| Full name: THUMP domain containing 1 | Alias Symbol: FLJ20274|Tan1 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 55623 | HGNC ID: HGNC:23807 | Ensembl Gene: ENSG00000066654 | OMIM ID: 616662 |
| Drug and gene relationship at DGIdb | |||
Expression of THUMPD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THUMPD1 | 55623 | 206555_s_at | -0.4241 | 0.4909 | |
| GSE20347 | THUMPD1 | 55623 | 206555_s_at | -0.1342 | 0.2720 | |
| GSE23400 | THUMPD1 | 55623 | 206555_s_at | 0.0981 | 0.2656 | |
| GSE26886 | THUMPD1 | 55623 | 206555_s_at | -0.3859 | 0.2239 | |
| GSE29001 | THUMPD1 | 55623 | 206555_s_at | 0.0282 | 0.9458 | |
| GSE38129 | THUMPD1 | 55623 | 206555_s_at | -0.2301 | 0.0310 | |
| GSE45670 | THUMPD1 | 55623 | 206555_s_at | -0.2553 | 0.0461 | |
| GSE53622 | THUMPD1 | 55623 | 5572 | -0.1871 | 0.0155 | |
| GSE53624 | THUMPD1 | 55623 | 5572 | -0.1494 | 0.0959 | |
| GSE63941 | THUMPD1 | 55623 | 206555_s_at | -0.2745 | 0.5635 | |
| GSE77861 | THUMPD1 | 55623 | 206555_s_at | -0.0633 | 0.8639 | |
| GSE97050 | THUMPD1 | 55623 | A_24_P90878 | -0.6071 | 0.0734 | |
| SRP007169 | THUMPD1 | 55623 | RNAseq | 0.9883 | 0.0144 | |
| SRP008496 | THUMPD1 | 55623 | RNAseq | 1.3807 | 0.0000 | |
| SRP064894 | THUMPD1 | 55623 | RNAseq | -0.2820 | 0.0352 | |
| SRP133303 | THUMPD1 | 55623 | RNAseq | 0.1635 | 0.2560 | |
| SRP159526 | THUMPD1 | 55623 | RNAseq | -0.3013 | 0.0514 | |
| SRP193095 | THUMPD1 | 55623 | RNAseq | -0.2842 | 0.0007 | |
| SRP219564 | THUMPD1 | 55623 | RNAseq | -0.4819 | 0.0448 | |
| TCGA | THUMPD1 | 55623 | RNAseq | -0.2025 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by THUMPD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THUMPD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THUMPD1 | 55623 | 6 | 3 | 21 | |
| GSE20123 | THUMPD1 | 55623 | 6 | 2 | 22 | |
| GSE43470 | THUMPD1 | 55623 | 3 | 3 | 37 | |
| GSE46452 | THUMPD1 | 55623 | 38 | 1 | 20 | |
| GSE47630 | THUMPD1 | 55623 | 11 | 6 | 23 | |
| GSE54993 | THUMPD1 | 55623 | 3 | 5 | 62 | |
| GSE54994 | THUMPD1 | 55623 | 3 | 10 | 40 | |
| GSE60625 | THUMPD1 | 55623 | 4 | 0 | 7 | |
| GSE74703 | THUMPD1 | 55623 | 3 | 2 | 31 | |
| GSE74704 | THUMPD1 | 55623 | 3 | 1 | 16 | |
| TCGA | THUMPD1 | 55623 | 19 | 13 | 64 |
Total number of gains: 99; Total number of losses: 46; Total Number of normals: 343.
Somatic mutations of THUMPD1:
Generating mutation plots.
Highly correlated genes for THUMPD1:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THUMPD1 | IFT74 | 0.80071 | 4 | 0 | 3 |
| THUMPD1 | GUF1 | 0.796735 | 3 | 0 | 3 |
| THUMPD1 | ZFP62 | 0.767129 | 3 | 0 | 3 |
| THUMPD1 | SRFBP1 | 0.766088 | 3 | 0 | 3 |
| THUMPD1 | RSL24D1 | 0.758845 | 4 | 0 | 4 |
| THUMPD1 | N4BP2L1 | 0.73933 | 4 | 0 | 4 |
| THUMPD1 | ATP9A | 0.737652 | 3 | 0 | 3 |
| THUMPD1 | PHF11 | 0.732907 | 3 | 0 | 3 |
| THUMPD1 | C21orf91 | 0.729223 | 4 | 0 | 4 |
| THUMPD1 | RPRD1A | 0.721821 | 3 | 0 | 3 |
| THUMPD1 | EED | 0.721543 | 3 | 0 | 3 |
| THUMPD1 | CTCF | 0.721238 | 4 | 0 | 4 |
| THUMPD1 | SCYL3 | 0.718449 | 3 | 0 | 3 |
| THUMPD1 | PDZD11 | 0.716271 | 3 | 0 | 3 |
| THUMPD1 | MRPL48 | 0.715729 | 3 | 0 | 3 |
| THUMPD1 | MNS1 | 0.712286 | 3 | 0 | 3 |
| THUMPD1 | UHRF2 | 0.709825 | 3 | 0 | 3 |
| THUMPD1 | LIPT1 | 0.706516 | 4 | 0 | 3 |
| THUMPD1 | UTP3 | 0.705876 | 4 | 0 | 4 |
| THUMPD1 | ZNF565 | 0.704935 | 4 | 0 | 3 |
For details and further investigation, click here
