| Full name: major facilitator superfamily domain containing 5 | Alias Symbol: MGC11308|HsMOT2 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 84975 | HGNC ID: HGNC:28156 | Ensembl Gene: ENSG00000182544 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD5 | 84975 | 212861_at | -0.8114 | 0.3827 | |
| GSE20347 | MFSD5 | 84975 | 212861_at | -1.3899 | 0.0000 | |
| GSE23400 | MFSD5 | 84975 | 212861_at | -0.8076 | 0.0000 | |
| GSE26886 | MFSD5 | 84975 | 212861_at | -2.5386 | 0.0000 | |
| GSE29001 | MFSD5 | 84975 | 212861_at | -1.3855 | 0.0000 | |
| GSE38129 | MFSD5 | 84975 | 212861_at | -0.7477 | 0.0009 | |
| GSE45670 | MFSD5 | 84975 | 212861_at | -0.4633 | 0.0176 | |
| GSE53622 | MFSD5 | 84975 | 66492 | -0.8874 | 0.0000 | |
| GSE53624 | MFSD5 | 84975 | 66492 | -1.2162 | 0.0000 | |
| GSE63941 | MFSD5 | 84975 | 212861_at | -1.0845 | 0.0102 | |
| GSE77861 | MFSD5 | 84975 | 212861_at | -0.6466 | 0.0296 | |
| GSE97050 | MFSD5 | 84975 | A_23_P72853 | -0.3456 | 0.4766 | |
| SRP007169 | MFSD5 | 84975 | RNAseq | -2.4952 | 0.0000 | |
| SRP008496 | MFSD5 | 84975 | RNAseq | -2.2746 | 0.0000 | |
| SRP064894 | MFSD5 | 84975 | RNAseq | -1.1020 | 0.0000 | |
| SRP133303 | MFSD5 | 84975 | RNAseq | -0.9305 | 0.0000 | |
| SRP159526 | MFSD5 | 84975 | RNAseq | -1.2973 | 0.0000 | |
| SRP193095 | MFSD5 | 84975 | RNAseq | -1.0997 | 0.0000 | |
| SRP219564 | MFSD5 | 84975 | RNAseq | -0.9952 | 0.0552 | |
| TCGA | MFSD5 | 84975 | RNAseq | 0.0623 | 0.3223 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by MFSD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFSD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD5 | 84975 | 7 | 1 | 22 | |
| GSE20123 | MFSD5 | 84975 | 7 | 1 | 22 | |
| GSE43470 | MFSD5 | 84975 | 3 | 0 | 40 | |
| GSE46452 | MFSD5 | 84975 | 7 | 1 | 51 | |
| GSE47630 | MFSD5 | 84975 | 10 | 2 | 28 | |
| GSE54993 | MFSD5 | 84975 | 0 | 5 | 65 | |
| GSE54994 | MFSD5 | 84975 | 4 | 1 | 48 | |
| GSE60625 | MFSD5 | 84975 | 0 | 0 | 11 | |
| GSE74703 | MFSD5 | 84975 | 3 | 0 | 33 | |
| GSE74704 | MFSD5 | 84975 | 5 | 1 | 14 | |
| TCGA | MFSD5 | 84975 | 14 | 11 | 71 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of MFSD5:
Generating mutation plots.
Highly correlated genes for MFSD5:
Showing top 20/1757 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD5 | GDPD3 | 0.845496 | 10 | 0 | 10 |
| MFSD5 | ACPP | 0.836221 | 10 | 0 | 10 |
| MFSD5 | RAB11A | 0.820352 | 11 | 0 | 11 |
| MFSD5 | CRCT1 | 0.818209 | 10 | 0 | 10 |
| MFSD5 | SMAGP | 0.818083 | 11 | 0 | 10 |
| MFSD5 | SH3GL1 | 0.816204 | 11 | 0 | 11 |
| MFSD5 | ENDOU | 0.812598 | 11 | 0 | 11 |
| MFSD5 | ORMDL2 | 0.812174 | 9 | 0 | 9 |
| MFSD5 | CNFN | 0.810097 | 6 | 0 | 6 |
| MFSD5 | IL1RN | 0.809389 | 10 | 0 | 10 |
| MFSD5 | TTC9 | 0.809367 | 11 | 0 | 11 |
| MFSD5 | SCNN1B | 0.80727 | 10 | 0 | 10 |
| MFSD5 | ASCC2 | 0.805897 | 11 | 0 | 11 |
| MFSD5 | ULK3 | 0.804881 | 7 | 0 | 7 |
| MFSD5 | SLC16A6 | 0.804784 | 11 | 0 | 11 |
| MFSD5 | TOM1 | 0.804529 | 12 | 0 | 11 |
| MFSD5 | OSTF1 | 0.802721 | 11 | 0 | 11 |
| MFSD5 | ABLIM1 | 0.802664 | 11 | 0 | 11 |
| MFSD5 | SNORA68 | 0.802508 | 4 | 0 | 4 |
| MFSD5 | SPNS2 | 0.801969 | 5 | 0 | 5 |
For details and further investigation, click here
