| Full name: FRY microtubule binding protein | Alias Symbol: bA37E23.1|13CDNA73|CG003 | ||
| Type: protein-coding gene | Cytoband: 13q13.1 | ||
| Entrez ID: 10129 | HGNC ID: HGNC:20367 | Ensembl Gene: ENSG00000073910 | OMIM ID: 614818 |
| Drug and gene relationship at DGIdb | |||
Expression of FRY:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FRY | 10129 | 204072_s_at | -1.3551 | 0.2698 | |
| GSE20347 | FRY | 10129 | 204072_s_at | -0.4562 | 0.1382 | |
| GSE23400 | FRY | 10129 | 204072_s_at | -0.4097 | 0.0337 | |
| GSE26886 | FRY | 10129 | 204072_s_at | 0.1812 | 0.8152 | |
| GSE29001 | FRY | 10129 | 204072_s_at | -0.7990 | 0.0580 | |
| GSE38129 | FRY | 10129 | 204072_s_at | -0.9242 | 0.0471 | |
| GSE45670 | FRY | 10129 | 204072_s_at | -1.7479 | 0.0001 | |
| GSE53622 | FRY | 10129 | 66673 | -0.4046 | 0.0037 | |
| GSE53624 | FRY | 10129 | 3099 | -0.6492 | 0.0000 | |
| GSE63941 | FRY | 10129 | 204072_s_at | -4.1386 | 0.0031 | |
| GSE77861 | FRY | 10129 | 1555904_at | -0.0735 | 0.5048 | |
| GSE97050 | FRY | 10129 | A_33_P3223488 | -0.3240 | 0.3083 | |
| SRP007169 | FRY | 10129 | RNAseq | 0.6671 | 0.2317 | |
| SRP008496 | FRY | 10129 | RNAseq | 0.0638 | 0.8619 | |
| SRP064894 | FRY | 10129 | RNAseq | 0.2695 | 0.4110 | |
| SRP133303 | FRY | 10129 | RNAseq | 0.0472 | 0.8670 | |
| SRP159526 | FRY | 10129 | RNAseq | 0.2183 | 0.6126 | |
| SRP193095 | FRY | 10129 | RNAseq | -0.2299 | 0.4344 | |
| SRP219564 | FRY | 10129 | RNAseq | -0.2044 | 0.8102 | |
| TCGA | FRY | 10129 | RNAseq | -0.7409 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by FRY expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FRY:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FRY | 10129 | 1 | 15 | 14 | |
| GSE20123 | FRY | 10129 | 1 | 14 | 15 | |
| GSE43470 | FRY | 10129 | 2 | 13 | 28 | |
| GSE46452 | FRY | 10129 | 0 | 33 | 26 | |
| GSE47630 | FRY | 10129 | 2 | 27 | 11 | |
| GSE54993 | FRY | 10129 | 12 | 2 | 56 | |
| GSE54994 | FRY | 10129 | 2 | 15 | 36 | |
| GSE60625 | FRY | 10129 | 0 | 3 | 8 | |
| GSE74703 | FRY | 10129 | 2 | 10 | 24 | |
| GSE74704 | FRY | 10129 | 0 | 12 | 8 | |
| TCGA | FRY | 10129 | 7 | 38 | 51 |
Total number of gains: 29; Total number of losses: 182; Total Number of normals: 277.
Somatic mutations of FRY:
Generating mutation plots.
Highly correlated genes for FRY:
Showing top 20/1156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FRY | FNIP2 | 0.831228 | 3 | 0 | 3 |
| FRY | MYADM | 0.820021 | 3 | 0 | 3 |
| FRY | TSHZ3 | 0.804053 | 3 | 0 | 3 |
| FRY | C11orf96 | 0.786194 | 4 | 0 | 4 |
| FRY | ZNF407 | 0.781725 | 3 | 0 | 3 |
| FRY | C1orf198 | 0.771088 | 3 | 0 | 3 |
| FRY | MEOX2 | 0.761981 | 8 | 0 | 8 |
| FRY | EMCN | 0.761946 | 5 | 0 | 5 |
| FRY | TMEM170B | 0.760804 | 6 | 0 | 6 |
| FRY | PREX2 | 0.755618 | 4 | 0 | 4 |
| FRY | MYEF2 | 0.755154 | 4 | 0 | 4 |
| FRY | EBF3 | 0.75354 | 4 | 0 | 4 |
| FRY | KCNT2 | 0.749693 | 6 | 0 | 6 |
| FRY | ACO1 | 0.748922 | 5 | 0 | 5 |
| FRY | MRVI1 | 0.748833 | 6 | 0 | 6 |
| FRY | ARMC9 | 0.741515 | 4 | 0 | 4 |
| FRY | LMO3 | 0.740104 | 8 | 0 | 8 |
| FRY | C1QTNF7 | 0.739124 | 5 | 0 | 5 |
| FRY | LRRN4CL | 0.737706 | 6 | 0 | 6 |
| FRY | FNBP1 | 0.73579 | 9 | 0 | 8 |
For details and further investigation, click here
