| Full name: sorting nexin 16 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q21.13 | ||
| Entrez ID: 64089 | HGNC ID: HGNC:14980 | Ensembl Gene: ENSG00000104497 | OMIM ID: 614903 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX16 | 64089 | 229618_at | -0.0169 | 0.9822 | |
| GSE20347 | SNX16 | 64089 | 219793_at | -1.8307 | 0.0000 | |
| GSE23400 | SNX16 | 64089 | 219793_at | -0.6164 | 0.0000 | |
| GSE26886 | SNX16 | 64089 | 229618_at | -1.5015 | 0.0000 | |
| GSE29001 | SNX16 | 64089 | 219793_at | -1.5112 | 0.0074 | |
| GSE38129 | SNX16 | 64089 | 219793_at | -1.3031 | 0.0000 | |
| GSE45670 | SNX16 | 64089 | 229618_at | -0.0125 | 0.9527 | |
| GSE53622 | SNX16 | 64089 | 3675 | -0.4180 | 0.0000 | |
| GSE53624 | SNX16 | 64089 | 3675 | -0.5641 | 0.0000 | |
| GSE63941 | SNX16 | 64089 | 229618_at | -0.4189 | 0.4961 | |
| GSE77861 | SNX16 | 64089 | 229618_at | -0.7106 | 0.0314 | |
| GSE97050 | SNX16 | 64089 | A_24_P320880 | 0.1533 | 0.5526 | |
| SRP007169 | SNX16 | 64089 | RNAseq | -2.0379 | 0.0000 | |
| SRP008496 | SNX16 | 64089 | RNAseq | -1.8026 | 0.0000 | |
| SRP064894 | SNX16 | 64089 | RNAseq | -0.7441 | 0.0188 | |
| SRP133303 | SNX16 | 64089 | RNAseq | -0.8349 | 0.0000 | |
| SRP159526 | SNX16 | 64089 | RNAseq | -1.1563 | 0.0000 | |
| SRP193095 | SNX16 | 64089 | RNAseq | -1.6040 | 0.0000 | |
| SRP219564 | SNX16 | 64089 | RNAseq | -1.3339 | 0.0027 | |
| TCGA | SNX16 | 64089 | RNAseq | -0.0426 | 0.5580 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by SNX16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX16 | 64089 | 14 | 1 | 15 | |
| GSE20123 | SNX16 | 64089 | 16 | 1 | 13 | |
| GSE43470 | SNX16 | 64089 | 18 | 1 | 24 | |
| GSE46452 | SNX16 | 64089 | 21 | 0 | 38 | |
| GSE47630 | SNX16 | 64089 | 23 | 0 | 17 | |
| GSE54993 | SNX16 | 64089 | 0 | 19 | 51 | |
| GSE54994 | SNX16 | 64089 | 30 | 0 | 23 | |
| GSE60625 | SNX16 | 64089 | 0 | 4 | 7 | |
| GSE74703 | SNX16 | 64089 | 15 | 1 | 20 | |
| GSE74704 | SNX16 | 64089 | 10 | 0 | 10 | |
| TCGA | SNX16 | 64089 | 51 | 2 | 43 |
Total number of gains: 198; Total number of losses: 29; Total Number of normals: 261.
Somatic mutations of SNX16:
Generating mutation plots.
Highly correlated genes for SNX16:
Showing top 20/369 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX16 | RTKN2 | 0.770493 | 3 | 0 | 3 |
| SNX16 | CLIC3 | 0.709063 | 6 | 0 | 6 |
| SNX16 | GFOD2 | 0.706676 | 6 | 0 | 6 |
| SNX16 | NICN1 | 0.705625 | 3 | 0 | 3 |
| SNX16 | ALOX12 | 0.687308 | 6 | 0 | 6 |
| SNX16 | TMOD3 | 0.681161 | 8 | 0 | 6 |
| SNX16 | CPEB3 | 0.674944 | 8 | 0 | 6 |
| SNX16 | RBM47 | 0.674888 | 8 | 0 | 7 |
| SNX16 | PRSS2 | 0.673393 | 7 | 0 | 7 |
| SNX16 | EMC3 | 0.671351 | 8 | 0 | 7 |
| SNX16 | RGS12 | 0.667522 | 6 | 0 | 6 |
| SNX16 | SASH1 | 0.663098 | 8 | 0 | 7 |
| SNX16 | SULT2B1 | 0.662191 | 7 | 0 | 7 |
| SNX16 | DIO2 | 0.661141 | 7 | 0 | 7 |
| SNX16 | SLC37A1 | 0.660768 | 8 | 0 | 7 |
| SNX16 | PRDM1 | 0.660687 | 7 | 0 | 6 |
| SNX16 | FUT3 | 0.659683 | 7 | 0 | 6 |
| SNX16 | ADIRF | 0.659385 | 5 | 0 | 5 |
| SNX16 | CWH43 | 0.658123 | 8 | 0 | 6 |
| SNX16 | TICAM1 | 0.657949 | 5 | 0 | 5 |
For details and further investigation, click here
