| Full name: interleukin 22 receptor subunit alpha 1 | Alias Symbol: CRF2-9 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 58985 | HGNC ID: HGNC:13700 | Ensembl Gene: ENSG00000142677 | OMIM ID: 605457 |
| Drug and gene relationship at DGIdb | |||
IL22RA1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of IL22RA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL22RA1 | 58985 | 220056_at | -0.7680 | 0.4284 | |
| GSE20347 | IL22RA1 | 58985 | 220056_at | -0.8191 | 0.0000 | |
| GSE23400 | IL22RA1 | 58985 | 220056_at | -0.6548 | 0.0000 | |
| GSE26886 | IL22RA1 | 58985 | 220056_at | -1.5806 | 0.0000 | |
| GSE29001 | IL22RA1 | 58985 | 220056_at | -1.0303 | 0.0004 | |
| GSE38129 | IL22RA1 | 58985 | 220056_at | -0.6449 | 0.0019 | |
| GSE45670 | IL22RA1 | 58985 | 220056_at | 0.0196 | 0.9583 | |
| GSE63941 | IL22RA1 | 58985 | 220056_at | 0.6304 | 0.0636 | |
| GSE77861 | IL22RA1 | 58985 | 220056_at | -0.7618 | 0.0070 | |
| SRP007169 | IL22RA1 | 58985 | RNAseq | -0.6316 | 0.2776 | |
| SRP064894 | IL22RA1 | 58985 | RNAseq | -1.4217 | 0.0016 | |
| SRP133303 | IL22RA1 | 58985 | RNAseq | -1.0614 | 0.0010 | |
| SRP159526 | IL22RA1 | 58985 | RNAseq | -1.8578 | 0.0000 | |
| SRP193095 | IL22RA1 | 58985 | RNAseq | -1.4631 | 0.0000 | |
| SRP219564 | IL22RA1 | 58985 | RNAseq | -2.4091 | 0.0381 | |
| TCGA | IL22RA1 | 58985 | RNAseq | 0.3257 | 0.0788 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by IL22RA1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of IL22RA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL22RA1 | 58985 | 0 | 5 | 25 | |
| GSE20123 | IL22RA1 | 58985 | 0 | 4 | 26 | |
| GSE43470 | IL22RA1 | 58985 | 2 | 6 | 35 | |
| GSE46452 | IL22RA1 | 58985 | 5 | 1 | 53 | |
| GSE47630 | IL22RA1 | 58985 | 8 | 3 | 29 | |
| GSE54993 | IL22RA1 | 58985 | 2 | 1 | 67 | |
| GSE54994 | IL22RA1 | 58985 | 11 | 4 | 38 | |
| GSE60625 | IL22RA1 | 58985 | 0 | 0 | 11 | |
| GSE74703 | IL22RA1 | 58985 | 1 | 4 | 31 | |
| GSE74704 | IL22RA1 | 58985 | 0 | 0 | 20 | |
| TCGA | IL22RA1 | 58985 | 10 | 23 | 63 |
Total number of gains: 39; Total number of losses: 51; Total Number of normals: 398.
Somatic mutations of IL22RA1:
Generating mutation plots.
Highly correlated genes for IL22RA1:
Showing top 20/1268 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL22RA1 | INO80C | 0.847113 | 4 | 0 | 4 |
| IL22RA1 | GRPEL2 | 0.837827 | 4 | 0 | 4 |
| IL22RA1 | ATG9B | 0.78741 | 4 | 0 | 4 |
| IL22RA1 | MIR210HG | 0.783276 | 4 | 0 | 4 |
| IL22RA1 | TGM1 | 0.782519 | 9 | 0 | 9 |
| IL22RA1 | LYNX1 | 0.780919 | 4 | 0 | 4 |
| IL22RA1 | TMPRSS11E | 0.779186 | 8 | 0 | 8 |
| IL22RA1 | CYSRT1 | 0.778396 | 4 | 0 | 4 |
| IL22RA1 | SH3GL1 | 0.776171 | 8 | 0 | 8 |
| IL22RA1 | PRSS2 | 0.772814 | 9 | 0 | 8 |
| IL22RA1 | ANXA9 | 0.772496 | 8 | 0 | 8 |
| IL22RA1 | SAMD5 | 0.769953 | 3 | 0 | 3 |
| IL22RA1 | EPS8L2 | 0.769418 | 8 | 0 | 8 |
| IL22RA1 | SCNN1B | 0.768914 | 8 | 0 | 8 |
| IL22RA1 | GDPD3 | 0.766011 | 9 | 0 | 8 |
| IL22RA1 | CWH43 | 0.765193 | 8 | 0 | 7 |
| IL22RA1 | HOPX | 0.765164 | 8 | 0 | 8 |
| IL22RA1 | GFOD2 | 0.764717 | 8 | 0 | 8 |
| IL22RA1 | SLC13A4 | 0.764442 | 8 | 0 | 8 |
| IL22RA1 | RAB11A | 0.764432 | 8 | 0 | 8 |
For details and further investigation, click here
