| Full name: mitochondrial ribosomal protein L18 | Alias Symbol: HSPC071 | ||
| Type: protein-coding gene | Cytoband: 6q25.3 | ||
| Entrez ID: 29074 | HGNC ID: HGNC:14477 | Ensembl Gene: ENSG00000112110 | OMIM ID: 611831 |
Screen Evidence:
| |||
Expression of MRPL18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL18 | 29074 | 217907_at | 0.2134 | 0.5334 | |
| GSE20347 | MRPL18 | 29074 | 217907_at | 0.2631 | 0.0649 | |
| GSE23400 | MRPL18 | 29074 | 217907_at | 0.5783 | 0.0000 | |
| GSE26886 | MRPL18 | 29074 | 217907_at | -0.4293 | 0.0515 | |
| GSE29001 | MRPL18 | 29074 | 217907_at | 0.4005 | 0.1563 | |
| GSE38129 | MRPL18 | 29074 | 217907_at | 0.3730 | 0.0006 | |
| GSE45670 | MRPL18 | 29074 | 217907_at | 0.4107 | 0.0304 | |
| GSE53622 | MRPL18 | 29074 | 111709 | 0.3574 | 0.0000 | |
| GSE53624 | MRPL18 | 29074 | 111709 | 0.5006 | 0.0000 | |
| GSE63941 | MRPL18 | 29074 | 217907_at | 0.2345 | 0.5044 | |
| GSE77861 | MRPL18 | 29074 | 217907_at | 0.1574 | 0.2870 | |
| GSE97050 | MRPL18 | 29074 | A_23_P8339 | 0.3201 | 0.2586 | |
| SRP007169 | MRPL18 | 29074 | RNAseq | 0.0917 | 0.7733 | |
| SRP008496 | MRPL18 | 29074 | RNAseq | 0.1000 | 0.6375 | |
| SRP064894 | MRPL18 | 29074 | RNAseq | 0.3930 | 0.0345 | |
| SRP133303 | MRPL18 | 29074 | RNAseq | 0.4453 | 0.0034 | |
| SRP159526 | MRPL18 | 29074 | RNAseq | 0.0712 | 0.6693 | |
| SRP193095 | MRPL18 | 29074 | RNAseq | -0.1028 | 0.3784 | |
| SRP219564 | MRPL18 | 29074 | RNAseq | 0.1243 | 0.7223 | |
| TCGA | MRPL18 | 29074 | RNAseq | 0.1898 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL18 | 29074 | 1 | 5 | 24 | |
| GSE20123 | MRPL18 | 29074 | 1 | 4 | 25 | |
| GSE43470 | MRPL18 | 29074 | 4 | 0 | 39 | |
| GSE46452 | MRPL18 | 29074 | 3 | 10 | 46 | |
| GSE47630 | MRPL18 | 29074 | 9 | 4 | 27 | |
| GSE54993 | MRPL18 | 29074 | 3 | 2 | 65 | |
| GSE54994 | MRPL18 | 29074 | 8 | 8 | 37 | |
| GSE60625 | MRPL18 | 29074 | 0 | 1 | 10 | |
| GSE74703 | MRPL18 | 29074 | 4 | 0 | 32 | |
| GSE74704 | MRPL18 | 29074 | 0 | 2 | 18 | |
| TCGA | MRPL18 | 29074 | 13 | 22 | 61 |
Total number of gains: 46; Total number of losses: 58; Total Number of normals: 384.
Somatic mutations of MRPL18:
Generating mutation plots.
Highly correlated genes for MRPL18:
Showing top 20/948 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL18 | SRSF6 | 0.856591 | 3 | 0 | 3 |
| MRPL18 | MRI1 | 0.816999 | 3 | 0 | 3 |
| MRPL18 | ZNF664 | 0.78465 | 3 | 0 | 3 |
| MRPL18 | NAA30 | 0.784505 | 3 | 0 | 3 |
| MRPL18 | EIF3C | 0.746947 | 3 | 0 | 3 |
| MRPL18 | ZNF304 | 0.740617 | 3 | 0 | 3 |
| MRPL18 | ISY1 | 0.732353 | 3 | 0 | 3 |
| MRPL18 | ARF3 | 0.728777 | 3 | 0 | 3 |
| MRPL18 | RPP14 | 0.723739 | 3 | 0 | 3 |
| MRPL18 | NDUFV1 | 0.718267 | 4 | 0 | 4 |
| MRPL18 | CAMTA1 | 0.713716 | 3 | 0 | 3 |
| MRPL18 | CHORDC1 | 0.70984 | 4 | 0 | 4 |
| MRPL18 | TUBG1 | 0.709613 | 8 | 0 | 8 |
| MRPL18 | SLC35A5 | 0.705059 | 4 | 0 | 4 |
| MRPL18 | EP400 | 0.702616 | 4 | 0 | 3 |
| MRPL18 | RBM7 | 0.702525 | 3 | 0 | 3 |
| MRPL18 | DLG5 | 0.702268 | 3 | 0 | 3 |
| MRPL18 | CIAO1 | 0.697677 | 3 | 0 | 3 |
| MRPL18 | RNF26 | 0.697558 | 3 | 0 | 3 |
| MRPL18 | AP1M2 | 0.695126 | 3 | 0 | 3 |
For details and further investigation, click here
