| Full name: family with sequence similarity 3 member B | Alias Symbol: D21M16SJHU19e|PRED44|2-21|ORF9|C21orf76|PANDER | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 54097 | HGNC ID: HGNC:1253 | Ensembl Gene: ENSG00000183844 | OMIM ID: 608617 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM3B | 54097 | 227194_at | -2.8169 | 0.1705 | |
| GSE26886 | FAM3B | 54097 | 227194_at | -4.0902 | 0.0000 | |
| GSE45670 | FAM3B | 54097 | 227194_at | -2.0318 | 0.0247 | |
| GSE53622 | FAM3B | 54097 | 59022 | -4.3084 | 0.0000 | |
| GSE53624 | FAM3B | 54097 | 59022 | -4.8517 | 0.0000 | |
| GSE63941 | FAM3B | 54097 | 227194_at | 0.3309 | 0.1478 | |
| GSE77861 | FAM3B | 54097 | 227194_at | -2.7096 | 0.0072 | |
| SRP007169 | FAM3B | 54097 | RNAseq | -5.9107 | 0.0000 | |
| SRP008496 | FAM3B | 54097 | RNAseq | -6.0097 | 0.0000 | |
| SRP064894 | FAM3B | 54097 | RNAseq | -4.3809 | 0.0000 | |
| SRP133303 | FAM3B | 54097 | RNAseq | -2.8525 | 0.0034 | |
| SRP159526 | FAM3B | 54097 | RNAseq | -3.0375 | 0.0057 | |
| SRP193095 | FAM3B | 54097 | RNAseq | -2.8910 | 0.0000 | |
| TCGA | FAM3B | 54097 | RNAseq | -1.7683 | 0.0031 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by FAM3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM3B | 54097 | 2 | 8 | 20 | |
| GSE20123 | FAM3B | 54097 | 2 | 8 | 20 | |
| GSE43470 | FAM3B | 54097 | 0 | 13 | 30 | |
| GSE46452 | FAM3B | 54097 | 1 | 21 | 37 | |
| GSE47630 | FAM3B | 54097 | 6 | 17 | 17 | |
| GSE54993 | FAM3B | 54097 | 8 | 1 | 61 | |
| GSE54994 | FAM3B | 54097 | 3 | 8 | 42 | |
| GSE60625 | FAM3B | 54097 | 0 | 0 | 11 | |
| GSE74703 | FAM3B | 54097 | 0 | 10 | 26 | |
| GSE74704 | FAM3B | 54097 | 1 | 4 | 15 | |
| TCGA | FAM3B | 54097 | 7 | 41 | 48 |
Total number of gains: 30; Total number of losses: 131; Total Number of normals: 327.
Somatic mutations of FAM3B:
Generating mutation plots.
Highly correlated genes for FAM3B:
Showing top 20/1438 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM3B | IKZF2 | 0.882779 | 6 | 0 | 6 |
| FAM3B | SASH1 | 0.862049 | 6 | 0 | 6 |
| FAM3B | CTTNBP2 | 0.859118 | 6 | 0 | 6 |
| FAM3B | ABLIM1 | 0.849917 | 6 | 0 | 6 |
| FAM3B | FAM214A | 0.838752 | 6 | 0 | 6 |
| FAM3B | GALNT12 | 0.838414 | 6 | 0 | 6 |
| FAM3B | KRT78 | 0.834126 | 6 | 0 | 6 |
| FAM3B | KLB | 0.833298 | 6 | 0 | 6 |
| FAM3B | PPL | 0.832254 | 6 | 0 | 6 |
| FAM3B | MGST2 | 0.831176 | 6 | 0 | 6 |
| FAM3B | CAPN14 | 0.830324 | 6 | 0 | 6 |
| FAM3B | UBL3 | 0.830073 | 6 | 0 | 6 |
| FAM3B | PRSS27 | 0.829798 | 6 | 0 | 6 |
| FAM3B | CLCA4 | 0.827626 | 6 | 0 | 6 |
| FAM3B | LMO7 | 0.827448 | 6 | 0 | 6 |
| FAM3B | SH3BGRL2 | 0.826193 | 7 | 0 | 7 |
| FAM3B | SLC12A6 | 0.824692 | 3 | 0 | 3 |
| FAM3B | CRNN | 0.822291 | 6 | 0 | 6 |
| FAM3B | SNORA68 | 0.820541 | 4 | 0 | 4 |
| FAM3B | LPIN1 | 0.819575 | 5 | 0 | 5 |
For details and further investigation, click here
