| Full name: MYCL proto-oncogene, bHLH transcription factor | Alias Symbol: LMYC|bHLHe38 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 4610 | HGNC ID: HGNC:7555 | Ensembl Gene: ENSG00000116990 | OMIM ID: 164850 |
Expression of MYCL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYCL | 4610 | 214058_at | 0.1262 | 0.9245 | |
| GSE20347 | MYCL | 4610 | 214058_at | -0.7890 | 0.0092 | |
| GSE23400 | MYCL | 4610 | 214058_at | -0.1335 | 0.4346 | |
| GSE26886 | MYCL | 4610 | 214058_at | -1.5569 | 0.0007 | |
| GSE29001 | MYCL | 4610 | 214058_at | -0.2862 | 0.6593 | |
| GSE38129 | MYCL | 4610 | 214058_at | -0.1526 | 0.6972 | |
| GSE45670 | MYCL | 4610 | 214058_at | -0.0289 | 0.9534 | |
| GSE53622 | MYCL | 4610 | 4519 | -0.9235 | 0.0004 | |
| GSE53624 | MYCL | 4610 | 4519 | -0.7154 | 0.0000 | |
| GSE63941 | MYCL | 4610 | 214058_at | 2.1811 | 0.0153 | |
| GSE77861 | MYCL | 4610 | 214058_at | -0.2746 | 0.6348 | |
| SRP007169 | MYCL | 4610 | RNAseq | -1.4158 | 0.0003 | |
| SRP008496 | MYCL | 4610 | RNAseq | -1.6271 | 0.0000 | |
| SRP064894 | MYCL | 4610 | RNAseq | -0.6634 | 0.0736 | |
| SRP133303 | MYCL | 4610 | RNAseq | -0.8559 | 0.0013 | |
| SRP159526 | MYCL | 4610 | RNAseq | 1.2266 | 0.1408 | |
| SRP193095 | MYCL | 4610 | RNAseq | -0.8791 | 0.0049 | |
| SRP219564 | MYCL | 4610 | RNAseq | -0.3067 | 0.6852 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by MYCL expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MYCL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYCL | 4610 | 3 | 4 | 23 | |
| GSE20123 | MYCL | 4610 | 2 | 3 | 25 | |
| GSE43470 | MYCL | 4610 | 7 | 2 | 34 | |
| GSE46452 | MYCL | 4610 | 4 | 1 | 54 | |
| GSE47630 | MYCL | 4610 | 9 | 2 | 29 | |
| GSE54993 | MYCL | 4610 | 0 | 1 | 69 | |
| GSE54994 | MYCL | 4610 | 13 | 2 | 38 | |
| GSE60625 | MYCL | 4610 | 0 | 0 | 11 | |
| GSE74703 | MYCL | 4610 | 6 | 1 | 29 | |
| GSE74704 | MYCL | 4610 | 1 | 0 | 19 | |
| TCGA | MYCL | 4610 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of MYCL:
Generating mutation plots.
Highly correlated genes for MYCL:
Showing top 20/496 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYCL | NDUFS3 | 0.742703 | 3 | 0 | 3 |
| MYCL | SLC39A11 | 0.71863 | 3 | 0 | 3 |
| MYCL | KIAA1522 | 0.710623 | 3 | 0 | 3 |
| MYCL | SYTL5 | 0.692723 | 3 | 0 | 3 |
| MYCL | PANK1 | 0.686778 | 5 | 0 | 4 |
| MYCL | SLC25A41 | 0.684264 | 3 | 0 | 3 |
| MYCL | SLC25A3 | 0.68406 | 4 | 0 | 4 |
| MYCL | ARF3 | 0.676074 | 4 | 0 | 3 |
| MYCL | ITGB7 | 0.666383 | 3 | 0 | 3 |
| MYCL | TIMMDC1 | 0.658314 | 4 | 0 | 4 |
| MYCL | ATP6V0D1 | 0.657787 | 3 | 0 | 3 |
| MYCL | ARMCX6 | 0.657234 | 3 | 0 | 3 |
| MYCL | CNOT11 | 0.651694 | 4 | 0 | 4 |
| MYCL | RAB3D | 0.648239 | 7 | 0 | 6 |
| MYCL | CHCHD1 | 0.646236 | 4 | 0 | 3 |
| MYCL | GPR157 | 0.64526 | 4 | 0 | 3 |
| MYCL | MFSD5 | 0.643123 | 7 | 0 | 6 |
| MYCL | OVOL2 | 0.641187 | 5 | 0 | 5 |
| MYCL | SNX16 | 0.637319 | 3 | 0 | 3 |
| MYCL | COQ9 | 0.634136 | 3 | 0 | 3 |
For details and further investigation, click here
