM4 | 0.771067 | 8 | 0 | 8 |
| CCT5 | AURKA | 0.766764 | 9 | 0 | 9 |
| CCT5 | MTHFD2 | 0.766253 | 8 | 0 | 7 |
| CCT5 | WDR66 | 0.762843 | 4 | 0 | 4 |
| CCT5 | NUP155 | 0.760319 | 10 | 0 | 9 |
| CCT5 | PTDSS1 | 0.759992 | 8 | 0 | 8 |
| CCT5 | CDC45 | 0.759983 | 8 | 0 | 8 |
| CCT5 | RTTN | 0.756622 | 3 | 0 | 3 |
For details and further investigation, click here
