| Full name: discs large MAGUK scaffold protein 5 | Alias Symbol: P-dlg|KIAA0583 | ||
| Type: protein-coding gene | Cytoband: 10q22.3 | ||
| Entrez ID: 9231 | HGNC ID: HGNC:2904 | Ensembl Gene: ENSG00000151208 | OMIM ID: 604090 |
| Drug and gene relationship at DGIdb | |||
Expression of DLG5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLG5 | 9231 | 201681_s_at | -0.0262 | 0.9226 | |
| GSE20347 | DLG5 | 9231 | 201681_s_at | 0.0402 | 0.8690 | |
| GSE23400 | DLG5 | 9231 | 201681_s_at | 0.1772 | 0.0292 | |
| GSE26886 | DLG5 | 9231 | 201681_s_at | -0.0284 | 0.9323 | |
| GSE29001 | DLG5 | 9231 | 201681_s_at | 0.0768 | 0.8318 | |
| GSE38129 | DLG5 | 9231 | 201681_s_at | 0.1912 | 0.2306 | |
| GSE45670 | DLG5 | 9231 | 201681_s_at | 0.2443 | 0.0653 | |
| GSE53622 | DLG5 | 9231 | 55802 | 0.2084 | 0.0096 | |
| GSE53624 | DLG5 | 9231 | 55802 | 0.4439 | 0.0000 | |
| GSE63941 | DLG5 | 9231 | 201681_s_at | -0.0890 | 0.8429 | |
| GSE77861 | DLG5 | 9231 | 201681_s_at | 0.4970 | 0.0257 | |
| GSE97050 | DLG5 | 9231 | A_24_P129632 | -0.0374 | 0.9006 | |
| SRP007169 | DLG5 | 9231 | RNAseq | 1.0789 | 0.0053 | |
| SRP008496 | DLG5 | 9231 | RNAseq | 1.2775 | 0.0000 | |
| SRP064894 | DLG5 | 9231 | RNAseq | 0.1686 | 0.4624 | |
| SRP133303 | DLG5 | 9231 | RNAseq | 0.3081 | 0.0095 | |
| SRP159526 | DLG5 | 9231 | RNAseq | -0.0781 | 0.7836 | |
| SRP193095 | DLG5 | 9231 | RNAseq | 0.4261 | 0.0001 | |
| SRP219564 | DLG5 | 9231 | RNAseq | 0.6743 | 0.1151 | |
| TCGA | DLG5 | 9231 | RNAseq | 0.0614 | 0.2814 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DLG5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLG5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLG5 | 9231 | 3 | 5 | 22 | |
| GSE20123 | DLG5 | 9231 | 3 | 4 | 23 | |
| GSE43470 | DLG5 | 9231 | 1 | 7 | 35 | |
| GSE46452 | DLG5 | 9231 | 0 | 11 | 48 | |
| GSE47630 | DLG5 | 9231 | 2 | 14 | 24 | |
| GSE54993 | DLG5 | 9231 | 7 | 0 | 63 | |
| GSE54994 | DLG5 | 9231 | 1 | 11 | 41 | |
| GSE60625 | DLG5 | 9231 | 0 | 0 | 11 | |
| GSE74703 | DLG5 | 9231 | 1 | 4 | 31 | |
| GSE74704 | DLG5 | 9231 | 1 | 2 | 17 | |
| TCGA | DLG5 | 9231 | 10 | 24 | 62 |
Total number of gains: 29; Total number of losses: 82; Total Number of normals: 377.
Somatic mutations of DLG5:
Generating mutation plots.
Highly correlated genes for DLG5:
Showing top 20/199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLG5 | CUL1 | 0.80954 | 3 | 0 | 3 |
| DLG5 | TRUB1 | 0.804784 | 3 | 0 | 3 |
| DLG5 | BAD | 0.774364 | 3 | 0 | 3 |
| DLG5 | SLC37A3 | 0.772615 | 3 | 0 | 3 |
| DLG5 | KLHL13 | 0.755465 | 3 | 0 | 3 |
| DLG5 | AMMECR1L | 0.748678 | 3 | 0 | 3 |
| DLG5 | LRP4 | 0.747765 | 3 | 0 | 3 |
| DLG5 | RFX5 | 0.746931 | 3 | 0 | 3 |
| DLG5 | DNM1L | 0.746864 | 3 | 0 | 3 |
| DLG5 | UHMK1 | 0.743622 | 3 | 0 | 3 |
| DLG5 | PIK3R3 | 0.733092 | 3 | 0 | 3 |
| DLG5 | ARL5B | 0.729181 | 3 | 0 | 3 |
| DLG5 | PIAS2 | 0.728415 | 3 | 0 | 3 |
| DLG5 | PDLIM1 | 0.727644 | 3 | 0 | 3 |
| DLG5 | ZNF3 | 0.724713 | 3 | 0 | 3 |
| DLG5 | PIF1 | 0.723131 | 3 | 0 | 3 |
| DLG5 | CKAP5 | 0.716918 | 3 | 0 | 3 |
| DLG5 | ZMYM3 | 0.715412 | 3 | 0 | 3 |
| DLG5 | SARNP | 0.713281 | 3 | 0 | 3 |
| DLG5 | FAM98B | 0.71181 | 4 | 0 | 3 |
For details and further investigation, click here
