| Full name: heparan sulfate-glucosamine 3-sulfotransferase 2 | Alias Symbol: 3OST2 | ||
| Type: protein-coding gene | Cytoband: 16p12.2 | ||
| Entrez ID: 9956 | HGNC ID: HGNC:5195 | Ensembl Gene: ENSG00000122254 | OMIM ID: 604056 |
| Drug and gene relationship at DGIdb | |||
Expression of HS3ST2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HS3ST2 | 9956 | 219697_at | -0.0983 | 0.8201 | |
| GSE20347 | HS3ST2 | 9956 | 219697_at | 0.0712 | 0.4522 | |
| GSE23400 | HS3ST2 | 9956 | 219697_at | -0.0644 | 0.1487 | |
| GSE26886 | HS3ST2 | 9956 | 219697_at | 0.1257 | 0.3061 | |
| GSE29001 | HS3ST2 | 9956 | 219697_at | -0.0612 | 0.7504 | |
| GSE38129 | HS3ST2 | 9956 | 219697_at | -0.1464 | 0.1488 | |
| GSE45670 | HS3ST2 | 9956 | 219697_at | -0.2359 | 0.1352 | |
| GSE53622 | HS3ST2 | 9956 | 50774 | 0.7738 | 0.0021 | |
| GSE53624 | HS3ST2 | 9956 | 43267 | 0.6809 | 0.0076 | |
| GSE63941 | HS3ST2 | 9956 | 219697_at | -0.0410 | 0.8760 | |
| GSE77861 | HS3ST2 | 9956 | 219697_at | -0.0813 | 0.5906 | |
| SRP133303 | HS3ST2 | 9956 | RNAseq | 1.6042 | 0.0001 | |
| TCGA | HS3ST2 | 9956 | RNAseq | -0.5645 | 0.1823 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HS3ST2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HS3ST2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HS3ST2 | 9956 | 7 | 3 | 20 | |
| GSE20123 | HS3ST2 | 9956 | 6 | 2 | 22 | |
| GSE43470 | HS3ST2 | 9956 | 3 | 3 | 37 | |
| GSE46452 | HS3ST2 | 9956 | 38 | 1 | 20 | |
| GSE47630 | HS3ST2 | 9956 | 11 | 6 | 23 | |
| GSE54993 | HS3ST2 | 9956 | 3 | 5 | 62 | |
| GSE54994 | HS3ST2 | 9956 | 4 | 10 | 39 | |
| GSE60625 | HS3ST2 | 9956 | 4 | 0 | 7 | |
| GSE74703 | HS3ST2 | 9956 | 3 | 2 | 31 | |
| GSE74704 | HS3ST2 | 9956 | 3 | 1 | 16 | |
| TCGA | HS3ST2 | 9956 | 19 | 13 | 64 |
Total number of gains: 101; Total number of losses: 46; Total Number of normals: 341.
Somatic mutations of HS3ST2:
Generating mutation plots.
Highly correlated genes for HS3ST2:
Showing top 20/436 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HS3ST2 | PEAK1 | 0.692106 | 4 | 0 | 4 |
| HS3ST2 | RRH | 0.667552 | 3 | 0 | 3 |
| HS3ST2 | NXPE4 | 0.660208 | 4 | 0 | 4 |
| HS3ST2 | MS4A5 | 0.65734 | 4 | 0 | 3 |
| HS3ST2 | KIR3DL3 | 0.656896 | 4 | 0 | 4 |
| HS3ST2 | NPBWR2 | 0.655967 | 4 | 0 | 3 |
| HS3ST2 | ATN1 | 0.651431 | 3 | 0 | 3 |
| HS3ST2 | LGALS13 | 0.651031 | 5 | 0 | 5 |
| HS3ST2 | GAD2 | 0.648238 | 6 | 0 | 5 |
| HS3ST2 | SLC17A7 | 0.646279 | 6 | 0 | 6 |
| HS3ST2 | C8A | 0.644202 | 3 | 0 | 3 |
| HS3ST2 | IFNA17 | 0.643231 | 4 | 0 | 4 |
| HS3ST2 | C1orf105 | 0.640313 | 6 | 0 | 5 |
| HS3ST2 | AFF3 | 0.638829 | 3 | 0 | 3 |
| HS3ST2 | S100G | 0.638066 | 3 | 0 | 3 |
| HS3ST2 | NCR3 | 0.636808 | 3 | 0 | 3 |
| HS3ST2 | EPX | 0.636201 | 3 | 0 | 3 |
| HS3ST2 | SGK2 | 0.635927 | 5 | 0 | 5 |
| HS3ST2 | GDF9 | 0.634765 | 5 | 0 | 4 |
| HS3ST2 | CNGB3 | 0.633962 | 4 | 0 | 4 |
For details and further investigation, click here
