| Full name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 | Alias Symbol: ST6GalNAcI | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 55808 | HGNC ID: HGNC:23614 | Ensembl Gene: ENSG00000070526 | OMIM ID: 610138 |
| Drug and gene relationship at DGIdb | |||
Expression of ST6GALNAC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ST6GALNAC1 | 55808 | 227725_at | -2.3020 | 0.1889 | |
| GSE26886 | ST6GALNAC1 | 55808 | 227725_at | -3.6035 | 0.0000 | |
| GSE45670 | ST6GALNAC1 | 55808 | 227725_at | -1.4157 | 0.0133 | |
| GSE53622 | ST6GALNAC1 | 55808 | 121084 | -2.8268 | 0.0000 | |
| GSE53624 | ST6GALNAC1 | 55808 | 121084 | -3.5562 | 0.0000 | |
| GSE63941 | ST6GALNAC1 | 55808 | 227725_at | 2.5311 | 0.1466 | |
| GSE77861 | ST6GALNAC1 | 55808 | 227725_at | -2.1439 | 0.0011 | |
| GSE97050 | ST6GALNAC1 | 55808 | A_23_P54968 | -0.4419 | 0.2103 | |
| SRP007169 | ST6GALNAC1 | 55808 | RNAseq | -2.7582 | 0.0784 | |
| SRP008496 | ST6GALNAC1 | 55808 | RNAseq | -3.0408 | 0.0018 | |
| SRP064894 | ST6GALNAC1 | 55808 | RNAseq | -2.6484 | 0.0000 | |
| SRP133303 | ST6GALNAC1 | 55808 | RNAseq | -1.9559 | 0.0002 | |
| SRP159526 | ST6GALNAC1 | 55808 | RNAseq | -1.7652 | 0.0491 | |
| SRP193095 | ST6GALNAC1 | 55808 | RNAseq | -2.0111 | 0.0000 | |
| SRP219564 | ST6GALNAC1 | 55808 | RNAseq | -2.8145 | 0.0068 | |
| TCGA | ST6GALNAC1 | 55808 | RNAseq | -1.4630 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by ST6GALNAC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ST6GALNAC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ST6GALNAC1 | 55808 | 7 | 2 | 21 | |
| GSE20123 | ST6GALNAC1 | 55808 | 7 | 2 | 21 | |
| GSE43470 | ST6GALNAC1 | 55808 | 4 | 3 | 36 | |
| GSE46452 | ST6GALNAC1 | 55808 | 33 | 1 | 25 | |
| GSE47630 | ST6GALNAC1 | 55808 | 8 | 1 | 31 | |
| GSE54993 | ST6GALNAC1 | 55808 | 2 | 5 | 63 | |
| GSE54994 | ST6GALNAC1 | 55808 | 10 | 4 | 39 | |
| GSE60625 | ST6GALNAC1 | 55808 | 6 | 0 | 5 | |
| GSE74703 | ST6GALNAC1 | 55808 | 4 | 1 | 31 | |
| GSE74704 | ST6GALNAC1 | 55808 | 5 | 1 | 14 | |
| TCGA | ST6GALNAC1 | 55808 | 31 | 10 | 55 |
Total number of gains: 117; Total number of losses: 30; Total Number of normals: 341.
Somatic mutations of ST6GALNAC1:
Generating mutation plots.
Highly correlated genes for ST6GALNAC1:
Showing top 20/1495 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ST6GALNAC1 | IKZF2 | 0.845492 | 8 | 0 | 8 |
| ST6GALNAC1 | C5orf66-AS1 | 0.843747 | 6 | 0 | 6 |
| ST6GALNAC1 | SPAG17 | 0.838765 | 5 | 0 | 5 |
| ST6GALNAC1 | SMIM5 | 0.837697 | 6 | 0 | 6 |
| ST6GALNAC1 | CHP1 | 0.832462 | 6 | 0 | 6 |
| ST6GALNAC1 | GBP6 | 0.826081 | 4 | 0 | 4 |
| ST6GALNAC1 | SIM2 | 0.822774 | 7 | 0 | 7 |
| ST6GALNAC1 | SNORA68 | 0.817544 | 4 | 0 | 4 |
| ST6GALNAC1 | ACPP | 0.814978 | 7 | 0 | 7 |
| ST6GALNAC1 | PCBP1-AS1 | 0.811056 | 3 | 0 | 3 |
| ST6GALNAC1 | CAPN5 | 0.81045 | 7 | 0 | 7 |
| ST6GALNAC1 | CLIC3 | 0.810374 | 5 | 0 | 5 |
| ST6GALNAC1 | KALRN | 0.80974 | 6 | 0 | 6 |
| ST6GALNAC1 | UPK3B | 0.808252 | 3 | 0 | 3 |
| ST6GALNAC1 | LMO7 | 0.805397 | 7 | 0 | 7 |
| ST6GALNAC1 | FAM3D | 0.804623 | 9 | 0 | 8 |
| ST6GALNAC1 | UBL3 | 0.800967 | 7 | 0 | 7 |
| ST6GALNAC1 | EPHX2 | 0.799944 | 6 | 0 | 6 |
| ST6GALNAC1 | SLC35C1 | 0.799659 | 6 | 0 | 6 |
| ST6GALNAC1 | FAM3B | 0.799336 | 7 | 0 | 6 |
For details and further investigation, click here
