| Full name: ribonuclease P/MRP subunit p14 | Alias Symbol: P14 | ||
| Type: protein-coding gene | Cytoband: 3p14.3 | ||
| Entrez ID: 11102 | HGNC ID: HGNC:30327 | Ensembl Gene: ENSG00000163684 | OMIM ID: 606112 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RPP14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPP14 | 11102 | 204245_s_at | 0.0644 | 0.8534 | |
| GSE20347 | RPP14 | 11102 | 204245_s_at | -0.1965 | 0.0561 | |
| GSE23400 | RPP14 | 11102 | 204245_s_at | -0.0666 | 0.1541 | |
| GSE26886 | RPP14 | 11102 | 227005_at | -0.2108 | 0.2486 | |
| GSE29001 | RPP14 | 11102 | 204245_s_at | 0.0124 | 0.9564 | |
| GSE38129 | RPP14 | 11102 | 204245_s_at | -0.1432 | 0.1625 | |
| GSE45670 | RPP14 | 11102 | 204245_s_at | -0.1091 | 0.1617 | |
| GSE53622 | RPP14 | 11102 | 91375 | -0.5469 | 0.0000 | |
| GSE53624 | RPP14 | 11102 | 91375 | -0.3854 | 0.0000 | |
| GSE63941 | RPP14 | 11102 | 204245_s_at | 0.4025 | 0.1287 | |
| GSE77861 | RPP14 | 11102 | 227005_at | 0.1210 | 0.5864 | |
| GSE97050 | RPP14 | 11102 | A_24_P839254 | -0.2606 | 0.3078 | |
| SRP007169 | RPP14 | 11102 | RNAseq | 0.6470 | 0.3475 | |
| SRP064894 | RPP14 | 11102 | RNAseq | -0.6168 | 0.0014 | |
| SRP133303 | RPP14 | 11102 | RNAseq | -0.3770 | 0.0028 | |
| SRP159526 | RPP14 | 11102 | RNAseq | -0.4436 | 0.0782 | |
| SRP193095 | RPP14 | 11102 | RNAseq | -0.3670 | 0.0000 | |
| SRP219564 | RPP14 | 11102 | RNAseq | -0.7469 | 0.0268 | |
| TCGA | RPP14 | 11102 | RNAseq | -0.2099 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPP14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPP14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPP14 | 11102 | 0 | 17 | 13 | |
| GSE20123 | RPP14 | 11102 | 0 | 18 | 12 | |
| GSE43470 | RPP14 | 11102 | 0 | 17 | 26 | |
| GSE46452 | RPP14 | 11102 | 2 | 17 | 40 | |
| GSE47630 | RPP14 | 11102 | 1 | 24 | 15 | |
| GSE54993 | RPP14 | 11102 | 6 | 2 | 62 | |
| GSE54994 | RPP14 | 11102 | 0 | 32 | 21 | |
| GSE60625 | RPP14 | 11102 | 5 | 0 | 6 | |
| GSE74703 | RPP14 | 11102 | 0 | 14 | 22 | |
| GSE74704 | RPP14 | 11102 | 0 | 11 | 9 | |
| TCGA | RPP14 | 11102 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 231; Total Number of normals: 243.
Somatic mutations of RPP14:
Generating mutation plots.
Highly correlated genes for RPP14:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPP14 | MTCP1 | 0.774711 | 3 | 0 | 3 |
| RPP14 | RASSF3 | 0.743038 | 3 | 0 | 3 |
| RPP14 | PI16 | 0.742544 | 3 | 0 | 3 |
| RPP14 | PDE8A | 0.736046 | 3 | 0 | 3 |
| RPP14 | HERPUD2 | 0.729247 | 3 | 0 | 3 |
| RPP14 | MRPL18 | 0.723739 | 3 | 0 | 3 |
| RPP14 | TRIM35 | 0.721538 | 3 | 0 | 3 |
| RPP14 | AVEN | 0.70503 | 3 | 0 | 3 |
| RPP14 | PHRF1 | 0.70224 | 3 | 0 | 3 |
| RPP14 | XKR4 | 0.697238 | 3 | 0 | 3 |
| RPP14 | ETS2 | 0.695478 | 3 | 0 | 3 |
| RPP14 | CLNS1A | 0.688134 | 3 | 0 | 3 |
| RPP14 | EIF4G2 | 0.685831 | 3 | 0 | 3 |
| RPP14 | GTF2A2 | 0.683158 | 3 | 0 | 3 |
| RPP14 | DCTN1 | 0.67785 | 3 | 0 | 3 |
| RPP14 | CPT1A | 0.67428 | 3 | 0 | 3 |
| RPP14 | LRIF1 | 0.672209 | 3 | 0 | 3 |
| RPP14 | SLC39A1 | 0.668393 | 4 | 0 | 3 |
| RPP14 | BABAM1 | 0.666484 | 3 | 0 | 3 |
| RPP14 | GRB2 | 0.662167 | 3 | 0 | 3 |
For details and further investigation, click here
