| Full name: molybdenum cofactor synthesis 3 | Alias Symbol: UBA4|dJ914P20.3 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 27304 | HGNC ID: HGNC:15765 | Ensembl Gene: ENSG00000124217 | OMIM ID: 609277 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MOCS3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOCS3 | 27304 | 206141_at | 0.5606 | 0.2124 | |
| GSE20347 | MOCS3 | 27304 | 206141_at | 0.1009 | 0.2869 | |
| GSE23400 | MOCS3 | 27304 | 206141_at | -0.0277 | 0.4428 | |
| GSE26886 | MOCS3 | 27304 | 206141_at | -0.1790 | 0.3557 | |
| GSE29001 | MOCS3 | 27304 | 206141_at | -0.1064 | 0.3873 | |
| GSE38129 | MOCS3 | 27304 | 206141_at | 0.0929 | 0.3405 | |
| GSE45670 | MOCS3 | 27304 | 206141_at | 0.4391 | 0.0045 | |
| GSE53622 | MOCS3 | 27304 | 17176 | 0.0549 | 0.4783 | |
| GSE53624 | MOCS3 | 27304 | 17176 | 0.1567 | 0.0236 | |
| GSE63941 | MOCS3 | 27304 | 206141_at | 1.4789 | 0.0021 | |
| GSE77861 | MOCS3 | 27304 | 206141_at | -0.0311 | 0.7682 | |
| GSE97050 | MOCS3 | 27304 | A_33_P3350202 | -0.0535 | 0.8362 | |
| SRP007169 | MOCS3 | 27304 | RNAseq | -0.2673 | 0.5260 | |
| SRP008496 | MOCS3 | 27304 | RNAseq | -0.4154 | 0.1309 | |
| SRP064894 | MOCS3 | 27304 | RNAseq | 0.3124 | 0.0335 | |
| SRP133303 | MOCS3 | 27304 | RNAseq | 0.2184 | 0.0741 | |
| SRP159526 | MOCS3 | 27304 | RNAseq | 0.1653 | 0.5393 | |
| SRP193095 | MOCS3 | 27304 | RNAseq | 0.1481 | 0.0879 | |
| SRP219564 | MOCS3 | 27304 | RNAseq | 0.4923 | 0.1366 | |
| TCGA | MOCS3 | 27304 | RNAseq | 0.1350 | 0.0417 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MOCS3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOCS3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOCS3 | 27304 | 16 | 2 | 12 | |
| GSE20123 | MOCS3 | 27304 | 16 | 2 | 12 | |
| GSE43470 | MOCS3 | 27304 | 13 | 0 | 30 | |
| GSE46452 | MOCS3 | 27304 | 29 | 0 | 30 | |
| GSE47630 | MOCS3 | 27304 | 24 | 1 | 15 | |
| GSE54993 | MOCS3 | 27304 | 0 | 17 | 53 | |
| GSE54994 | MOCS3 | 27304 | 27 | 0 | 26 | |
| GSE60625 | MOCS3 | 27304 | 0 | 0 | 11 | |
| GSE74703 | MOCS3 | 27304 | 11 | 0 | 25 | |
| GSE74704 | MOCS3 | 27304 | 12 | 0 | 8 | |
| TCGA | MOCS3 | 27304 | 46 | 3 | 47 |
Total number of gains: 194; Total number of losses: 25; Total Number of normals: 269.
Somatic mutations of MOCS3:
Generating mutation plots.
Highly correlated genes for MOCS3:
Showing top 20/288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOCS3 | SH3BP2 | 0.760289 | 3 | 0 | 3 |
| MOCS3 | CYP1A2 | 0.725051 | 3 | 0 | 3 |
| MOCS3 | MS4A5 | 0.694941 | 3 | 0 | 3 |
| MOCS3 | ABCD2 | 0.690061 | 3 | 0 | 3 |
| MOCS3 | RARG | 0.686356 | 3 | 0 | 3 |
| MOCS3 | CENPBD1 | 0.684502 | 3 | 0 | 3 |
| MOCS3 | PIGM | 0.674878 | 3 | 0 | 3 |
| MOCS3 | KDM5C | 0.67082 | 4 | 0 | 4 |
| MOCS3 | MXD3 | 0.669987 | 4 | 0 | 4 |
| MOCS3 | TRMT2B | 0.669475 | 3 | 0 | 3 |
| MOCS3 | CBL | 0.667912 | 5 | 0 | 5 |
| MOCS3 | TRIM26 | 0.658278 | 4 | 0 | 4 |
| MOCS3 | GNG3 | 0.657902 | 4 | 0 | 3 |
| MOCS3 | NAPA | 0.652749 | 3 | 0 | 3 |
| MOCS3 | PLCB2 | 0.652538 | 3 | 0 | 3 |
| MOCS3 | ARHGAP19 | 0.649937 | 3 | 0 | 3 |
| MOCS3 | C12orf73 | 0.645495 | 3 | 0 | 3 |
| MOCS3 | DDX41 | 0.645355 | 3 | 0 | 3 |
| MOCS3 | TPSG1 | 0.643875 | 4 | 0 | 3 |
| MOCS3 | EFTUD2 | 0.643489 | 4 | 0 | 4 |
For details and further investigation, click here
