| Full name: translocase of inner mitochondrial membrane domain containing 1 | Alias Symbol: FLJ22597 | ||
| Type: protein-coding gene | Cytoband: 3q13.33 | ||
| Entrez ID: 51300 | HGNC ID: HGNC:1321 | Ensembl Gene: ENSG00000113845 | OMIM ID: 615534 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TIMMDC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIMMDC1 | 51300 | 223004_s_at | 0.4471 | 0.2105 | |
| GSE26886 | TIMMDC1 | 51300 | 223004_s_at | -0.2585 | 0.1734 | |
| GSE45670 | TIMMDC1 | 51300 | 223004_s_at | 0.5209 | 0.0003 | |
| GSE53622 | TIMMDC1 | 51300 | 29447 | -0.7236 | 0.0000 | |
| GSE53624 | TIMMDC1 | 51300 | 29447 | -0.1083 | 0.0502 | |
| GSE63941 | TIMMDC1 | 51300 | 223004_s_at | 0.0704 | 0.8463 | |
| GSE77861 | TIMMDC1 | 51300 | 223004_s_at | 0.2201 | 0.5854 | |
| GSE97050 | TIMMDC1 | 51300 | A_23_P18413 | -0.1094 | 0.7642 | |
| SRP007169 | TIMMDC1 | 51300 | RNAseq | -0.0400 | 0.9009 | |
| SRP008496 | TIMMDC1 | 51300 | RNAseq | 0.2031 | 0.3455 | |
| SRP064894 | TIMMDC1 | 51300 | RNAseq | 0.5816 | 0.0014 | |
| SRP133303 | TIMMDC1 | 51300 | RNAseq | 0.4724 | 0.0110 | |
| SRP159526 | TIMMDC1 | 51300 | RNAseq | 0.5036 | 0.0123 | |
| SRP193095 | TIMMDC1 | 51300 | RNAseq | 0.1689 | 0.1568 | |
| SRP219564 | TIMMDC1 | 51300 | RNAseq | -0.0563 | 0.8711 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TIMMDC1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TIMMDC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TIMMDC1 | 51300 | 17 | 0 | 13 | |
| GSE20123 | TIMMDC1 | 51300 | 17 | 0 | 13 | |
| GSE43470 | TIMMDC1 | 51300 | 21 | 1 | 21 | |
| GSE46452 | TIMMDC1 | 51300 | 14 | 5 | 40 | |
| GSE47630 | TIMMDC1 | 51300 | 16 | 5 | 19 | |
| GSE54993 | TIMMDC1 | 51300 | 2 | 6 | 62 | |
| GSE54994 | TIMMDC1 | 51300 | 30 | 4 | 19 | |
| GSE60625 | TIMMDC1 | 51300 | 0 | 6 | 5 | |
| GSE74703 | TIMMDC1 | 51300 | 17 | 1 | 18 | |
| GSE74704 | TIMMDC1 | 51300 | 13 | 0 | 7 | |
| TCGA | TIMMDC1 | 51300 | 53 | 7 | 36 |
Total number of gains: 200; Total number of losses: 35; Total Number of normals: 253.
Somatic mutations of TIMMDC1:
Generating mutation plots.
Highly correlated genes for TIMMDC1:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIMMDC1 | NAA50 | 0.744811 | 5 | 0 | 5 |
| TIMMDC1 | ABCF3 | 0.740938 | 3 | 0 | 3 |
| TIMMDC1 | ALG1 | 0.73888 | 3 | 0 | 3 |
| TIMMDC1 | UMPS | 0.725124 | 4 | 0 | 3 |
| TIMMDC1 | FBXO45 | 0.720261 | 3 | 0 | 3 |
| TIMMDC1 | TMEM39A | 0.716477 | 4 | 0 | 4 |
| TIMMDC1 | FOXRED1 | 0.709424 | 3 | 0 | 3 |
| TIMMDC1 | NOC4L | 0.698938 | 3 | 0 | 3 |
| TIMMDC1 | ARHGAP11A | 0.695998 | 3 | 0 | 3 |
| TIMMDC1 | PHF12 | 0.684649 | 4 | 0 | 3 |
| TIMMDC1 | OAZ1 | 0.671912 | 3 | 0 | 3 |
| TIMMDC1 | PDCD10 | 0.67122 | 3 | 0 | 3 |
| TIMMDC1 | RPUSD1 | 0.669221 | 4 | 0 | 3 |
| TIMMDC1 | ZBTB17 | 0.666923 | 3 | 0 | 3 |
| TIMMDC1 | CDC20 | 0.659155 | 3 | 0 | 3 |
| TIMMDC1 | MYCL | 0.658314 | 4 | 0 | 4 |
| TIMMDC1 | CDK2AP1 | 0.653858 | 3 | 0 | 3 |
| TIMMDC1 | CDCA5 | 0.652852 | 3 | 0 | 3 |
| TIMMDC1 | TRMT10C | 0.652526 | 4 | 0 | 3 |
| TIMMDC1 | TTI1 | 0.651039 | 4 | 0 | 4 |
For details and further investigation, click here
