| Full name: solute carrier family 25 member 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q23.1 | ||
| Entrez ID: 5250 | HGNC ID: HGNC:10989 | Ensembl Gene: ENSG00000075415 | OMIM ID: 600370 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of SLC25A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A3 | 5250 | 200030_s_at | -0.0732 | 0.8352 | |
| GSE20347 | SLC25A3 | 5250 | 200030_s_at | -0.2821 | 0.0204 | |
| GSE23400 | SLC25A3 | 5250 | 200030_s_at | 0.0021 | 0.9680 | |
| GSE26886 | SLC25A3 | 5250 | 200030_s_at | -0.5606 | 0.0002 | |
| GSE29001 | SLC25A3 | 5250 | 200030_s_at | -0.2061 | 0.3792 | |
| GSE38129 | SLC25A3 | 5250 | 200030_s_at | -0.1537 | 0.1241 | |
| GSE45670 | SLC25A3 | 5250 | 200030_s_at | -0.1861 | 0.0311 | |
| GSE53622 | SLC25A3 | 5250 | 143550 | -0.4105 | 0.0000 | |
| GSE53624 | SLC25A3 | 5250 | 143550 | -0.0906 | 0.1341 | |
| GSE63941 | SLC25A3 | 5250 | 200030_s_at | 0.3359 | 0.0946 | |
| GSE77861 | SLC25A3 | 5250 | 200030_s_at | 0.0013 | 0.9959 | |
| GSE97050 | SLC25A3 | 5250 | A_23_P25204 | -0.3357 | 0.2192 | |
| SRP007169 | SLC25A3 | 5250 | RNAseq | -0.6070 | 0.0647 | |
| SRP008496 | SLC25A3 | 5250 | RNAseq | -0.6841 | 0.0002 | |
| SRP064894 | SLC25A3 | 5250 | RNAseq | -0.2146 | 0.2568 | |
| SRP133303 | SLC25A3 | 5250 | RNAseq | -0.2327 | 0.0139 | |
| SRP159526 | SLC25A3 | 5250 | RNAseq | -0.3590 | 0.1860 | |
| SRP193095 | SLC25A3 | 5250 | RNAseq | -0.5819 | 0.0000 | |
| SRP219564 | SLC25A3 | 5250 | RNAseq | -0.5353 | 0.0424 | |
| TCGA | SLC25A3 | 5250 | RNAseq | -0.1151 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC25A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A3 | 5250 | 2 | 3 | 25 | |
| GSE20123 | SLC25A3 | 5250 | 2 | 3 | 25 | |
| GSE43470 | SLC25A3 | 5250 | 2 | 0 | 41 | |
| GSE46452 | SLC25A3 | 5250 | 9 | 1 | 49 | |
| GSE47630 | SLC25A3 | 5250 | 9 | 2 | 29 | |
| GSE54993 | SLC25A3 | 5250 | 0 | 5 | 65 | |
| GSE54994 | SLC25A3 | 5250 | 4 | 2 | 47 | |
| GSE60625 | SLC25A3 | 5250 | 0 | 0 | 11 | |
| GSE74703 | SLC25A3 | 5250 | 2 | 0 | 34 | |
| GSE74704 | SLC25A3 | 5250 | 1 | 2 | 17 | |
| TCGA | SLC25A3 | 5250 | 17 | 9 | 70 |
Total number of gains: 48; Total number of losses: 27; Total Number of normals: 413.
Somatic mutations of SLC25A3:
Generating mutation plots.
Highly correlated genes for SLC25A3:
Showing top 20/816 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A3 | CDC26 | 0.819226 | 3 | 0 | 3 |
| SLC25A3 | FEM1A | 0.783027 | 3 | 0 | 3 |
| SLC25A3 | UBE4B | 0.779123 | 4 | 0 | 4 |
| SLC25A3 | GAB1 | 0.768275 | 3 | 0 | 3 |
| SLC25A3 | UBE3C | 0.76462 | 3 | 0 | 3 |
| SLC25A3 | MKRN1 | 0.762164 | 4 | 0 | 3 |
| SLC25A3 | AP3M1 | 0.75995 | 3 | 0 | 3 |
| SLC25A3 | PRPF38A | 0.749667 | 4 | 0 | 4 |
| SLC25A3 | ZNF41 | 0.747953 | 3 | 0 | 3 |
| SLC25A3 | PRADC1 | 0.744715 | 5 | 0 | 5 |
| SLC25A3 | SOS1 | 0.743734 | 4 | 0 | 3 |
| SLC25A3 | POLR2L | 0.739555 | 4 | 0 | 4 |
| SLC25A3 | TET2 | 0.725092 | 3 | 0 | 3 |
| SLC25A3 | BLOC1S2 | 0.723443 | 3 | 0 | 3 |
| SLC25A3 | USP25 | 0.721575 | 3 | 0 | 3 |
| SLC25A3 | CIB1 | 0.719589 | 3 | 0 | 3 |
| SLC25A3 | FBXO8 | 0.719558 | 4 | 0 | 4 |
| SLC25A3 | FMO3 | 0.718328 | 3 | 0 | 3 |
| SLC25A3 | VCPIP1 | 0.71382 | 3 | 0 | 3 |
| SLC25A3 | SNAPIN | 0.713141 | 4 | 0 | 4 |
For details and further investigation, click here
