| Full name: myosin IIIA | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10p12.1 | ||
| Entrez ID: 53904 | HGNC ID: HGNC:7601 | Ensembl Gene: ENSG00000095777 | OMIM ID: 606808 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO3A | 53904 | 221400_at | -0.1017 | 0.6370 | |
| GSE20347 | MYO3A | 53904 | 221400_at | -0.0186 | 0.8319 | |
| GSE23400 | MYO3A | 53904 | 221400_at | -0.0706 | 0.0605 | |
| GSE26886 | MYO3A | 53904 | 221400_at | 0.1482 | 0.2961 | |
| GSE29001 | MYO3A | 53904 | 221400_at | -0.0881 | 0.4140 | |
| GSE38129 | MYO3A | 53904 | 221400_at | 0.0037 | 0.9665 | |
| GSE45670 | MYO3A | 53904 | 221400_at | 0.1945 | 0.0723 | |
| GSE53622 | MYO3A | 53904 | 14253 | -0.0404 | 0.9078 | |
| GSE53624 | MYO3A | 53904 | 14253 | -0.0939 | 0.6403 | |
| GSE63941 | MYO3A | 53904 | 221400_at | 0.1908 | 0.7337 | |
| GSE77861 | MYO3A | 53904 | 244364_at | -0.0842 | 0.4415 | |
| SRP064894 | MYO3A | 53904 | RNAseq | 0.7095 | 0.3048 | |
| SRP133303 | MYO3A | 53904 | RNAseq | 0.3580 | 0.4169 | |
| SRP159526 | MYO3A | 53904 | RNAseq | -0.2670 | 0.8014 | |
| TCGA | MYO3A | 53904 | RNAseq | 1.1749 | 0.0552 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYO3A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO3A | 53904 | 4 | 7 | 19 | |
| GSE20123 | MYO3A | 53904 | 4 | 6 | 20 | |
| GSE43470 | MYO3A | 53904 | 3 | 4 | 36 | |
| GSE46452 | MYO3A | 53904 | 1 | 14 | 44 | |
| GSE47630 | MYO3A | 53904 | 5 | 15 | 20 | |
| GSE54993 | MYO3A | 53904 | 9 | 0 | 61 | |
| GSE54994 | MYO3A | 53904 | 3 | 10 | 40 | |
| GSE60625 | MYO3A | 53904 | 0 | 0 | 11 | |
| GSE74703 | MYO3A | 53904 | 2 | 2 | 32 | |
| GSE74704 | MYO3A | 53904 | 0 | 5 | 15 | |
| TCGA | MYO3A | 53904 | 18 | 24 | 54 |
Total number of gains: 49; Total number of losses: 87; Total Number of normals: 352.
Somatic mutations of MYO3A:
Generating mutation plots.
Highly correlated genes for MYO3A:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO3A | KCNK9 | 0.709035 | 3 | 0 | 3 |
| MYO3A | AMELY | 0.688802 | 3 | 0 | 3 |
| MYO3A | STAB2 | 0.679531 | 3 | 0 | 3 |
| MYO3A | IRS4 | 0.671001 | 3 | 0 | 3 |
| MYO3A | RALYL | 0.66379 | 3 | 0 | 3 |
| MYO3A | OR1D2 | 0.656939 | 4 | 0 | 4 |
| MYO3A | HRH4 | 0.650939 | 3 | 0 | 3 |
| MYO3A | CCDC7 | 0.648953 | 4 | 0 | 4 |
| MYO3A | GJB4 | 0.646763 | 3 | 0 | 3 |
| MYO3A | CDH10 | 0.644342 | 3 | 0 | 3 |
| MYO3A | LGALS14 | 0.642894 | 3 | 0 | 3 |
| MYO3A | RIT2 | 0.642548 | 3 | 0 | 3 |
| MYO3A | DNAI2 | 0.640578 | 6 | 0 | 6 |
| MYO3A | SPX | 0.640317 | 3 | 0 | 3 |
| MYO3A | SLC22A2 | 0.636454 | 3 | 0 | 3 |
| MYO3A | CTSE | 0.633818 | 3 | 0 | 3 |
| MYO3A | OR12D3 | 0.631935 | 3 | 0 | 3 |
| MYO3A | GYG2 | 0.629403 | 3 | 0 | 3 |
| MYO3A | KRT36 | 0.628403 | 4 | 0 | 3 |
| MYO3A | NOS1 | 0.626414 | 3 | 0 | 3 |
For details and further investigation, click here
