| Full name: chromosome 1 open reading frame 68 | Alias Symbol: LEP7|XP32 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 100129271 | HGNC ID: HGNC:29468 | Ensembl Gene: ENSG00000198854 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf68:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf68 | 100129271 | 217087_at | -0.0245 | 0.9517 | |
| GSE20347 | C1orf68 | 100129271 | 216701_at | -0.1761 | 0.0049 | |
| GSE23400 | C1orf68 | 100129271 | 217087_at | -0.1183 | 0.0043 | |
| GSE26886 | C1orf68 | 100129271 | 217087_at | 0.0961 | 0.4167 | |
| GSE29001 | C1orf68 | 100129271 | 217087_at | -0.1473 | 0.4069 | |
| GSE38129 | C1orf68 | 100129271 | 216701_at | -0.1869 | 0.0043 | |
| GSE45670 | C1orf68 | 100129271 | 217087_at | 0.0239 | 0.8883 | |
| GSE53622 | C1orf68 | 100129271 | 109330 | 0.4016 | 0.0005 | |
| GSE53624 | C1orf68 | 100129271 | 109330 | 0.7357 | 0.0000 | |
| GSE63941 | C1orf68 | 100129271 | 217087_at | -0.1146 | 0.5014 | |
| GSE77861 | C1orf68 | 100129271 | 217087_at | 0.0399 | 0.7393 | |
| GSE97050 | C1orf68 | 100129271 | A_33_P3285456 | -0.0703 | 0.7876 | |
| TCGA | C1orf68 | 100129271 | RNAseq | 4.8682 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by C1orf68 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf68:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf68 | 100129271 | 15 | 0 | 15 | |
| GSE20123 | C1orf68 | 100129271 | 15 | 0 | 15 | |
| GSE43470 | C1orf68 | 100129271 | 6 | 2 | 35 | |
| GSE46452 | C1orf68 | 100129271 | 3 | 1 | 55 | |
| GSE47630 | C1orf68 | 100129271 | 15 | 0 | 25 | |
| GSE54993 | C1orf68 | 100129271 | 0 | 4 | 66 | |
| GSE54994 | C1orf68 | 100129271 | 15 | 0 | 38 | |
| GSE60625 | C1orf68 | 100129271 | 0 | 0 | 11 | |
| GSE74703 | C1orf68 | 100129271 | 6 | 1 | 29 | |
| GSE74704 | C1orf68 | 100129271 | 7 | 0 | 13 | |
| TCGA | C1orf68 | 100129271 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of C1orf68:
Generating mutation plots.
Highly correlated genes for C1orf68:
Showing top 20/389 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf68 | CSF1 | 0.760941 | 3 | 0 | 3 |
| C1orf68 | NKAIN1 | 0.75475 | 3 | 0 | 3 |
| C1orf68 | SH2D3C | 0.740811 | 3 | 0 | 3 |
| C1orf68 | TCN2 | 0.737427 | 3 | 0 | 3 |
| C1orf68 | NEU3 | 0.736702 | 3 | 0 | 3 |
| C1orf68 | CBL | 0.730933 | 3 | 0 | 3 |
| C1orf68 | NMNAT2 | 0.726451 | 3 | 0 | 3 |
| C1orf68 | IFNA14 | 0.725038 | 3 | 0 | 3 |
| C1orf68 | OR1E1 | 0.721541 | 3 | 0 | 3 |
| C1orf68 | SERPIND1 | 0.716128 | 4 | 0 | 4 |
| C1orf68 | CNTF | 0.712553 | 3 | 0 | 3 |
| C1orf68 | LZTS1 | 0.703093 | 3 | 0 | 3 |
| C1orf68 | PRR34 | 0.69951 | 3 | 0 | 3 |
| C1orf68 | LIPF | 0.69865 | 3 | 0 | 3 |
| C1orf68 | MED24 | 0.69708 | 3 | 0 | 3 |
| C1orf68 | ERICH1 | 0.697064 | 3 | 0 | 3 |
| C1orf68 | ZNF358 | 0.696086 | 3 | 0 | 3 |
| C1orf68 | BTN1A1 | 0.694294 | 4 | 0 | 4 |
| C1orf68 | DCC | 0.693387 | 3 | 0 | 3 |
| C1orf68 | MUC6 | 0.69171 | 4 | 0 | 4 |
For details and further investigation, click here
