| Full name: G protein-coupled receptor 157 | Alias Symbol: FLJ12132 | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 80045 | HGNC ID: HGNC:23687 | Ensembl Gene: ENSG00000180758 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GPR157:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR157 | 80045 | 227970_at | -0.5089 | 0.6802 | |
| GSE20347 | GPR157 | 80045 | 220901_at | -0.1989 | 0.1604 | |
| GSE23400 | GPR157 | 80045 | 220901_at | -0.1898 | 0.0017 | |
| GSE26886 | GPR157 | 80045 | 227970_at | -2.2922 | 0.0000 | |
| GSE29001 | GPR157 | 80045 | 220901_at | -0.2324 | 0.3481 | |
| GSE38129 | GPR157 | 80045 | 220901_at | -0.1638 | 0.3702 | |
| GSE45670 | GPR157 | 80045 | 227970_at | -0.4693 | 0.1127 | |
| GSE53622 | GPR157 | 80045 | 40964 | -1.3448 | 0.0000 | |
| GSE53624 | GPR157 | 80045 | 40964 | -1.4148 | 0.0000 | |
| GSE63941 | GPR157 | 80045 | 227970_at | 0.6744 | 0.3176 | |
| GSE77861 | GPR157 | 80045 | 227970_at | -1.0721 | 0.0009 | |
| GSE97050 | GPR157 | 80045 | A_33_P3280700 | 0.1429 | 0.6898 | |
| SRP007169 | GPR157 | 80045 | RNAseq | -3.1035 | 0.0000 | |
| SRP008496 | GPR157 | 80045 | RNAseq | -2.9698 | 0.0000 | |
| SRP064894 | GPR157 | 80045 | RNAseq | -1.6715 | 0.0000 | |
| SRP133303 | GPR157 | 80045 | RNAseq | -1.4241 | 0.0000 | |
| SRP159526 | GPR157 | 80045 | RNAseq | -1.8908 | 0.0001 | |
| SRP193095 | GPR157 | 80045 | RNAseq | -1.1071 | 0.0000 | |
| SRP219564 | GPR157 | 80045 | RNAseq | -1.2541 | 0.1095 | |
| TCGA | GPR157 | 80045 | RNAseq | 0.3105 | 0.0166 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by GPR157 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR157:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR157 | 80045 | 1 | 5 | 24 | |
| GSE20123 | GPR157 | 80045 | 1 | 3 | 26 | |
| GSE43470 | GPR157 | 80045 | 6 | 5 | 32 | |
| GSE46452 | GPR157 | 80045 | 7 | 1 | 51 | |
| GSE47630 | GPR157 | 80045 | 8 | 4 | 28 | |
| GSE54993 | GPR157 | 80045 | 3 | 2 | 65 | |
| GSE54994 | GPR157 | 80045 | 12 | 4 | 37 | |
| GSE60625 | GPR157 | 80045 | 0 | 0 | 11 | |
| GSE74703 | GPR157 | 80045 | 5 | 3 | 28 | |
| GSE74704 | GPR157 | 80045 | 1 | 0 | 19 | |
| TCGA | GPR157 | 80045 | 11 | 24 | 61 |
Total number of gains: 55; Total number of losses: 51; Total Number of normals: 382.
Somatic mutations of GPR157:
Generating mutation plots.
Highly correlated genes for GPR157:
Showing top 20/1334 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR157 | S100A16 | 0.821118 | 7 | 0 | 7 |
| GPR157 | NCCRP1 | 0.820856 | 3 | 0 | 3 |
| GPR157 | GRHL3 | 0.8171 | 7 | 0 | 7 |
| GPR157 | C6orf132 | 0.807038 | 7 | 0 | 7 |
| GPR157 | SPRR2F | 0.805359 | 3 | 0 | 3 |
| GPR157 | TMEM79 | 0.803181 | 7 | 0 | 7 |
| GPR157 | SPRR2D | 0.797125 | 3 | 0 | 3 |
| GPR157 | SPRR2E | 0.789025 | 3 | 0 | 3 |
| GPR157 | PRSS27 | 0.782799 | 7 | 0 | 7 |
| GPR157 | TMEM154 | 0.779564 | 7 | 0 | 7 |
| GPR157 | TMPRSS11A | 0.775594 | 3 | 0 | 3 |
| GPR157 | SPRR2A | 0.775052 | 3 | 0 | 3 |
| GPR157 | MPZL3 | 0.769898 | 6 | 0 | 6 |
| GPR157 | CAPN14 | 0.767772 | 6 | 0 | 6 |
| GPR157 | BLOC1S2 | 0.767089 | 3 | 0 | 3 |
| GPR157 | GRHL1 | 0.766958 | 7 | 0 | 7 |
| GPR157 | RHBDL2 | 0.764097 | 7 | 0 | 7 |
| GPR157 | ZFAND2B | 0.763946 | 6 | 0 | 6 |
| GPR157 | GSKIP | 0.761347 | 6 | 0 | 6 |
| GPR157 | BTBD11 | 0.76098 | 7 | 0 | 7 |
For details and further investigation, click here
