| Full name: olfactory receptor family 2 subfamily B member 2 | Alias Symbol: hs6M1-10|OR6-1|OR2B2Q | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 81697 | HGNC ID: HGNC:13966 | Ensembl Gene: ENSG00000168131 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR2B2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR2B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR2B2 | 81697 | 216408_at | -0.0419 | 0.8875 | |
| GSE20347 | OR2B2 | 81697 | 216408_at | -0.0056 | 0.9324 | |
| GSE23400 | OR2B2 | 81697 | 216408_at | -0.0602 | 0.0634 | |
| GSE26886 | OR2B2 | 81697 | 216408_at | -0.1953 | 0.0881 | |
| GSE29001 | OR2B2 | 81697 | 216408_at | -0.1294 | 0.6247 | |
| GSE38129 | OR2B2 | 81697 | 216408_at | -0.0853 | 0.0772 | |
| GSE45670 | OR2B2 | 81697 | 216408_at | 0.0077 | 0.9379 | |
| GSE53622 | OR2B2 | 81697 | 41449 | 0.1275 | 0.3538 | |
| GSE53624 | OR2B2 | 81697 | 41449 | 0.4295 | 0.0000 | |
| GSE63941 | OR2B2 | 81697 | 216408_at | 0.0779 | 0.5982 | |
| GSE77861 | OR2B2 | 81697 | 216408_at | -0.1315 | 0.2135 | |
| TCGA | OR2B2 | 81697 | RNAseq | 2.5862 | 0.0590 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR2B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR2B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR2B2 | 81697 | 4 | 2 | 24 | |
| GSE20123 | OR2B2 | 81697 | 4 | 2 | 24 | |
| GSE43470 | OR2B2 | 81697 | 5 | 0 | 38 | |
| GSE46452 | OR2B2 | 81697 | 1 | 10 | 48 | |
| GSE47630 | OR2B2 | 81697 | 7 | 4 | 29 | |
| GSE54993 | OR2B2 | 81697 | 2 | 1 | 67 | |
| GSE54994 | OR2B2 | 81697 | 11 | 4 | 38 | |
| GSE60625 | OR2B2 | 81697 | 0 | 1 | 10 | |
| GSE74703 | OR2B2 | 81697 | 5 | 0 | 31 | |
| GSE74704 | OR2B2 | 81697 | 0 | 1 | 19 | |
| TCGA | OR2B2 | 81697 | 15 | 21 | 60 |
Total number of gains: 54; Total number of losses: 46; Total Number of normals: 388.
Somatic mutations of OR2B2:
Generating mutation plots.
Highly correlated genes for OR2B2:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR2B2 | KCNJ10 | 0.700955 | 4 | 0 | 4 |
| OR2B2 | NOS1 | 0.683701 | 3 | 0 | 3 |
| OR2B2 | KIR2DS2 | 0.680315 | 4 | 0 | 4 |
| OR2B2 | S100G | 0.670563 | 5 | 0 | 4 |
| OR2B2 | BRS3 | 0.66928 | 4 | 0 | 4 |
| OR2B2 | NLRP14 | 0.667006 | 3 | 0 | 3 |
| OR2B2 | ADAM22 | 0.666405 | 5 | 0 | 5 |
| OR2B2 | ONECUT1 | 0.664974 | 5 | 0 | 4 |
| OR2B2 | DNMT3L | 0.663804 | 3 | 0 | 3 |
| OR2B2 | FCN2 | 0.662392 | 4 | 0 | 4 |
| OR2B2 | GML | 0.660312 | 4 | 0 | 3 |
| OR2B2 | TEX15 | 0.656896 | 5 | 0 | 5 |
| OR2B2 | KCNMB2 | 0.652793 | 3 | 0 | 3 |
| OR2B2 | RECK | 0.649413 | 3 | 0 | 3 |
| OR2B2 | KIR2DL5A | 0.648076 | 4 | 0 | 3 |
| OR2B2 | MYT1L | 0.64623 | 3 | 0 | 3 |
| OR2B2 | UMOD | 0.645509 | 4 | 0 | 4 |
| OR2B2 | GREB1L | 0.645008 | 3 | 0 | 3 |
| OR2B2 | HAL | 0.644645 | 5 | 0 | 5 |
| OR2B2 | FOLH1 | 0.644191 | 5 | 0 | 5 |
For details and further investigation, click here
