KIAA1522

 

Full name: KIAA1522 Alias Symbol: 
Type: protein-coding gene Cytoband: 1p35.1
Entrez ID: 57648 HGNC ID: HGNC:29301 Ensembl Gene: ENSG00000162522 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of KIAA1522:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KIAA1522 57648 224746_at 0.5336 0.2955
GSE26886 KIAA1522 57648 224746_at -0.1014 0.7226
GSE45670 KIAA1522 57648 224746_at 0.2812 0.1004
GSE53622 KIAA1522 57648 84621 -0.1441 0.2339
GSE53624 KIAA1522 57648 84621 0.0293 0.6864
GSE63941 KIAA1522 57648 224746_at 2.0241 0.0000
GSE77861 KIAA1522 57648 224746_at 0.1018 0.6709
GSE97050 KIAA1522 57648 A_23_P410965 0.2743 0.3026
SRP007169 KIAA1522 57648 RNAseq 0.7132 0.0775
SRP008496 KIAA1522 57648 RNAseq 0.1031 0.7452
SRP064894 KIAA1522 57648 RNAseq -0.1009 0.6706
SRP133303 KIAA1522 57648 RNAseq 0.0044 0.9870
SRP159526 KIAA1522 57648 RNAseq -0.0761 0.7330
SRP193095 KIAA1522 57648 RNAseq -0.2686 0.0432
SRP219564 KIAA1522 57648 RNAseq -0.7554 0.1711
TCGA KIAA1522 57648 RNAseq -0.0340 0.5773

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by KIAA1522 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KIAA1522:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KIAA1522 57648 2 5 23
GSE20123 KIAA1522 57648 2 4 24
GSE43470 KIAA1522 57648 5 6 32
GSE46452 KIAA1522 57648 5 1 53
GSE47630 KIAA1522 57648 8 3 29
GSE54993 KIAA1522 57648 1 1 68
GSE54994 KIAA1522 57648 11 2 40
GSE60625 KIAA1522 57648 0 0 11
GSE74703 KIAA1522 57648 4 3 29
GSE74704 KIAA1522 57648 1 0 19
TCGA KIAA1522 57648 12 18 66

Total number of gains: 51; Total number of losses: 43; Total Number of normals: 394.  

 

Somatic mutations of KIAA1522:

 

Generating mutation plots.

 

Highly correlated genes for KIAA1522:

 

Showing top 20/747 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KIAA1522TMPO0.844641303
KIAA1522EPN30.830648303
KIAA1522E2F80.792826404
KIAA1522NCAPD20.782191303
KIAA1522GINS10.77575303
KIAA1522NT5DC20.775359303
KIAA1522DNAJC90.771657303
KIAA1522C1orf1120.770235303
KIAA1522MAP3K90.759453303
KIAA1522PAQR40.756223303
KIAA1522EYA30.753017303
KIAA1522TMCO60.74607404
KIAA1522BUB30.74315303
KIAA1522SLC39A110.742666303
KIAA1522TOPBP10.740484303
KIAA1522RECQL50.731876303
KIAA1522POM1210.729553303
KIAA1522UBE2T0.72916303
KIAA1522MFSD90.728693303
KIAA1522E2F20.721794504

For details and further investigation, click here