| Full name: keratin 36 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 8689 | HGNC ID: HGNC:6454 | Ensembl Gene: ENSG00000126337 | OMIM ID: 604540 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT36 | 8689 | 214576_at | -0.7146 | 0.1153 | |
| GSE20347 | KRT36 | 8689 | 214576_at | -0.2127 | 0.0021 | |
| GSE23400 | KRT36 | 8689 | 214576_at | -0.3599 | 0.0000 | |
| GSE26886 | KRT36 | 8689 | 214576_at | -0.1943 | 0.1091 | |
| GSE29001 | KRT36 | 8689 | 214576_at | -0.5049 | 0.0113 | |
| GSE38129 | KRT36 | 8689 | 214576_at | -0.2522 | 0.0001 | |
| GSE45670 | KRT36 | 8689 | 214576_at | 0.0699 | 0.6558 | |
| GSE53622 | KRT36 | 8689 | 71415 | -1.1328 | 0.0000 | |
| GSE53624 | KRT36 | 8689 | 71415 | -0.7500 | 0.0000 | |
| GSE63941 | KRT36 | 8689 | 214576_at | 0.0776 | 0.6874 | |
| GSE77861 | KRT36 | 8689 | 214576_at | -0.1837 | 0.2955 | |
| GSE97050 | KRT36 | 8689 | A_23_P55400 | -0.3749 | 0.3526 | |
| SRP133303 | KRT36 | 8689 | RNAseq | -4.7640 | 0.0000 | |
| TCGA | KRT36 | 8689 | RNAseq | 1.1448 | 0.2211 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KRT36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT36 | 8689 | 6 | 2 | 22 | |
| GSE20123 | KRT36 | 8689 | 6 | 2 | 22 | |
| GSE43470 | KRT36 | 8689 | 1 | 2 | 40 | |
| GSE46452 | KRT36 | 8689 | 34 | 0 | 25 | |
| GSE47630 | KRT36 | 8689 | 8 | 1 | 31 | |
| GSE54993 | KRT36 | 8689 | 3 | 4 | 63 | |
| GSE54994 | KRT36 | 8689 | 8 | 5 | 40 | |
| GSE60625 | KRT36 | 8689 | 4 | 0 | 7 | |
| GSE74703 | KRT36 | 8689 | 1 | 1 | 34 | |
| GSE74704 | KRT36 | 8689 | 4 | 1 | 15 | |
| TCGA | KRT36 | 8689 | 23 | 7 | 66 |
Total number of gains: 98; Total number of losses: 25; Total Number of normals: 365.
Somatic mutations of KRT36:
Generating mutation plots.
Highly correlated genes for KRT36:
Showing top 20/902 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT36 | MFSD2B | 0.728126 | 3 | 0 | 3 |
| KRT36 | LIM2 | 0.712263 | 3 | 0 | 3 |
| KRT36 | FAM171A2 | 0.706972 | 3 | 0 | 3 |
| KRT36 | RETN | 0.705373 | 3 | 0 | 3 |
| KRT36 | FOLH1 | 0.704579 | 4 | 0 | 3 |
| KRT36 | REG3A | 0.703641 | 4 | 0 | 3 |
| KRT36 | SYCE3 | 0.703547 | 3 | 0 | 3 |
| KRT36 | MECR | 0.697747 | 3 | 0 | 3 |
| KRT36 | BRSK1 | 0.686785 | 3 | 0 | 3 |
| KRT36 | NANOS2 | 0.674743 | 5 | 0 | 5 |
| KRT36 | MYL2 | 0.674733 | 3 | 0 | 3 |
| KRT36 | RAX | 0.674188 | 4 | 0 | 3 |
| KRT36 | FRMPD1 | 0.669219 | 4 | 0 | 4 |
| KRT36 | GALNT9 | 0.669147 | 6 | 0 | 5 |
| KRT36 | TRIM10 | 0.664182 | 4 | 0 | 4 |
| KRT36 | INHBC | 0.663086 | 3 | 0 | 3 |
| KRT36 | TMEM37 | 0.661812 | 3 | 0 | 3 |
| KRT36 | KCNC3 | 0.660153 | 5 | 0 | 4 |
| KRT36 | ADM2 | 0.659842 | 5 | 0 | 4 |
| KRT36 | FGFR4 | 0.659425 | 4 | 0 | 3 |
For details and further investigation, click here
