MUC17

 

Full name: mucin 17, cell surface associated Alias Symbol: 
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 140453 HGNC ID: HGNC:16800 Ensembl Gene: ENSG00000169876 OMIM ID: 608424
Drug and gene relationship at DGIdb

 

Expression of MUC17:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MUC17 140453 232407_at -0.1081 0.6609
GSE26886 MUC17 140453 232407_at -0.3607 0.0017
GSE45670 MUC17 140453 232407_at 0.0371 0.7888
GSE53622 MUC17 140453 97967 0.3671 0.0020
GSE53624 MUC17 140453 97967 0.4961 0.0032
GSE63941 MUC17 140453 232407_at -0.2006 0.2871
GSE77861 MUC17 140453 232407_at -0.2688 0.0354
GSE97050 MUC17 140453 A_24_P169507 -0.1163 0.6606
TCGA MUC17 140453 RNAseq -1.3873 0.0867

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MUC17 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of MUC17:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MUC17 140453 13 0 17
GSE20123 MUC17 140453 13 0 17
GSE43470 MUC17 140453 7 2 34
GSE46452 MUC17 140453 11 1 47
GSE47630 MUC17 140453 7 3 30
GSE54993 MUC17 140453 1 10 59
GSE54994 MUC17 140453 15 3 35
GSE60625 MUC17 140453 0 0 11
GSE74703 MUC17 140453 7 1 28
GSE74704 MUC17 140453 9 0 11
TCGA MUC17 140453 53 6 37

Total number of gains: 136; Total number of losses: 26; Total Number of normals: 326.  


 

Somatic mutations of MUC17:

 

Generating mutation plots.

 

Highly correlated genes for MUC17:

 

Showing top 20/130 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MUC17SULT2B10.76245303
MUC17SERPINB30.754275303
MUC17CLIC30.75364303
MUC17C1orf1670.74936303
MUC17DLK20.736644303
MUC17AMER20.733691303
MUC17IL22RA10.733668303
MUC17IQCF20.72475303
MUC17SH3PXD2A-AS10.714832303
MUC17INSL30.709667303
MUC17SPNS20.70193303
MUC17PSCA0.682982303
MUC17SPAG170.682365303
MUC17CYP4F220.677463303
MUC17ACADM0.676736303
MUC17FTHL170.664249403
MUC17CDHR50.664145303
MUC17GRTP1-AS10.661707303
MUC17C1orf2100.660666303
MUC17OPN1SW0.659987403

For details and further investigation, click here