| Full name: epithelial membrane protein 1 | Alias Symbol: TMP|CL-20 | ||
| Type: protein-coding gene | Cytoband: 12p13.1 | ||
| Entrez ID: 2012 | HGNC ID: HGNC:3333 | Ensembl Gene: ENSG00000134531 | OMIM ID: 602333 |
| Drug and gene relationship at DGIdb | |||
Expression of EMP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMP1 | 2012 | 201324_at | -1.8521 | 0.0326 | |
| GSE20347 | EMP1 | 2012 | 201324_at | -2.4387 | 0.0000 | |
| GSE23400 | EMP1 | 2012 | 201325_s_at | -2.9736 | 0.0000 | |
| GSE26886 | EMP1 | 2012 | 201324_at | -2.5926 | 0.0000 | |
| GSE29001 | EMP1 | 2012 | 201324_at | -2.2798 | 0.0000 | |
| GSE38129 | EMP1 | 2012 | 201324_at | -2.0108 | 0.0000 | |
| GSE45670 | EMP1 | 2012 | 201324_at | -0.7710 | 0.0107 | |
| GSE53622 | EMP1 | 2012 | 98864 | -3.4066 | 0.0000 | |
| GSE53624 | EMP1 | 2012 | 98864 | -3.8512 | 0.0000 | |
| GSE63941 | EMP1 | 2012 | 201324_at | -2.4336 | 0.1464 | |
| GSE77861 | EMP1 | 2012 | 201324_at | -1.4969 | 0.0081 | |
| GSE97050 | EMP1 | 2012 | A_23_P76488 | -2.1581 | 0.1057 | |
| SRP007169 | EMP1 | 2012 | RNAseq | -5.2694 | 0.0000 | |
| SRP008496 | EMP1 | 2012 | RNAseq | -4.6883 | 0.0000 | |
| SRP064894 | EMP1 | 2012 | RNAseq | -4.9481 | 0.0000 | |
| SRP133303 | EMP1 | 2012 | RNAseq | -4.1816 | 0.0000 | |
| SRP159526 | EMP1 | 2012 | RNAseq | -4.9960 | 0.0000 | |
| SRP193095 | EMP1 | 2012 | RNAseq | -4.4679 | 0.0000 | |
| SRP219564 | EMP1 | 2012 | RNAseq | -4.2996 | 0.0000 | |
| TCGA | EMP1 | 2012 | RNAseq | -0.1573 | 0.1634 |
Upregulated datasets: 0; Downregulated datasets: 16.
Survival by EMP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EMP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMP1 | 2012 | 6 | 2 | 22 | |
| GSE20123 | EMP1 | 2012 | 6 | 2 | 22 | |
| GSE43470 | EMP1 | 2012 | 9 | 4 | 30 | |
| GSE46452 | EMP1 | 2012 | 10 | 1 | 48 | |
| GSE47630 | EMP1 | 2012 | 13 | 2 | 25 | |
| GSE54993 | EMP1 | 2012 | 2 | 9 | 59 | |
| GSE54994 | EMP1 | 2012 | 10 | 2 | 41 | |
| GSE60625 | EMP1 | 2012 | 0 | 1 | 10 | |
| GSE74703 | EMP1 | 2012 | 9 | 3 | 24 | |
| GSE74704 | EMP1 | 2012 | 4 | 1 | 15 | |
| TCGA | EMP1 | 2012 | 39 | 7 | 50 |
Total number of gains: 108; Total number of losses: 34; Total Number of normals: 346.
Somatic mutations of EMP1:
Generating mutation plots.
Highly correlated genes for EMP1:
Showing top 20/1496 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMP1 | CYSRT1 | 0.914273 | 6 | 0 | 6 |
| EMP1 | ECM1 | 0.907472 | 11 | 0 | 11 |
| EMP1 | SCEL | 0.897597 | 12 | 0 | 12 |
| EMP1 | FAM214A | 0.889478 | 6 | 0 | 6 |
| EMP1 | PPL | 0.886537 | 12 | 0 | 12 |
| EMP1 | CRCT1 | 0.883894 | 11 | 0 | 11 |
| EMP1 | RHCG | 0.880057 | 11 | 0 | 11 |
| EMP1 | TMPRSS11B | 0.876706 | 8 | 0 | 8 |
| EMP1 | SPINK5 | 0.876437 | 12 | 0 | 11 |
| EMP1 | IL1RN | 0.876346 | 11 | 0 | 11 |
| EMP1 | CNFN | 0.873725 | 7 | 0 | 7 |
| EMP1 | SMIM5 | 0.872186 | 6 | 0 | 6 |
| EMP1 | TMPRSS11E | 0.871475 | 11 | 0 | 11 |
| EMP1 | VSIG10L | 0.868729 | 7 | 0 | 7 |
| EMP1 | CRNN | 0.867819 | 12 | 0 | 12 |
| EMP1 | SPINK7 | 0.867497 | 8 | 0 | 8 |
| EMP1 | EPS8L1 | 0.866778 | 11 | 0 | 11 |
| EMP1 | KRT4 | 0.865801 | 12 | 0 | 12 |
| EMP1 | SLURP1 | 0.865111 | 12 | 0 | 11 |
| EMP1 | ENDOU | 0.861934 | 11 | 0 | 11 |
For details and further investigation, click here
