MUC20

 

Full name: mucin 20, cell surface associated Alias Symbol: FLJ14408|KIAA1359
Type: protein-coding gene Cytoband: 3q29
Entrez ID: 200958 HGNC ID: HGNC:23282 Ensembl Gene: ENSG00000176945 OMIM ID: 610360
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of MUC20:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MUC20 200958 226622_at -1.4366 0.3947
GSE26886 MUC20 200958 226622_at -3.2281 0.0000
GSE45670 MUC20 200958 226622_at -0.7840 0.1132
GSE53622 MUC20 200958 26569 -1.9646 0.0000
GSE53624 MUC20 200958 26569 -2.3604 0.0000
GSE63941 MUC20 200958 226622_at 2.0524 0.3424
GSE77861 MUC20 200958 226622_at -2.3636 0.0042
GSE97050 MUC20 200958 A_33_P3226775 -0.2924 0.3739
SRP007169 MUC20 200958 RNAseq -3.2792 0.0004
SRP008496 MUC20 200958 RNAseq -3.8429 0.0000
SRP064894 MUC20 200958 RNAseq -2.2519 0.0001
SRP133303 MUC20 200958 RNAseq -0.9659 0.0699
SRP159526 MUC20 200958 RNAseq -1.7989 0.0052
SRP193095 MUC20 200958 RNAseq -1.3215 0.0011
SRP219564 MUC20 200958 RNAseq -2.2376 0.0118
TCGA MUC20 200958 RNAseq -0.0771 0.7769

Upregulated datasets: 0; Downregulated datasets: 10.  

 

Survival by MUC20 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MUC20:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MUC20 200958 22 0 8
GSE20123 MUC20 200958 22 0 8
GSE43470 MUC20 200958 21 0 22
GSE46452 MUC20 200958 19 1 39
GSE47630 MUC20 200958 27 2 11
GSE54993 MUC20 200958 1 22 47
GSE54994 MUC20 200958 41 0 12
GSE60625 MUC20 200958 0 6 5
GSE74703 MUC20 200958 19 0 17
GSE74704 MUC20 200958 14 0 6
TCGA MUC20 200958 77 0 19

Total number of gains: 263; Total number of losses: 31; Total Number of normals: 194.  

 

Somatic mutations of MUC20:

 

Generating mutation plots.

 

Highly correlated genes for MUC20:

 

Showing top 20/1469 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MUC20C5orf66-AS10.817057606
MUC20IKZF20.803755808
MUC20ELF30.798082808
MUC20VSIG10L0.796983505
MUC20TTC90.794429808
MUC20LIPH0.790232707
MUC20EMP10.789244606
MUC20ST6GALNAC10.781564908
MUC20SASH10.777535707
MUC20TP53INP20.770911606
MUC20ANXA110.770572808
MUC20USP540.770525707
MUC20SLC10A50.770233303
MUC20GLTP0.77022505
MUC20FAM3B0.768485706
MUC20MECOM0.766658808
MUC20PCBP1-AS10.766077303
MUC20KIAA1211L0.764141707
MUC20KLB0.762026606
MUC20RHCG0.762013505

For details and further investigation, click here