MS4A12

 

Full name: membrane spanning 4-domains A12 Alias Symbol: Ms4a10|FLJ20217
Type: protein-coding gene Cytoband: 11q12.2
Entrez ID: 54860 HGNC ID: HGNC:13370 Ensembl Gene: ENSG00000071203 OMIM ID: 606550
Drug and gene relationship at DGIdb

 

Expression of MS4A12:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MS4A12 54860 220834_at 0.0702 0.8072
GSE20347 MS4A12 54860 220834_at -0.0070 0.9243
GSE23400 MS4A12 54860 220834_at -0.0872 0.0173
GSE26886 MS4A12 54860 220834_at -0.0315 0.8278
GSE29001 MS4A12 54860 220834_at -0.1851 0.1952
GSE38129 MS4A12 54860 220834_at -0.0256 0.7125
GSE45670 MS4A12 54860 220834_at 0.0682 0.4363
GSE63941 MS4A12 54860 220834_at -0.0284 0.8493
GSE77861 MS4A12 54860 220834_at -0.0700 0.4056

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by MS4A12 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of MS4A12:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MS4A12 54860 2 5 23
GSE20123 MS4A12 54860 2 5 23
GSE43470 MS4A12 54860 2 5 36
GSE46452 MS4A12 54860 8 4 47
GSE47630 MS4A12 54860 3 8 29
GSE54993 MS4A12 54860 3 0 67
GSE54994 MS4A12 54860 5 5 43
GSE60625 MS4A12 54860 0 3 8
GSE74703 MS4A12 54860 2 3 31
GSE74704 MS4A12 54860 2 3 15
TCGA MS4A12 54860 15 10 71

Total number of gains: 44; Total number of losses: 51; Total Number of normals: 393.  


 

Somatic mutations of MS4A12:

 

Generating mutation plots.

 

Highly correlated genes for MS4A12:

 

Showing top 20/573 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MS4A12GJB40.710964505
MS4A12TRH0.698475505
MS4A12CYP19A10.692585505
MS4A12RALYL0.692462303
MS4A12PRL0.681191505
MS4A12TBX210.68116303
MS4A12UNC5C0.67702303
MS4A12GABRB20.675002404
MS4A12NXNL10.66954303
MS4A12SLC12A30.663846403
MS4A12PDE3B0.66155403
MS4A12IL1RAPL20.661481504
MS4A12MYH80.660347403
MS4A12MYT1L0.660032403
MS4A12C11orf160.659884404
MS4A12GBA30.65634303
MS4A12TNR0.654344404
MS4A12BPY20.653533504
MS4A12LHX30.653049605
MS4A12C20orf2030.652388303

For details and further investigation, click here