| Full name: CCR4-NOT transcription complex subunit 11 | Alias Symbol: C40 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 55571 | HGNC ID: HGNC:25217 | Ensembl Gene: ENSG00000158435 | OMIM ID: |
Screen Evidence:
| |||
Expression of CNOT11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNOT11 | 55571 | 224695_at | 0.2695 | 0.6073 | |
| GSE26886 | CNOT11 | 55571 | 224695_at | -0.9432 | 0.0000 | |
| GSE45670 | CNOT11 | 55571 | 224695_at | 0.2549 | 0.0283 | |
| GSE53622 | CNOT11 | 55571 | 63533 | -0.3102 | 0.0000 | |
| GSE53624 | CNOT11 | 55571 | 63533 | -0.0968 | 0.1116 | |
| GSE63941 | CNOT11 | 55571 | 224695_at | -0.0551 | 0.8792 | |
| GSE77861 | CNOT11 | 55571 | 224695_at | 0.1274 | 0.4942 | |
| SRP007169 | CNOT11 | 55571 | RNAseq | -0.4311 | 0.1801 | |
| SRP008496 | CNOT11 | 55571 | RNAseq | -0.5100 | 0.0325 | |
| SRP064894 | CNOT11 | 55571 | RNAseq | -0.2753 | 0.0806 | |
| SRP133303 | CNOT11 | 55571 | RNAseq | 0.1701 | 0.2459 | |
| SRP159526 | CNOT11 | 55571 | RNAseq | -0.0296 | 0.9283 | |
| SRP193095 | CNOT11 | 55571 | RNAseq | -0.2383 | 0.0126 | |
| SRP219564 | CNOT11 | 55571 | RNAseq | -0.6470 | 0.0178 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CNOT11 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CNOT11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNOT11 | 55571 | 5 | 2 | 23 | |
| GSE20123 | CNOT11 | 55571 | 5 | 2 | 23 | |
| GSE43470 | CNOT11 | 55571 | 5 | 1 | 37 | |
| GSE46452 | CNOT11 | 55571 | 1 | 4 | 54 | |
| GSE47630 | CNOT11 | 55571 | 7 | 0 | 33 | |
| GSE54993 | CNOT11 | 55571 | 0 | 6 | 64 | |
| GSE54994 | CNOT11 | 55571 | 11 | 0 | 42 | |
| GSE60625 | CNOT11 | 55571 | 0 | 3 | 8 | |
| GSE74703 | CNOT11 | 55571 | 5 | 1 | 30 | |
| GSE74704 | CNOT11 | 55571 | 3 | 1 | 16 | |
| TCGA | CNOT11 | 55571 | 35 | 5 | 56 |
Total number of gains: 77; Total number of losses: 25; Total Number of normals: 386.
Somatic mutations of CNOT11:
Generating mutation plots.
Highly correlated genes for CNOT11:
Showing top 20/194 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNOT11 | PRKCH | 0.774326 | 3 | 0 | 3 |
| CNOT11 | P4HB | 0.741908 | 3 | 0 | 3 |
| CNOT11 | OXLD1 | 0.731597 | 3 | 0 | 3 |
| CNOT11 | MFSD5 | 0.725996 | 3 | 0 | 3 |
| CNOT11 | TRMT10A | 0.707744 | 3 | 0 | 3 |
| CNOT11 | DCAF12 | 0.703832 | 3 | 0 | 3 |
| CNOT11 | METAP1 | 0.701463 | 3 | 0 | 3 |
| CNOT11 | MAPK13 | 0.697991 | 3 | 0 | 3 |
| CNOT11 | YIPF1 | 0.695435 | 4 | 0 | 4 |
| CNOT11 | TSPAN6 | 0.689461 | 3 | 0 | 3 |
| CNOT11 | TWF1 | 0.688512 | 3 | 0 | 3 |
| CNOT11 | TFIP11 | 0.688354 | 3 | 0 | 3 |
| CNOT11 | DAPP1 | 0.687459 | 3 | 0 | 3 |
| CNOT11 | PEX11B | 0.686315 | 3 | 0 | 3 |
| CNOT11 | MREG | 0.684462 | 3 | 0 | 3 |
| CNOT11 | CSK | 0.681864 | 3 | 0 | 3 |
| CNOT11 | PPP2R1B | 0.681139 | 3 | 0 | 3 |
| CNOT11 | PTPN3 | 0.676876 | 3 | 0 | 3 |
| CNOT11 | TMPRSS4 | 0.67553 | 5 | 0 | 5 |
| CNOT11 | GRHL3 | 0.674344 | 3 | 0 | 3 |
For details and further investigation, click here
