| Full name: mitochondrial ribosomal protein S16 | Alias Symbol: CGI-132 | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 51021 | HGNC ID: HGNC:14048 | Ensembl Gene: ENSG00000182180 | OMIM ID: 609204 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MRPS16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPS16 | 51021 | 218046_s_at | 0.0721 | 0.8557 | |
| GSE20347 | MRPS16 | 51021 | 218046_s_at | -0.0191 | 0.9004 | |
| GSE23400 | MRPS16 | 51021 | 218046_s_at | 0.0257 | 0.7068 | |
| GSE26886 | MRPS16 | 51021 | 218046_s_at | -0.6569 | 0.0090 | |
| GSE29001 | MRPS16 | 51021 | 218046_s_at | -0.0668 | 0.8443 | |
| GSE38129 | MRPS16 | 51021 | 218046_s_at | 0.1716 | 0.1895 | |
| GSE45670 | MRPS16 | 51021 | 218046_s_at | 0.1974 | 0.1789 | |
| GSE53622 | MRPS16 | 51021 | 69637 | 0.2981 | 0.0007 | |
| GSE53624 | MRPS16 | 51021 | 69637 | 0.2181 | 0.0014 | |
| GSE63941 | MRPS16 | 51021 | 218046_s_at | 0.8930 | 0.0047 | |
| GSE77861 | MRPS16 | 51021 | 218046_s_at | -0.2085 | 0.5539 | |
| GSE97050 | MRPS16 | 51021 | A_33_P3320393 | 0.1379 | 0.5437 | |
| SRP007169 | MRPS16 | 51021 | RNAseq | -0.5631 | 0.2313 | |
| SRP008496 | MRPS16 | 51021 | RNAseq | -0.2791 | 0.2587 | |
| SRP064894 | MRPS16 | 51021 | RNAseq | 0.1312 | 0.4697 | |
| SRP133303 | MRPS16 | 51021 | RNAseq | 0.1902 | 0.0900 | |
| SRP159526 | MRPS16 | 51021 | RNAseq | -0.0218 | 0.9351 | |
| SRP193095 | MRPS16 | 51021 | RNAseq | -0.2160 | 0.0175 | |
| SRP219564 | MRPS16 | 51021 | RNAseq | 0.0597 | 0.8455 | |
| TCGA | MRPS16 | 51021 | RNAseq | 0.0601 | 0.2109 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPS16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPS16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPS16 | 51021 | 3 | 4 | 23 | |
| GSE20123 | MRPS16 | 51021 | 3 | 3 | 24 | |
| GSE43470 | MRPS16 | 51021 | 1 | 8 | 34 | |
| GSE46452 | MRPS16 | 51021 | 0 | 11 | 48 | |
| GSE47630 | MRPS16 | 51021 | 2 | 14 | 24 | |
| GSE54993 | MRPS16 | 51021 | 7 | 0 | 63 | |
| GSE54994 | MRPS16 | 51021 | 2 | 10 | 41 | |
| GSE60625 | MRPS16 | 51021 | 0 | 0 | 11 | |
| GSE74703 | MRPS16 | 51021 | 1 | 5 | 30 | |
| GSE74704 | MRPS16 | 51021 | 1 | 1 | 18 | |
| TCGA | MRPS16 | 51021 | 11 | 23 | 62 |
Total number of gains: 31; Total number of losses: 79; Total Number of normals: 378.
Somatic mutations of MRPS16:
Generating mutation plots.
Highly correlated genes for MRPS16:
Showing top 20/201 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPS16 | VHL | 0.853699 | 3 | 0 | 3 |
| MRPS16 | YY2 | 0.839613 | 3 | 0 | 3 |
| MRPS16 | C9orf153 | 0.835916 | 3 | 0 | 3 |
| MRPS16 | DCDC1 | 0.82389 | 3 | 0 | 3 |
| MRPS16 | TTLL9 | 0.802123 | 3 | 0 | 3 |
| MRPS16 | PRSS38 | 0.797351 | 3 | 0 | 3 |
| MRPS16 | CHST10 | 0.790364 | 3 | 0 | 3 |
| MRPS16 | TXNDC2 | 0.785283 | 3 | 0 | 3 |
| MRPS16 | AKR7A3 | 0.782391 | 3 | 0 | 3 |
| MRPS16 | MRGPRG | 0.779538 | 3 | 0 | 3 |
| MRPS16 | GCLM | 0.777369 | 3 | 0 | 3 |
| MRPS16 | OR2T27 | 0.774916 | 3 | 0 | 3 |
| MRPS16 | BBC3 | 0.767065 | 3 | 0 | 3 |
| MRPS16 | KLF17 | 0.759975 | 4 | 0 | 3 |
| MRPS16 | STRC | 0.759792 | 3 | 0 | 3 |
| MRPS16 | OR2A5 | 0.758475 | 3 | 0 | 3 |
| MRPS16 | C1QL2 | 0.755936 | 3 | 0 | 3 |
| MRPS16 | OR2T1 | 0.755072 | 3 | 0 | 3 |
| MRPS16 | TRAPPC3L | 0.753694 | 3 | 0 | 3 |
| MRPS16 | KRTAP10-12 | 0.751943 | 3 | 0 | 3 |
For details and further investigation, click here
