MS4A5

 

Full name: membrane spanning 4-domains A5 Alias Symbol: CD20L2
Type: protein-coding gene Cytoband: 11q12.2
Entrez ID: 64232 HGNC ID: HGNC:13374 Ensembl Gene: ENSG00000166930 OMIM ID: 606499
Drug and gene relationship at DGIdb

 

Expression of MS4A5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MS4A5 64232 220790_s_at 0.2029 0.2617
GSE20347 MS4A5 64232 220790_s_at 0.0563 0.5067
GSE23400 MS4A5 64232 220790_s_at -0.0402 0.3304
GSE26886 MS4A5 64232 220790_s_at -0.1231 0.3807
GSE29001 MS4A5 64232 220790_s_at -0.1926 0.3355
GSE38129 MS4A5 64232 220790_s_at -0.0260 0.8037
GSE45670 MS4A5 64232 220790_s_at 0.0856 0.3636
GSE53622 MS4A5 64232 1740 -0.2031 0.2100
GSE53624 MS4A5 64232 1740 -0.0548 0.5536
GSE63941 MS4A5 64232 220790_s_at 0.0063 0.9756
GSE77861 MS4A5 64232 220790_s_at -0.0275 0.8403

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MS4A5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MS4A5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MS4A5 64232 2 5 23
GSE20123 MS4A5 64232 2 5 23
GSE43470 MS4A5 64232 2 5 36
GSE46452 MS4A5 64232 8 4 47
GSE47630 MS4A5 64232 3 8 29
GSE54993 MS4A5 64232 3 0 67
GSE54994 MS4A5 64232 5 5 43
GSE60625 MS4A5 64232 0 3 8
GSE74703 MS4A5 64232 2 3 31
GSE74704 MS4A5 64232 2 3 15
TCGA MS4A5 64232 15 10 71

Total number of gains: 44; Total number of losses: 51; Total Number of normals: 393.  


 

Somatic mutations of MS4A5:

 

Generating mutation plots.

 

Highly correlated genes for MS4A5:

 

Showing top 20/540 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MS4A5PRORY0.711609404
MS4A5CHRM20.70669505
MS4A5MOCS30.694941303
MS4A5KHDRBS20.690922404
MS4A5CDC25C0.688341404
MS4A5IL210.677583403
MS4A5IFNA70.665036505
MS4A5RIT20.663427303
MS4A5CTAGE10.662402404
MS4A5CNTF0.661828303
MS4A5IFNA100.660339505
MS4A5HS3ST20.65734403
MS4A5IFT1220.656933404
MS4A5BUB10.653801303
MS4A5KCNJ100.651313403
MS4A5ZNF4600.651242404
MS4A5ART40.651069404
MS4A5CELF30.650453303
MS4A5ZNF5070.648841404
MS4A5PRPS1L10.647317504

For details and further investigation, click here