| Full name: lipase H | Alias Symbol: mPA-PLA1|PLA1B|mPA-PLA1alpha|LPDLR | ||
| Type: protein-coding gene | Cytoband: 3q27.2 | ||
| Entrez ID: 200879 | HGNC ID: HGNC:18483 | Ensembl Gene: ENSG00000163898 | OMIM ID: 607365 |
| Drug and gene relationship at DGIdb | |||
Expression of LIPH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIPH | 200879 | 235871_at | -1.2872 | 0.3109 | |
| GSE26886 | LIPH | 200879 | 235871_at | -3.3402 | 0.0000 | |
| GSE45670 | LIPH | 200879 | 235871_at | -0.5973 | 0.1086 | |
| GSE53622 | LIPH | 200879 | 120913 | -2.2986 | 0.0000 | |
| GSE53624 | LIPH | 200879 | 120913 | -2.5536 | 0.0000 | |
| GSE63941 | LIPH | 200879 | 235871_at | 1.6494 | 0.1008 | |
| GSE77861 | LIPH | 200879 | 235871_at | -0.5721 | 0.0472 | |
| GSE97050 | LIPH | 200879 | A_23_P84219 | 0.4387 | 0.6361 | |
| SRP007169 | LIPH | 200879 | RNAseq | -1.7155 | 0.0235 | |
| SRP008496 | LIPH | 200879 | RNAseq | -2.7568 | 0.0000 | |
| SRP064894 | LIPH | 200879 | RNAseq | -2.5705 | 0.0000 | |
| SRP133303 | LIPH | 200879 | RNAseq | -0.7523 | 0.0867 | |
| SRP159526 | LIPH | 200879 | RNAseq | -1.9786 | 0.0085 | |
| SRP193095 | LIPH | 200879 | RNAseq | -1.5101 | 0.0000 | |
| SRP219564 | LIPH | 200879 | RNAseq | -2.6286 | 0.0036 | |
| TCGA | LIPH | 200879 | RNAseq | -1.0554 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by LIPH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIPH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIPH | 200879 | 25 | 0 | 5 | |
| GSE20123 | LIPH | 200879 | 25 | 0 | 5 | |
| GSE43470 | LIPH | 200879 | 23 | 0 | 20 | |
| GSE46452 | LIPH | 200879 | 19 | 1 | 39 | |
| GSE47630 | LIPH | 200879 | 27 | 2 | 11 | |
| GSE54993 | LIPH | 200879 | 1 | 19 | 50 | |
| GSE54994 | LIPH | 200879 | 40 | 0 | 13 | |
| GSE60625 | LIPH | 200879 | 0 | 6 | 5 | |
| GSE74703 | LIPH | 200879 | 20 | 0 | 16 | |
| GSE74704 | LIPH | 200879 | 17 | 0 | 3 | |
| TCGA | LIPH | 200879 | 77 | 0 | 19 |
Total number of gains: 274; Total number of losses: 28; Total Number of normals: 186.
Somatic mutations of LIPH:
Generating mutation plots.
Highly correlated genes for LIPH:
Showing top 20/1214 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIPH | LMO7 | 0.830022 | 7 | 0 | 7 |
| LIPH | CEACAM5 | 0.820356 | 8 | 0 | 8 |
| LIPH | CEACAM7 | 0.81187 | 7 | 0 | 7 |
| LIPH | FUT3 | 0.809334 | 8 | 0 | 8 |
| LIPH | TMEM154 | 0.809281 | 7 | 0 | 7 |
| LIPH | EPS8L1 | 0.808416 | 8 | 0 | 8 |
| LIPH | ATP13A4 | 0.806308 | 7 | 0 | 7 |
| LIPH | TPRG1 | 0.797286 | 6 | 0 | 6 |
| LIPH | SDCBP2 | 0.795817 | 3 | 0 | 3 |
| LIPH | CHP1 | 0.792264 | 6 | 0 | 6 |
| LIPH | PLEKHM1 | 0.790675 | 6 | 0 | 6 |
| LIPH | MUC20 | 0.790232 | 7 | 0 | 7 |
| LIPH | GCNT3 | 0.78719 | 8 | 0 | 7 |
| LIPH | CAPN14 | 0.786211 | 6 | 0 | 6 |
| LIPH | CEACAM3 | 0.784804 | 4 | 0 | 4 |
| LIPH | EVPL | 0.783927 | 8 | 0 | 8 |
| LIPH | SCEL | 0.783883 | 8 | 0 | 8 |
| LIPH | CEACAM1 | 0.783324 | 7 | 0 | 7 |
| LIPH | PAX9 | 0.781947 | 8 | 0 | 7 |
| LIPH | CAPN5 | 0.781633 | 6 | 0 | 6 |
For details and further investigation, click here
