| Full name: cysteine and histidine rich domain containing 1 | Alias Symbol: CHP1|CHP-1 | ||
| Type: protein-coding gene | Cytoband: 11q14.3 | ||
| Entrez ID: 26973 | HGNC ID: HGNC:14525 | Ensembl Gene: ENSG00000110172 | OMIM ID: 604353 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CHORDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHORDC1 | 26973 | 218566_s_at | 0.5005 | 0.1799 | |
| GSE20347 | CHORDC1 | 26973 | 218566_s_at | 0.6767 | 0.0191 | |
| GSE23400 | CHORDC1 | 26973 | 218566_s_at | 0.7196 | 0.0000 | |
| GSE26886 | CHORDC1 | 26973 | 218566_s_at | -0.2637 | 0.3313 | |
| GSE29001 | CHORDC1 | 26973 | 218566_s_at | 0.4246 | 0.1297 | |
| GSE38129 | CHORDC1 | 26973 | 218566_s_at | 0.6722 | 0.0030 | |
| GSE45670 | CHORDC1 | 26973 | 218566_s_at | 0.8870 | 0.0001 | |
| GSE53622 | CHORDC1 | 26973 | 113513 | 0.7239 | 0.0000 | |
| GSE53624 | CHORDC1 | 26973 | 113513 | 0.8075 | 0.0000 | |
| GSE63941 | CHORDC1 | 26973 | 218566_s_at | 0.0190 | 0.9774 | |
| GSE77861 | CHORDC1 | 26973 | 218566_s_at | 0.2051 | 0.6537 | |
| GSE97050 | CHORDC1 | 26973 | A_33_P3502037 | 0.1100 | 0.7954 | |
| SRP007169 | CHORDC1 | 26973 | RNAseq | 1.4018 | 0.0118 | |
| SRP008496 | CHORDC1 | 26973 | RNAseq | 1.2700 | 0.0001 | |
| SRP064894 | CHORDC1 | 26973 | RNAseq | 0.3891 | 0.1692 | |
| SRP133303 | CHORDC1 | 26973 | RNAseq | 0.6497 | 0.0002 | |
| SRP159526 | CHORDC1 | 26973 | RNAseq | 1.0076 | 0.0905 | |
| SRP193095 | CHORDC1 | 26973 | RNAseq | -0.0123 | 0.9268 | |
| SRP219564 | CHORDC1 | 26973 | RNAseq | 0.0952 | 0.8068 | |
| TCGA | CHORDC1 | 26973 | RNAseq | 0.2035 | 0.0019 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CHORDC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHORDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHORDC1 | 26973 | 3 | 10 | 17 | |
| GSE20123 | CHORDC1 | 26973 | 3 | 10 | 17 | |
| GSE43470 | CHORDC1 | 26973 | 3 | 4 | 36 | |
| GSE46452 | CHORDC1 | 26973 | 6 | 23 | 30 | |
| GSE47630 | CHORDC1 | 26973 | 2 | 19 | 19 | |
| GSE54993 | CHORDC1 | 26973 | 8 | 2 | 60 | |
| GSE54994 | CHORDC1 | 26973 | 5 | 19 | 29 | |
| GSE60625 | CHORDC1 | 26973 | 0 | 3 | 8 | |
| GSE74703 | CHORDC1 | 26973 | 2 | 3 | 31 | |
| GSE74704 | CHORDC1 | 26973 | 3 | 6 | 11 | |
| TCGA | CHORDC1 | 26973 | 14 | 40 | 42 |
Total number of gains: 49; Total number of losses: 139; Total Number of normals: 300.
Somatic mutations of CHORDC1:
Generating mutation plots.
Highly correlated genes for CHORDC1:
Showing top 20/799 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHORDC1 | SLC45A4 | 0.748382 | 3 | 0 | 3 |
| CHORDC1 | MED9 | 0.744823 | 3 | 0 | 3 |
| CHORDC1 | IGF2R | 0.716558 | 4 | 0 | 4 |
| CHORDC1 | CPNE2 | 0.710138 | 3 | 0 | 3 |
| CHORDC1 | MRPL18 | 0.70984 | 4 | 0 | 4 |
| CHORDC1 | EARS2 | 0.704221 | 3 | 0 | 3 |
| CHORDC1 | NDUFS6 | 0.697094 | 3 | 0 | 3 |
| CHORDC1 | ALG10 | 0.688249 | 4 | 0 | 4 |
| CHORDC1 | RELL2 | 0.687576 | 3 | 0 | 3 |
| CHORDC1 | SLC15A4 | 0.683248 | 3 | 0 | 3 |
| CHORDC1 | SUPT7L | 0.681626 | 7 | 0 | 7 |
| CHORDC1 | RAC3 | 0.678894 | 3 | 0 | 3 |
| CHORDC1 | NARS2 | 0.67541 | 9 | 0 | 7 |
| CHORDC1 | LSM4 | 0.672608 | 3 | 0 | 3 |
| CHORDC1 | FMNL2 | 0.668755 | 4 | 0 | 4 |
| CHORDC1 | B3GNT9 | 0.664751 | 4 | 0 | 3 |
| CHORDC1 | ADCY7 | 0.66403 | 3 | 0 | 3 |
| CHORDC1 | MED17 | 0.663489 | 11 | 0 | 9 |
| CHORDC1 | MB21D2 | 0.662914 | 3 | 0 | 3 |
| CHORDC1 | POC5 | 0.662157 | 3 | 0 | 3 |
For details and further investigation, click here
